Computational Analysis of an Autophagy/Translation Switch Based on Mutual Inhibition of MTORC1 and ULK1

por Szymańska, Paulina, Martin, Katie R., MacKeigan, Jeffrey P., Hlavacek, William S., Lipniacki, Tomasz
Publicado 2015

Mitochondrial Morphological Features Are Associated with Fission and Fusion Events

por Westrate, Laura M., Drocco, Jeffrey A., Martin, Katie R., Hlavacek, William S., MacKeigan, Jeffrey P.
Publicado 2014

PI3K-C2α knockdown decreases autophagy and maturation of endocytic vesicles

por Merrill, Nathan M., Schipper, Joshua L., Karnes, Jonathan B., Kauffman, Audra L., Martin, Katie R., MacKeigan, Jeffrey P.
Publicado 2017

Computational model for autophagic vesicle dynamics in single cells

por Martin, Katie R., Barua, Dipak, Kauffman, Audra L., Westrate, Laura M., Posner, Richard G., Hlavacek, William S., MacKeigan, Jeffrey P.
Publicado 2013

Identification of Small Molecule Inhibitors of PTPσ through an Integrative Virtual and Biochemical Approach

por Martin, Katie R., Narang, Pooja, Xu, Yong, Kauffman, Audra L., Petit, Joachim, Xu, H. Eric, Meurice, Nathalie, MacKeigan, Jeffrey P.
Publicado 2012

The Pseudophosphatase MK-STYX Physically and Genetically Interacts with the Mitochondrial Phosphatase PTPMT1

por Niemi, Natalie M., Sacoman, Juliana L., Westrate, Laura M., Gaither, L. Alex, Lanning, Nathan J., Martin, Katie R., MacKeigan, Jeffrey P.
Publicado 2014

Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib

por Goodall, Megan L, Wang, Tong, Martin, Katie R, Kortus, Matthew G, Kauffman, Audra L, Trent, Jeffrey M, Gately, Stephen, MacKeigan, Jeffrey P
Publicado 2014

A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress

por Martin, Katie R., Celano, Stephanie L., Solitro, Abigail R., Gunaydin, Hakan, Scott, Mark, O'Hagan, Ronan C., Shumway, Stuart D., Fuller, Peter, MacKeigan, Jeffrey P.
Publicado 2018

Spectrum of germline and somatic mitochondrial DNA variants in Tuberous Sclerosis Complex

por Giannikou, Krinio, Martin, Katie R., Abdel-Azim, Ahmad G., Pamir, Kaila J., Hougard, Thomas R., Bagwe, Shefali, Tang, Yan, MacKeigan, Jeffrey P., Kwiatkowski, David J., Henske, Elizabeth P., Lam, Hilaire C.
Publicado 2023

Identification of Kinases Responsible for p53-Dependent Autophagy

por Celano, Stephanie L., Yco, Lisette P., Kortus, Matthew G., Solitro, Abigail R., Gunaydin, Hakan, Scott, Mark, Spooner, Edward, O'Hagan, Ronan C., Fuller, Peter, Martin, Katie R., Shumway, Stuart D., MacKeigan, Jeffrey P.
Publicado 2019

Chemical Biology Screening Identifies a Vulnerability to Checkpoint Kinase Inhibitors in TSC2-Deficient Renal Angiomyolipomas

por Vaughan, Robert M., Kordich, Jennifer J., Chan, Chun-Yuan, Sasi, Nanda K., Celano, Stephanie L., Sisson, Kellie A., Van Baren, Megan, Kortus, Matthew G., Aguiar, Dean J., Martin, Katie R., MacKeigan, Jeffrey P.
Publicado 2022

The genomic landscape of tuberous sclerosis complex

por Martin, Katie R., Zhou, Wanding, Bowman, Megan J., Shih, Juliann, Au, Kit Sing, Dittenhafer-Reed, Kristin E., Sisson, Kellie A., Koeman, Julie, Weisenberger, Daniel J., Cottingham, Sandra L., DeRoos, Steven T., Devinsky, Orrin, Winn, Mary E., Cherniack, Andrew D., Shen, Hui, Northrup, Hope, Krueger, Darcy A., MacKeigan, Jeffrey P.
Publicado 2017