An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells

por Cao, Kaixiang, Collings, Clayton K., Morgan, Marc A., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Smith, Edwin R., Shilatifard, Ali
Publicado 2018

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

por Cao, Kaixiang, Collings, Clayton K., Marshall, Stacy A., Morgan, Marc A., Rendleman, Emily J., Wang, Lu, Sze, Christie C., Sun, Tianjiao, Bartom, Elizabeth T., Shilatifard, Ali
Publicado 2017

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation

por Sze, Christie C., Cao, Kaixiang, Collings, Clayton K., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Chen, Fei Xavier, Morgan, Marc A., Wang, Lu, Shilatifard, Ali
Publicado 2017

A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism

por Wang, Lu, Collings, Clayton K., Zhao, Zibo, Cozzolino, Kira Alia, Ma, Quanhong, Liang, Kaiwei, Marshall, Stacy A., Sze, Christie C., Hashizume, Rintaro, Savas, Jeffrey Nicholas, Shilatifard, Ali
Publicado 2017

Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family

por Sze, Christie C., Ozark, Patrick A., Cao, Kaixiang, Ugarenko, Michal, Das, Siddhartha, Wang, Lu, Marshall, Stacy A., Rendleman, Emily J., Ryan, Caila A., Zha, Didi, Douillet, Delphine, Chen, Fei Xavier, Shilatifard, Ali
Publicado 2020

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia

por Zhao, Zibo, Wang, Lu, Volk, Andrew G., Birch, Noah W., Stoltz, Kristen L., Bartom, Elizabeth T., Marshall, Stacy A., Rendleman, Emily J., Nestler, Carson M., Shilati, Joseph, Schiltz, Gary E., Crispino, John D., Shilatifard, Ali
Publicado 2019

TET2 coactivates gene expression through demethylation of enhancers

por Wang, Lu, Ozark, Patrick A., Smith, Edwin R., Zhao, Zibo, Marshall, Stacy A., Rendleman, Emily J., Piunti, Andrea, Ryan, Caila, Whelan, Anna L., Helmin, Kathryn A., Morgan, Marc Alard, Zou, Lihua, Singer, Benjamin D., Shilatifard, Ali
Publicado 2018

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

por Morgan, Marc A.J., Rickels, Ryan A., Collings, Clayton K., He, Xiaolin, Cao, Kaixiang, Herz, Hans-Martin, Cozzolino, Kira A., Abshiru, Nebiyu A., Marshall, Stacy A., Rendleman, Emily J., Sze, Christie C., Piunti, Andrea, Kelleher, Neil L., Savas, Jeffrey N., Shilatifard, Ali
Publicado 2017

TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas

por Gonzalez-Buendia, Edgar, Zhao, Junfei, Wang, Lu, Mukherjee, Subhas, Zhang, Daniel, Arrieta, Víctor A., Feldstein, Eric, Kane, J. Robert, Kang, Seong Jae, Lee-Chang, Catalina, Mahajan, Aayushi, Chen, Li, Realubit, Ronald, Karan, Charles, Magnuson, Lisa, Horbinski, Craig, Marshall, Stacy A., Sarkaria, Jann N., Mohyeldin, Ahmed, Nakano, Ichiro, Bansal, Mukesh, James, Charles D., Brat, Daniel J., Ahmed, Atique, Canoll, Peter, Rabadan, Raul, Shilatifard, Ali, Sonabend, Adam M.
Publicado 2021

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

por Misharin, Alexander V., Morales-Nebreda, Luisa, Reyfman, Paul A., Cuda, Carla M., Walter, James M., McQuattie-Pimentel, Alexandra C., Chen, Ching-I, Anekalla, Kishore R., Joshi, Nikita, Williams, Kinola J.N., Abdala-Valencia, Hiam, Yacoub, Tyrone J., Chi, Monica, Chiu, Stephen, Gonzalez-Gonzalez, Francisco J., Gates, Khalilah, Lam, Anna P., Nicholson, Trevor T., Homan, Philip J., Soberanes, Saul, Dominguez, Salina, Morgan, Vince K., Saber, Rana, Shaffer, Alexander, Hinchcliff, Monique, Marshall, Stacy A., Bharat, Ankit, Berdnikovs, Sergejs, Bhorade, Sangeeta M., Bartom, Elizabeth T., Morimoto, Richard I., Balch, William E., Sznajder, Jacob I., Chandel, Navdeep S., Mutlu, Gökhan M., Jain, Manu, Gottardi, Cara J., Singer, Benjamin D., Ridge, Karen M., Bagheri, Neda, Shilatifard, Ali, Budinger, G.R. Scott, Perlman, Harris
Publicado 2017

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

por Reyfman, Paul A., Walter, James M., Joshi, Nikita, Anekalla, Kishore R., McQuattie-Pimentel, Alexandra C., Chiu, Stephen, Fernandez, Ramiro, Akbarpour, Mahzad, Chen, Ching-I, Ren, Ziyou, Verma, Rohan, Abdala-Valencia, Hiam, Nam, Kiwon, Chi, Monica, Han, SeungHye, Gonzalez-Gonzalez, Francisco J., Soberanes, Saul, Watanabe, Satoshi, Williams, Kinola J. N., Flozak, Annette S., Nicholson, Trevor T., Morgan, Vince K., Winter, Deborah R., Hinchcliff, Monique, Hrusch, Cara L., Guzy, Robert D., Bonham, Catherine A., Sperling, Anne I., Bag, Remzi, Hamanaka, Robert B., Mutlu, Gökhan M., Yeldandi, Anjana V., Marshall, Stacy A., Shilatifard, Ali, Amaral, Luis A. N., Perlman, Harris, Sznajder, Jacob I., Argento, A. Christine, Gillespie, Colin T., Dematte, Jane, Jain, Manu, Singer, Benjamin D., Ridge, Karen M., Lam, Anna P., Bharat, Ankit, Bhorade, Sangeeta M., Gottardi, Cara J., Budinger, G. R. Scott, Misharin, Alexander V.
Publicado 2019