Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT

por Tièche, Colin Charles, Peng, Ren-Wang, Dorn, Patrick, Froment, Laurène, Schmid, Ralph Alexander, Marti, Thomas Michael
Publicado 2016

Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells

por Dorn, Patrick, Tièche, Colin Charles, Peng, Ren-Wang, Froment, Laurène, Schmid, Ralph Alexander, Marti, Thomas Michael
Publicado 2016

Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma

por Karatkevich, Darya, Deng, Haibin, Gao, Yanyun, Flint, Emilio, Peng, Ren-Wang, Schmid, Ralph Alexander, Dorn, Patrick, Marti, Thomas Michael
Publicado 2022

Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR)

por Gao, Yanyun, Zens, Philipp, Su, Min, Gemperli, Camila Anna, Yang, Haitang, Deng, Haibin, Yang, Zhang, Xu, Duo, Hall, Sean R. R., Berezowska, Sabina, Dorn, Patrick, Peng, Ren-Wang, Schmid, Ralph Alexander, Wang, Wenxiang, Marti, Thomas Michael
Publicado 2021

A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System

por Sengupta, Arunima, Roldan, Nuria, Kiener, Mirjam, Froment, Laurène, Raggi, Giulia, Imler, Theo, de Maddalena, Lea, Rapet, Aude, May, Tobias, Carius, Patrick, Schneider-Daum, Nicole, Lehr, Claus-Michael, Kruithof-de Julio, Marianna, Geiser, Thomas, Marti, Thomas Michael, Stucki, Janick D., Hobi, Nina, Guenat, Olivier T.
Publicado 2022

Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549()

por Tièche, Colin Charles, Gao, Yanyun, Bührer, Elias Daniel, Hobi, Nina, Berezowska, Sabina Anna, Wyler, Kurt, Froment, Laurène, Weis, Stefan, Peng, Ren-Wang, Bruggmann, Rémy, Schär, Primo, Amrein, Michael Alex, Hall, Sean Ralph Robert, Dorn, Patrick, Kocher, Gregor, Riether, Carsten, Ochsenbein, Adrian, Schmid, Ralph Alexander, Marti, Thomas Michael
Publicado 2018

Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damag...

por Deng, Haibin, Gao, Yanyun, Trappetti, Verdiana, Hertig, Damian, Karatkevich, Darya, Losmanova, Tereza, Urzi, Christian, Ge, Huixiang, Geest, Gerrit Adriaan, Bruggmann, Remy, Djonov, Valentin, Nuoffer, Jean-Marc, Vermathen, Peter, Zamboni, Nicola, Riether, Carsten, Ochsenbein, Adrian, Peng, Ren-Wang, Kocher, Gregor Jan, Schmid, Ralph Alexander, Dorn, Patrick, Marti, Thomas Michael
Publicado 2022