Towards a Molecular Understanding of the Link between Imatinib Resistance and Kinase Conformational Dynamics

por Lovera, Silvia, Morando, Maria, Pucheta-Martinez, Encarna, Martinez-Torrecuadrada, Jorge L., Saladino, Giorgio, Gervasio, Francesco L.
Publicado 2015

Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome

por Pucheta-Martinez, Encarna, D’Amelio, Nicola, Lelli, Moreno, Martinez-Torrecuadrada, Jorge L., Sudol, Marius, Saladino, Giorgio, Gervasio, Francesco Luigi
Publicado 2016

An Allosteric Cross-Talk Between the Activation Loop and the ATP Binding Site Regulates the Activation of Src Kinase

por Pucheta-Martínez, Encarna, Saladino, Giorgio, Morando, Maria Agnese, Martinez-Torrecuadrada, Jorge, Lelli, Moreno, Sutto, Ludovico, D’Amelio, Nicola, Gervasio, Francesco Luigi
Publicado 2016

Multiple cancer pathways regulate telomere protection

por Bejarano, Leire, Bosso, Giuseppe, Louzame, Jessica, Serrano, Rosa, Gómez‐Casero, Elena, Martínez‐Torrecuadrada, Jorge, Martínez, Sonia, Blanco‐Aparicio, Carmen, Pastor, Joaquín, Blasco, Maria A
Publicado 2019

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity

por Frye, Maike, Stritt, Simon, Ortsäter, Henrik, Hernandez Vasquez, Magda, Kaakinen, Mika, Vicente, Andres, Wiseman, John, Eklund, Lauri, Martínez-Torrecuadrada, Jorge L, Vestweber, Dietmar, Mäkinen, Taija
Publicado 2020

Modulation of telomere protection by the PI3K/AKT pathway

por Méndez-Pertuz, Marinela, Martínez, Paula, Blanco-Aparicio, Carmen, Gómez-Casero, Elena, Belen García, Ana, Martínez-Torrecuadrada, Jorge, Palafox, Marta, Cortés, Javier, Serra, Violeta, Pastor, Joaquin, Blasco, Maria A.
Publicado 2017

MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management

por Morcillo, Miguel Ángel, García de Lucas, Ángel, Oteo, Marta, Romero, Eduardo, Magro, Natalia, Ibáñez, Marta, Martínez, Alfonso, Garaulet, Guillermo, Arroyo, Alicia G., López-Casas, Pedro Pablo, Hidalgo, Manuel, Mulero, Francisca, Martínez-Torrecuadrada, Jorge
Publicado 2018

CSF1R Protein Expression in Reactive Lymphoid Tissues and Lymphoma: Its Relevance in Classical Hodgkin Lymphoma

por Martín-Moreno, Ana M., Roncador, Giovanna, Maestre, Lorena, Mata, Elena, Jiménez, Scherezade, Martínez-Torrecuadrada, Jorge L., Reyes-García, Ana I., Rubio, Carmen, Tomás, José F., Estévez, Mónica, Pulford, Karen, Piris, Miguel A., García, Juan F.
Publicado 2015

Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR

por Compte, Marta, Harwood, Seandean L., Martínez-Torrecuadrada, Jorge, Perez-Chacon, Gema, González-García, Patricia, Tapia-Galisteo, Antonio, Van Bergen en Henegouwen, Paul M. P., Sánchez, Aránzazu, Fabregat, Isabel, Sanz, Laura, Zapata, Juan M., Alvarez-Vallina, Luis
Publicado 2021

Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging

por Mulero, Francisca, Oteo, Marta, Garaulet, Guillermo, Magro, Natalia, Rebollo, Lluvia, Medrano, Guillermo, Santiveri, Clara, Romero, Eduardo, Sellek, Ricela E., Margolles, Yago, Campos-Olivas, Ramón, Arroyo, Alicia G., Fernández, Luis Angel, Morcillo, Miguel Angel, Martínez-Torrecuadrada, Jorge L.
Publicado 2022

EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells

por Krusche, Benjamin, Ottone, Cristina, Clements, Melanie P, Johnstone, Ewan R, Goetsch, Katrin, Lieven, Huang, Mota, Silvia G, Singh, Poonam, Khadayate, Sanjay, Ashraf, Azhaar, Davies, Timothy, Pollard, Steven M, De Paola, Vincenzo, Roncaroli, Federico, Martinez-Torrecuadrada, Jorge, Bertone, Paul, Parrinello, Simona
Publicado 2016

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

por Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Publicado 2018