Diversity in Genomic Studies: A Roadmap to Address the Imbalance

por Fatumo, Segun, Chikowore, Tinashe, Choudhury, Ananyo, Ayub, Muhammad, Martin, Alicia R., Kuchenbäcker, Karoline
Publicado 2022

STORMSeq: An Open-Source, User-Friendly Pipeline for Processing Personal Genomics Data in the Cloud

por Karczewski, Konrad J., Fernald, Guy Haskin, Martin, Alicia R., Snyder, Michael, Tatonetti, Nicholas P., Dudley, Joel T.
Publicado 2014

Leveraging fine-mapping and multi-population training data to improve cross-population polygenic risk scores

por Weissbrod, Omer, Kanai, Masahiro, Shi, Huwenbo, Gazal, Steven, Peyrot, Wouter J., Khera, Amit V., Okada, Yukinori, Martin, Alicia R., Finucane, Hilary, Price, Alkes L.
Publicado 2022

Prediction and stratification of longitudinal risk for chronic obstructive pulmonary disease across smoking behaviors

por He, Yixuan, Qian, David C., Diao, James A., Cho, Michael H., Silverman, Edwin K., Gusev, Alexander, Manrai, Arjun K., Martin, Alicia R., Patel, Chirag J.
Publicado 2023

Fine-Scale Genetic Structure in Finland

por Kerminen, Sini, Havulinna, Aki S., Hellenthal, Garrett, Martin, Alicia R., Sarin, Antti-Pekka, Perola, Markus, Palotie, Aarno, Salomaa, Veikko, Daly, Mark J., Ripatti, Samuli, Pirinen, Matti
Publicado 2017

Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

por Wang, Ying, Kanai, Masahiro, Tan, Taotao, Kamariza, Mireille, Tsuo, Kristin, Yuan, Kai, Zhou, Wei, Okada, Yukinori, Huang, Hailiang, Turley, Patrick, Atkinson, Elizabeth G., Martin, Alicia R.
Publicado 2023

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases

por Truong, Buu, Hull, Leland E., Ruan, Yunfeng, Huang, Qin Qin, Hornsby, Whitney, Martin, Hilary, van Heel, David A., Wang, Ying, Martin, Alicia R., Lee, S. Hong, Natarajan, Pradeep
Publicado 2023

Low and differential polygenic score generalizability among African populations due largely to genetic diversity

por Majara, Lerato, Kalungi, Allan, Koen, Nastassja, Tsuo, Kristin, Wang, Ying, Gupta, Rahul, Nkambule, Lethukuthula L., Zar, Heather, Stein, Dan J., Kinyanda, Eugene, Atkinson, Elizabeth G., Martin, Alicia R.
Publicado 2023

Improving Polygenic Prediction in Ancestrally Diverse Populations

por Ruan, Yunfeng, Lin, Yen-Feng, Feng, Yen-Chen Anne, Chen, Chia-Yen, Lam, Max, Guo, Zhenglin, He, Lin, Sawa, Akira, Martin, Alicia R., Qin, Shengying, Huang, Hailiang, Ge, Tian
Publicado 2022

Transcriptome Sequencing from Diverse Human Populations Reveals Differentiated Regulatory Architecture

por Martin, Alicia R., Costa, Helio A., Lappalainen, Tuuli, Henn, Brenna M., Kidd, Jeffrey M., Yee, Muh-Ching, Grubert, Fabian, Cann, Howard M., Snyder, Michael, Montgomery, Stephen B., Bustamante, Carlos D.
Publicado 2014

Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity

por Tsuo, Kristin, Zhou, Wei, Wang, Ying, Kanai, Masahiro, Namba, Shinichi, Gupta, Rahul, Majara, Lerato, Nkambule, Lethukuthula L., Morisaki, Takayuki, Okada, Yukinori, Neale, Benjamin M., Daly, Mark J., Martin, Alicia R.
Publicado 2022

Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies

por Wojcik, Genevieve L., Fuchsberger, Christian, Taliun, Daniel, Welch, Ryan, Martin, Alicia R, Shringarpure, Suyash, Carlson, Christopher S., Abecasis, Goncalo, Kang, Hyun Min, Boehnke, Michael, Bustamante, Carlos D., Gignoux, Christopher R., Kenny, Eimear E.
Publicado 2018

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

por Sohail, Mashaal, Maier, Robert M, Ganna, Andrea, Bloemendal, Alex, Martin, Alicia R, Turchin, Michael C, Chiang, Charleston WK, Hirschhorn, Joel, Daly, Mark J, Patterson, Nick, Neale, Benjamin, Mathieson, Iain, Reich, David, Sunyaev, Shamil R
Publicado 2019

Tractor uses local ancestry to enable inclusion of admixed individuals into GWAS and boost power

por Atkinson, Elizabeth G., Maihofer, Adam X., Kanai, Masahiro, Martin, Alicia R., Karczewski, Konrad J., Santoro, Marcos L., Ulirsch, Jacob C., Kamatani, Yoichiro, Okada, Yukinori, Finucane, Hilary K., Koenen, Karestan C., Nievergelt, Caroline M., Daly, Mark J., Neale, Benjamin M.
Publicado 2021

Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis): a case-control study protocol and GWAS in Ethiopia, Kenya, South Africa and Uganda

por Stevenson, Anne, Akena, Dickens, Stroud, Rocky E, Atwoli, Lukoye, Campbell, Megan M, Chibnik, Lori B, Kwobah, Edith, Kariuki, Symon M, Martin, Alicia R, de Menil, Victoria, Newton, Charles R J C, Sibeko, Goodman, Stein, Dan J, Teferra, Solomon, Zingela, Zukiswa, Koenen, Karestan C
Publicado 2019

Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes

por Ávila-Arcos, María C, McManus, Kimberly F, Sandoval, Karla, Rodríguez-Rodríguez, Juan Esteban, Villa-Islas, Viridiana, Martin, Alicia R, Luisi, Pierre, Peñaloza-Espinosa, Rosenda I, Eng, Celeste, Huntsman, Scott, Burchard, Esteban G, Gignoux, Christopher R, Bustamante, Carlos D, Moreno-Estrada, Andrés
Publicado 2020

Decoding Genetics, Ancestry, and Geospatial Context for Precision Health

por Koyama, Satoshi, Wang, Ying, Paruchuri, Kaavya, Uddin, Md Mesbah, Cho, So Mi J., Urbut, Sarah M., Haidermota, Sara, Hornsby, Whitney E., Green, Robert C., Daly, Mark J., Neale, Benjamin M., Ellinor, Patrick T., Smoller, Jordan W., Lebo, Matthew S., Karlson, Elizabeth W., Martin, Alicia R., Natarajan, Pradeep
Publicado 2023

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

por Gay, Nicole R., Gloudemans, Michael, Antonio, Margaret L., Abell, Nathan S., Balliu, Brunilda, Park, YoSon, Martin, Alicia R., Musharoff, Shaila, Rao, Abhiram S., Aguet, François, Barbeira, Alvaro N., Bonazzola, Rodrigo, Hormozdiari, Farhad, Ardlie, Kristin G., Brown, Christopher D., Im, Hae Kyung, Lappalainen, Tuuli, Wen, Xiaoquan, Montgomery, Stephen B.
Publicado 2020

Genome-wide risk prediction of common diseases across ancestries in one million people

por Mars, Nina, Kerminen, Sini, Feng, Yen-Chen A., Kanai, Masahiro, Läll, Kristi, Thomas, Laurent F., Skogholt, Anne Heidi, della Briotta Parolo, Pietro, Neale, Benjamin M., Smoller, Jordan W., Gabrielsen, Maiken E., Hveem, Kristian, Mägi, Reedik, Matsuda, Koichi, Okada, Yukinori, Pirinen, Matti, Palotie, Aarno, Ganna, Andrea, Martin, Alicia R., Ripatti, Samuli
Publicado 2022

A harmonized public resource of deeply sequenced diverse human genomes

por Koenig, Zan, Yohannes, Mary T., Nkambule, Lethukuthula L., Goodrich, Julia K., Kim, Heesu Ally, Zhao, Xuefang, Wilson, Michael W., Tiao, Grace, Hao, Stephanie P., Sahakian, Nareh, Chao, Katherine R., Rehm, Heidi L., Neale, Benjamin M., Talkowski, Michael E., Daly, Mark J., Brand, Harrison, Karczewski, Konrad J., Atkinson, Elizabeth G., Martin, Alicia R.
Publicado 2023