SHIVs, monkeys, and anti-HIV-1 neutralizing antibodies

por Martin, Malcolm A
Publicado 2013

The Simian Immunodeficiency Virus Targets Central Cell Cycle Functions through Transcriptional Repression In vivo

por Hogerkorp, Carl-Magnus, Nishimura, Yoshiaki, Song, Kaimei, Martin, Malcolm A., Roederer, Mario
Publicado 2011

Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor

por Nishimura, Yoshiaki, Francis, J. Nicholas, Donau, Olivia K., Jesteadt, Eric, Sadjadpour, Reza, Smith, Amanda R., Seaman, Michael S., Welch, Brett D., Martin, Malcolm A., Kay, Michael S.
Publicado 2020

The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4(+) Memory T Cells

por Shingai, Masashi, Welbourn, Sarah, Brenchley, Jason M., Acharya, Priyamvada, Miyagi, Eri, Plishka, Ronald J., Buckler-White, Alicia, Kwong, Peter D., Nishimura, Yoshiaki, Strebel, Klaus, Martin, Malcolm A.
Publicado 2015

A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection

por Gautam, Rajeev, Nishimura, Yoshiaki, Gaughan, Natalie, Gazumyan, Anna, Schoofs, Till, Buckler-White, Alicia, Seaman, Michael S., Swihart, Bruce J., Follmann, Dean A., Nussenzweig, Michel C., Martin, Malcolm A.
Publicado 2018

Immunotherapy during the acute SHIV infection of macaques confers long-term suppression of viremia

por Nishimura, Yoshiaki, Donau, Olivia K., Dias, Joana, Ferrando-Martinez, Sara, Jesteadt, Eric, Sadjadpour, Reza, Gautam, Rajeev, Buckler-White, Alicia, Geleziunas, Romas, Koup, Richard A., Nussenzweig, Michel C., Martin, Malcolm A.
Publicado 2020

Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope

por Abernathy, Morgan E., Gristick, Harry B., Vielmetter, Jost, Keeffe, Jennifer R., Gnanapragasam, Priyanthi N. P., Lee, Yu E., Escolano, Amelia, Gautam, Rajeev, Seaman, Michael S., Martin, Malcolm A., Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2021

Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer

por Yang, Zhi, Dam, Kim-Marie A., Bridges, Michael D., Hoffmann, Magnus A. G., DeLaitsch, Andrew T., Gristick, Harry B., Escolano, Amelia, Gautam, Rajeev, Martin, Malcolm A., Nussenzweig, Michel C., Hubbell, Wayne L., Bjorkman, Pamela J.
Publicado 2022

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections

por Wagh, Kshitij, Seaman, Michael S., Zingg, Marshall, Fitzsimons, Tomas, Barouch, Dan H., Burton, Dennis R., Connors, Mark, Ho, David D., Mascola, John R., Nussenzweig, Michel C., Ravetch, Jeffrey, Gautam, Rajeev, Martin, Malcolm A., Montefiori, David C., Korber, Bette
Publicado 2018

Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation and IL-17 production in the absence of SIV infect...

por Klatt, Nichole R., Harris, Levelle D., Vinton, Carol L., Sung, Hannah, Briant, Judith A., Tabb, Brian, Morcock, David, McGinty, John W., Lifson, Jeffrey D., Lafont, Bernard A., Martin, Malcolm A., Levine, Alan D., Estes, Jacob D., Brenchley, Jason M.
Publicado 2010

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

por Klein, Florian, Nogueira, Lilian, Nishimura, Yoshiaki, Phad, Ganesh, West, Anthony P., Halper-Stromberg, Ariel, Horwitz, Joshua A., Gazumyan, Anna, Liu, Cassie, Eisenreich, Thomas R., Lehmann, Clara, Fätkenheuer, Gerd, Williams, Constance, Shingai, Masashi, Martin, Malcolm A., Bjorkman, Pamela J., Seaman, Michael S., Zolla-Pazner, Susan, Karlsson Hedestam, Gunilla B., Nussenzweig, Michel C.
Publicado 2014

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

por Shingai, Masashi, Donau, Olivia K., Plishka, Ronald J., Buckler-White, Alicia, Mascola, John R., Nabel, Gary J., Nason, Martha C., Montefiori, David, Moldt, Brian, Poignard, Pascal, Diskin, Ron, Bjorkman, Pamela J., Eckhaus, Michael A., Klein, Florian, Mouquet, Hugo, Cetrulo Lorenzi, Julio Cesar, Gazumyan, Anna, Burton, Dennis R., Nussenzweig, Michel C., Martin, Malcolm A., Nishimura, Yoshiaki
Publicado 2014

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

por Doria-Rose, Nicole A., Altae-Tran, Han R., Roark, Ryan S., Schmidt, Stephen D., Sutton, Matthew S., Louder, Mark K., Chuang, Gwo-Yu, Bailer, Robert T., Cortez, Valerie, Kong, Rui, McKee, Krisha, O’Dell, Sijy, Wang, Felicia, Abdool Karim, Salim S., Binley, James M., Connors, Mark, Haynes, Barton F., Martin, Malcolm A., Montefiori, David C., Morris, Lynn, Overbaugh, Julie, Kwong, Peter D., Mascola, John R., Georgiev, Ivelin S.
Publicado 2017

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

por Francica, Joseph R., Sheng, Zizhang, Zhang, Zhenhai, Nishimura, Yoshiaki, Shingai, Masashi, Ramesh, Akshaya, Keele, Brandon F., Schmidt, Stephen D., Flynn, Barbara J., Darko, Sam, Lynch, Rebecca M., Yamamoto, Takuya, Matus-Nicodemos, Rodrigo, Wolinsky, David, Nason, Martha, Valiante, Nicholas M., Malyala, Padma, De Gregorio, Ennio, Barnett, Susan W., Singh, Manmohan, O'Hagan, Derek T., Koup, Richard A., Mascola, John R., Martin, Malcolm A., Kepler, Thomas B., Douek, Daniel C., Shapiro, Lawrence, Seder, Robert A.
Publicado 2015

Immunization expands HIV-1 V3-glycan specific B-cells in mice and macaques

por Escolano, Amelia, Gristick, Harry B., Abernathy, Morgan E., Merkenschlager, Julia, Gautam, Rajeev, Oliveira, Thiago Y., Pai, Joy, West, Anthony P., Barnes, Christopher O., Cohen, Alexander A., Wang, Haoqing, Golijanin, Jovana, Yost, Daniel, Keeffe, Jennifer R., Wang, Zijun, Zhao, Peng, Yao, Kai-Hui, Bauer, Jens, Nogueira, Lilian, Gao, Han, Voll, Alisa V., Montefiori, David C., Seaman, Michael S., Gazumyan, Anna, Silva, Murillo, McGuire, Andrew T., Stamatatos, Leonidas, Irvine, Darrell J., Wells, Lance, Martin, Malcolm A., Bjorkman, Pamela J., Nussenzweig, Michel C.
Publicado 2019