Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza

por Günther, Sira C., Martínez-Romero, Carles, Sempere Borau, Milagros, Pham, Christine T. N., García-Sastre, Adolfo, Stertz, Silke
Publicado 2022

Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection

por Muñoz-Moreno, Raquel, Cuesta-Geijo, Miguel Ángel, Martínez-Romero, Carles, Barrado-Gil, Lucía, Galindo, Inmaculada, García-Sastre, Adolfo, Alonso, Covadonga
Publicado 2016

Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains

por Sironi, Francesca, Malnati, Mauro, Mongelli, Nicola, Cozzi, Paolo, Guzzo, Christina, Ghezzi, Silvia, Martínez-Romero, Carles, García-Sastre, Adolfo, Lusso, Paolo, Jabes, Daniela, Biswas, Priscilla
Publicado 2015

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

por Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo
Publicado 2014

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells

por Bosch, Almudena, Panoutsopoulou, Konstantina, Corominas, Josep Maria, Gimeno, Ramón, Moreno-Bueno, Gema, Martín-Caballero, Juan, Morales, Saleta, Lobato, Tania, Martínez-Romero, Carles, Farias, Eduardo F., Mayol, Xavier, Cano, Amparo, Hernández-Muáoz, Inmaculada
Publicado 2014

IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization

por Lanz, Caroline, Schotsaert, Michael, Magnus, Carsten, Karakus, Umut, Hunziker, Annika, Sempere Borau, Milagros, Martínez-Romero, Carles, Spieler, Eva E., Günther, Sira C., Moritz, Eva, Hale, Benjamin G., Trkola, Alexandra, García-Sastre, Adolfo, Stertz, Silke
Publicado 2021

Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics

por Dai, Meiling, Du, Wenjuan, Martínez-Romero, Carles, Leenders, Tim, Wennekes, Tom, Rimmelzwaan, Guus F., van Kuppeveld, Frank J. M., Fouchier, Ron A. M., Garcia-Sastre, Adolfo, de Vries, Erik, de Haan, Cornelis A. M.
Publicado 2021

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death

por Hartmann, Boris M., Albrecht, Randy A., Zaslavsky, Elena, Nudelman, German, Pincas, Hanna, Marjanovic, Nada, Schotsaert, Michael, Martínez-Romero, Carles, Fenutria, Rafael, Ingram, Justin P., Ramos, Irene, Fernandez-Sesma, Ana, Balachandran, Siddharth, García-Sastre, Adolfo, Sealfon, Stuart C.
Publicado 2017

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

por Muñoz-Moreno, Raquel, Martínez-Romero, Carles, Blanco-Melo, Daniel, Forst, Christian V., Nachbagauer, Raffael, Benitez, Asiel Arturo, Mena, Ignacio, Aslam, Sadaf, Balasubramaniam, Vinod, Lee, Ilseob, Panis, Maryline, Ayllón, Juan, Sachs, David, Park, Man-Seong, Krammer, Florian, tenOever, Benjamin R., García-Sastre, Adolfo
Publicado 2019

N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses

por Broszeit, Frederik, Tzarum, Netanel, Zhu, Xueyong, Nemanichvili, Nikoloz, Eggink, Dirk, Leenders, Tim, Li, Zeshi, Liu, Lin, Wolfert, Margreet A., Papanikolaou, Andreas, Martínez-Romero, Carles, Gagarinov, Ivan A., Yu, Wenli, García-Sastre, Adolfo, Wennekes, Tom, Okamatsu, Masatoshi, Verheije, Monique H., Wilson, Ian A., Boons, Geert-Jan, de Vries, Robert P.
Publicado 2019

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

por Ramos, Irene, Smith, Gregory, Ruf-Zamojski, Frederique, Martínez-Romero, Carles, Fribourg, Miguel, Carbajal, Edwin A., Hartmann, Boris M., Nair, Venugopalan D., Marjanovic, Nada, Monteagudo, Paula L., DeJesus, Veronica A., Mutetwa, Tinaye, Zamojski, Michel, Tan, Gene S., Jayaprakash, Ciriyam, Zaslavsky, Elena, Albrecht, Randy A., Sealfon, Stuart C., García-Sastre, Adolfo, Fernandez-Sesma, Ana
Publicado 2019

The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

por Rathnasinghe, Raveen, Jangra, Sonia, Cupic, Anastasija, Martínez-Romero, Carles, Mulder, Lubbertus C.F., Kehrer, Thomas, Yildiz, Soner, Choi, Angela, Mena, Ignacio, De Vrieze, Jana, Aslam, Sadaf, Stadlbauer, Daniel, Meekins, David A., McDowell, Chester D., Balaraman, Velmurugan, Richt, Juergen A., De Geest, Bruno G., Miorin, Lisa, Krammer, Florian, Simon, Viviana, García-Sastre, Adolfo, Schotsaert, Michael
Publicado 2021

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

por White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
Publicado 2021

Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera

por Rathnasinghe, Raveen, Jangra, Sonia, Ye, Chengjin, Cupic, Anastasija, Singh, Gagandeep, Martínez-Romero, Carles, Mulder, Lubbertus C. F., Kehrer, Thomas, Yildiz, Soner, Choi, Angela, Yeung, Stephen T., Mena, Ignacio, Gillespie, Virginia, De Vrieze, Jana, Aslam, Sadaf, Stadlbauer, Daniel, Meekins, David A., McDowell, Chester D., Balaraman, Velmurugan, Corley, Michael J., Richt, Juergen A., De Geest, Bruno G., Miorin, Lisa, Krammer, Florian, Martinez-Sobrido, Luis, Simon, Viviana, García-Sastre, Adolfo, Schotsaert, Michael
Publicado 2022

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry

por Yang, Shu, Xu, Miao, Lee, Emily M, Gorshkov, Kirill, Shiryaev, Sergey A., He, Shihua, Sun, Wei, Cheng, Yu-Shan, Hu, Xin, Tharappel, Anil Mathew, Lu, Billy, Pinto, Antonella, Farhy, Chen, Huang, Chun-Teng, Zhang, Zirui, Zhu, Wenjun, Wu, Yuying, Zhou, Yi, Song, Guang, Zhu, Heng, Shamim, Khalida, Martínez-Romero, Carles, García-Sastre, Adolfo, Preston, Richard A., Jayaweera, Dushyantha T., Huang, Ruili, Huang, Wenwei, Xia, Menghang, Simeonov, Anton, Ming, Guoli, Qiu, Xiangguo, Terskikh, Alexey V., Tang, Hengli, Song, Hongjun, Zheng, Wei
Publicado 2018

Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models

por Choudhary, Shambhunath, Kanevsky, Isis, Yildiz, Soner, Sellers, Rani S., Swanson, Kena A., Franks, Tania, Rathnasinghe, Raveen, Munoz-Moreno, Raquel, Jangra, Sonia, Gonzalez, Olga, Meade, Philip, Coskran, Timothy, Qian, Jessie, Lanz, Thomas A., Johnson, Jillian G., Tierney, Cassandra A, Smith, Justin D., Tompkins, Kristin, Illenberger, Arthur, Corts, Paula, Ciolino, Tara, Dormitzer, Philip R., Dick, Edward J., Shivanna, Vinay, Hall-Ursone, Shannan, Cole, Journey, Kaushal, Deepak, Fontenot, Jane A., Martinez-Romero, Carles, McMahon, Meagan, Krammer, Florian, Schotsaert, Michael, García-Sastre, Adolfo
Publicado 2022

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

por Ho, Jessica Sook Yuin, Angel, Matthew, Ma, Yixuan, Sloan, Elizabeth, Wang, Guojun, Martinez-Romero, Carles, Alenquer, Marta, Roudko, Vladimir, Chung, Liliane, Zheng, Simin, Chang, Max, Fstkchyan, Yesai, Clohisey, Sara, Dinan, Adam M., Gibbs, James, Gifford, Robert, Shen, Rong, Gu, Quan, Irigoyen, Nerea, Campisi, Laura, Huang, Cheng, Zhao, Nan, Jones, Joshua D., van Knippenberg, Ingeborg, Zhu, Zeyu, Moshkina, Natasha, Meyer, Léa, Noel, Justine, Peralta, Zuleyma, Rezelj, Veronica, Kaake, Robyn, Rosenberg, Brad, Wang, Bo, Wei, Jiajie, Paessler, Slobodan, Wise, Helen M., Johnson, Jeffrey, Vannini, Alessandro, Amorim, Maria João, Baillie, J. Kenneth, Miraldi, Emily R., Benner, Christopher, Brierley, Ian, Digard, Paul, Łuksza, Marta, Firth, Andrew E., Krogan, Nevan, Greenbaum, Benjamin D., MacLeod, Megan K., van Bakel, Harm, Garcìa-Sastre, Adolfo, Yewdell, Jonathan W., Hutchinson, Edward, Marazzi, Ivan
Publicado 2020