Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library

por Paul-Friedman, Katie, Martin, Matt, Crofton, Kevin M., Hsu, Chia-Wen, Sakamuru, Srilatha, Zhao, Jinghua, Xia, Menghang, Huang, Ruili, Stavreva, Diana A., Soni, Vikas, Varticovski, Lyuba, Raziuddin, Razi, Hager, Gordon L., Houck, Keith A.
Publicado 2019

Analysis of the Effects of Cell Stress and Cytotoxicity onIn Vitro Assay Activity Across a Diverse Chemical and Assay Space

por Judson, Richard, Houck, Keith, Martin, Matt, Richard, Ann M., Knudsen, Thomas B., Shah, Imran, Little, Stephen, Wambaugh, John, Setzer, R. Woodrow, Kothiya, Parth, Phuong, Jimmy, Filer, Dayne, Smith, Doris, Reif, David, Rotroff, Daniel, Kleinstreuer, Nicole, Sipes, Nisha, Xia, Menghang, Huang, Ruili, Crofton, Kevin, Thomas, Russell S.
Publicado 2016

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

por Huang, Ruili, Sakamuru, Srilatha, Martin, Matt T., Reif, David M., Judson, Richard S., Houck, Keith A., Casey, Warren, Hsieh, Jui-Hua, Shockley, Keith R., Ceger, Patricia, Fostel, Jennifer, Witt, Kristine L., Tong, Weida, Rotroff, Daniel M., Zhao, Tongan, Shinn, Paul, Simeonov, Anton, Dix, David J., Austin, Christopher P., Kavlock, Robert J., Tice, Raymond R., Xia, Menghang
Publicado 2014

Comparison of rat and rabbit embryo–fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

por Theunissen, Peter T., Beken, Sonja, Beyer, Bruce K., Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, De Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Hui, Julia Y., Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matt, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Publicado 2016