Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

por Nik-Zainal, Serena, Wedge, David C., Alexandrov, Ludmil B., Petljak, Mia, Butler, Adam P., Bolli, Niccolo, Davies, Helen R., Knappskog, Stian, Martin, Sancha, Papaemmanuil, Elli, Ramakrishna, Manasa, Shlien, Adam, Simonic, Ingrid, Xue, Yali, Tyler-Smith, Chris, Campbell, Peter J., Stratton, Michael R.
Publicado 2014

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

por Brinkman, Arie B., Nik-Zainal, Serena, Simmer, Femke, Rodríguez-González, F. Germán, Smid, Marcel, Alexandrov, Ludmil B., Butler, Adam, Martin, Sancha, Davies, Helen, Glodzik, Dominik, Zou, Xueqing, Ramakrishna, Manasa, Staaf, Johan, Ringnér, Markus, Sieuwerts, Anieta, Ferrari, Anthony, Morganella, Sandro, Fleischer, Thomas, Kristensen, Vessela, Gut, Marta, van de Vijver, Marc J., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Thomas, Gilles, Gut, Ivo G., Martens, John W. M., Foekens, John A., Stratton, Michael R., Stunnenberg, Hendrik G.
Publicado 2019

The SPECTRUM Consortium: a new UK Prevention Research Partnership consortium focussed on the commercial determinants of health, the prevention of non-communicable diseases, and the...

por Horton, Marie, Perman-Howe, Parvati R., Angus, Colin, Bishop, Julie, Bogdanovica, Ilze, Brennan, Alan, Britton, John, Brose, Leonie S., Brown, Jamie, Collin, Jeff, Dockrell, Martin, Fitzgerald, Niamh, Friel, Sharon, Gillespie, Duncan, Gilmore, Anna B., Hill, Sarah E., Knai, Cecile, Langley, Tessa, Martin, Sancha, McNeill, Ann, Moore, Graham, Munafò, Marcus R., Murray, Rachael L., Opazo Breton, Magdelena, Pearce, Jamie, Petticrew, Mark, Reid, Garth, Robson, Deborah, Rutter, Harry, Shahab, Lion, Shortt, Niamh, Smith, Katherine, Syrett, Keith, Bauld, Linda
Publicado 2021

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

por Behjati, Sam, Tarpey, Patrick S., Haase, Kerstin, Ye, Hongtao, Young, Matthew D., Alexandrov, Ludmil B., Farndon, Sarah J., Collord, Grace, Wedge, David C., Martincorena, Inigo, Cooke, Susanna L., Davies, Helen, Mifsud, William, Lidgren, Mathias, Martin, Sancha, Latimer, Calli, Maddison, Mark, Butler, Adam P., Teague, Jon W., Pillay, Nischalan, Shlien, Adam, McDermott, Ultan, Futreal, P. Andrew, Baumhoer, Daniel, Zaikova, Olga, Bjerkehagen, Bodil, Myklebost, Ola, Amary, M. Fernanda, Tirabosco, Roberto, Van Loo, Peter, Stratton, Michael R., Flanagan, Adrienne M., Campbell, Peter J.
Publicado 2017

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

por Yates, Lucy R, Gerstung, Moritz, Knappskog, Stian, Desmedt, Christine, Gundem, Gunes, Loo, Peter Van, Aas, Turid, Alexandrov, Ludmil B, Larsimont, Denis, Davies, Helen, Li, Yilong, Ju, Young Seok, Ramakrishna, Manasa, Haugland, Hans Kristian, Lilleng, Peer Kaare, Nik-Zainal, Serena, McLaren, Stuart, Butler, Adam, Martin, Sancha, Glodzik, Dominic, Menzies, Andrew, Raine, Keiran, Hinton, Jonathan, Jones, David, Mudie, Laura J, Jiang, Bing, Vincent, Delphine, Greene-Colozzi, April, Adnet, Pierre-Yves, Fatima, Aquila, Maetens, Marion, Ignatiadis, Michail, Stratton, Michael R, Sotiriou, Christos, Richardson, Andrea L, Lønning, Per Eystein, Wedge, David C, Campbell, Peter J
Publicado 2015

Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer

por Shlien, Adam, Raine, Keiran, Fuligni, Fabio, Arnold, Roland, Nik-Zainal, Serena, Dronov, Serge, Mamanova, Lira, Rosic, Andrej, Ju, Young Seok, Cooke, Susanna L., Ramakrishna, Manasa, Papaemmanuil, Elli, Davies, Helen R., Tarpey, Patrick S., Van Loo, Peter, Wedge, David C., Jones, David R., Martin, Sancha, Marshall, John, Anderson, Elizabeth, Hardy, Claire, Barbashina, Violetta, Aparicio, Samuel A.J.R., Sauer, Torill, Garred, Øystein, Vincent-Salomon, Anne, Mariani, Odette, Boyault, Sandrine, Fatima, Aquila, Langerød, Anita, Borg, Åke, Thomas, Gilles, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Polyak, Kornelia, Stratton, Michael R., Campbell, Peter J.
Publicado 2016

The topography of mutational processes in breast cancer genomes

por Morganella, Sandro, Alexandrov, Ludmil B., Glodzik, Dominik, Zou, Xueqing, Davies, Helen, Staaf, Johan, Sieuwerts, Anieta M., Brinkman, Arie B., Martin, Sancha, Ramakrishna, Manasa, Butler, Adam, Kim, Hyung-Yong, Borg, Åke, Sotiriou, Christos, Futreal, P. Andrew, Campbell, Peter J., Span, Paul N., Van Laere, Steven, Lakhani, Sunil R., Eyfjord, Jorunn E., Thompson, Alastair M., Stunnenberg, Hendrik G., van de Vijver, Marc J., Martens, John W. M., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles, Sale, Julian, Rada, Cristina, Stratton, Michael R., Birney, Ewan, Nik-Zainal, Serena
Publicado 2016

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

por Ferrari, Anthony, Vincent-Salomon, Anne, Pivot, Xavier, Sertier, Anne-Sophie, Thomas, Emilie, Tonon, Laurie, Boyault, Sandrine, Mulugeta, Eskeatnaf, Treilleux, Isabelle, MacGrogan, Gaëtan, Arnould, Laurent, Kielbassa, Janice, Le Texier, Vincent, Blanché, Hélène, Deleuze, Jean-François, Jacquemier, Jocelyne, Mathieu, Marie-Christine, Penault-Llorca, Frédérique, Bibeau, Frédéric, Mariani, Odette, Mannina, Cécile, Pierga, Jean-Yves, Trédan, Olivier, Bachelot, Thomas, Bonnefoi, Hervé, Romieu, Gilles, Fumoleau, Pierre, Delaloge, Suzette, Rios, Maria, Ferrero, Jean-Marc, Tarpin, Carole, Bouteille, Catherine, Calvo, Fabien, Gut, Ivo Glynne, Gut, Marta, Martin, Sancha, Nik-Zainal, Serena, Stratton, Michael R., Pauporté, Iris, Saintigny, Pierre, Birnbaum, Daniel, Viari, Alain, Thomas, Gilles
Publicado 2016

Processed pseudogenes acquired somatically during cancer development

por Cooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M.C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O’Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel, Munshi, Nikhil, Flanagan, Adrienne M., Bowtell, David, Martin, Sancha, Larsimont, Denis, Reis-Filho, Jorge S., Boussioutas, Alex, Taylor, Jack A., Hayes, Neil D., Janes, Sam M., Futreal, P. Andrew, Stratton, Michael R., McDermott, Ultan, Campbell, Peter J.
Publicado 2014

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

por Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B, Rahbari, Raheleh, Wedge, David C, Davies, Helen R, Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, Alder, Christopher, Patel, Nikita, Gamble, Steve, O’Meara, Sarah, Giri, Dilip D, Sauer, Torril, Pinder, Sarah E, Purdie, Colin A, Borg, Åke, Stunnenberg, Henk, van de Vijver, Marc, Tan, Benita K.T., Caldas, Carlos, Tutt, Andrew, Ueno, Naoto T, van’t Veer, Laura J, Martens, John W. M., Sotiriou, Christos, Knappskog, Stian, Span, Paul N., Lakhani, Sunil R., Eyfjörd, Jórunn Erla, Børresen-Dale, Anne-Lise, Richardson, Andrea, Thompson, Alastair M., Viari, Alain, Hurles, Matthew E, Nik-Zainal, Serena, Campbell, Peter J, Stratton, Michael R
Publicado 2017

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

por Behjati, Sam, Tarpey, Patrick S, Sheldon, Helen, Martincorena, Inigo, Van Loo, Peter, Gundem, Gunes, Wedge, David C, Ramakrishna, Manasa, Cooke, Susanna L, Pillay, Nischalan, Vollan, Hans Kristian M, Papaemmanuil, Elli, Koss, Hans, Bunney, Tom D, Hardy, Claire, Joseph, Olivia R, Martin, Sancha, Mudie, Laura, Butler, Adam, Teague, Jon W, Patil, Meena, Steers, Graham, Cao, Yu, Gumbs, Curtis, Ingram, Davis, Lazar, Alexander J, Little, Latasha, Mahadeshwar, Harshad, Protopopov, Alexei, Al Sannaa, Ghadah A, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Zhang, Jianhua, Ravi, Vinod, Torres, Keila E, Khatri, Bhavisha, Halai, Dina, Roxanis, Ioannis, Baumhoer, Daniel, Tirabosco, Roberto, Amary, M Fernanda, Boshoff, Chris, McDermott, Ultan, Katan, Matilda, Stratton, Michael R, Futreal, P Andrew, Flanagan, Adrienne M, Harris, Adrian, Campbell, Peter J
Publicado 2014

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

por Ju, Young Seok, Tubio, Jose M.C., Mifsud, William, Fu, Beiyuan, Davies, Helen R., Ramakrishna, Manasa, Li, Yilong, Yates, Lucy, Gundem, Gunes, Tarpey, Patrick S., Behjati, Sam, Papaemmanuil, Elli, Martin, Sancha, Fullam, Anthony, Gerstung, Moritz, Nangalia, Jyoti, Green, Anthony R., Caldas, Carlos, Borg, Åke, Tutt, Andrew, Lee, Ming Ta Michael, van't Veer, Laura J., Tan, Benita K.T., Aparicio, Samuel, Span, Paul N., Martens, John W.M., Knappskog, Stian, Vincent-Salomon, Anne, Børresen-Dale, Anne-Lise, Eyfjörd, Jórunn Erla, Flanagan, Adrienne M., Foster, Christopher, Neal, David E., Cooper, Colin, Eeles, Rosalind, Lakhani, Sunil R., Desmedt, Christine, Thomas, Gilles, Richardson, Andrea L., Purdie, Colin A., Thompson, Alastair M., McDermott, Ultan, Yang, Fengtang, Nik-Zainal, Serena, Campbell, Peter J., Stratton, Michael R.
Publicado 2015

The Life History of 21 Breast Cancers

por Nik-Zainal, Serena, Van Loo, Peter, Wedge, David C., Alexandrov, Ludmil B., Greenman, Christopher D., Lau, King Wai, Raine, Keiran, Jones, David, Marshall, John, Ramakrishna, Manasa, Shlien, Adam, Cooke, Susanna L., Hinton, Jonathan, Menzies, Andrew, Stebbings, Lucy A., Leroy, Catherine, Jia, Mingming, Rance, Richard, Mudie, Laura J., Gamble, Stephen J., Stephens, Philip J., McLaren, Stuart, Tarpey, Patrick S., Papaemmanuil, Elli, Davies, Helen R., Varela, Ignacio, McBride, David J., Bignell, Graham R., Leung, Kenric, Butler, Adam P., Teague, Jon W., Martin, Sancha, Jönsson, Goran, Mariani, Odette, Boyault, Sandrine, Miron, Penelope, Fatima, Aquila, Langerød, Anita, Aparicio, Samuel A.J.R., Tutt, Andrew, Sieuwerts, Anieta M., Borg, Åke, Thomas, Gilles, Salomon, Anne Vincent, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Publicado 2012

The circular RNome of primary breast cancer

por Smid, Marcel, Wilting, Saskia M., Uhr, Katharina, Rodríguez-González, F. Germán, de Weerd, Vanja, Prager-Van der Smissen, Wendy J.C., van der Vlugt-Daane, Michelle, van Galen, Anne, Nik-Zainal, Serena, Butler, Adam, Martin, Sancha, Davies, Helen R., Staaf, Johan, van de Vijver, Marc J., Richardson, Andrea L., MacGrogan, Gaëten, Salgado, Roberto, van den Eynden, Gert G.G.M., Purdie, Colin A., Thompson, Alastair M., Caldas, Carlos, Span, Paul N., Sweep, Fred C.G.J., Simpson, Peter T., Lakhani, Sunil R., Van Laere, Steven, Desmedt, Christine, Paradiso, Angelo, Eyfjord, Jorunn, Broeks, Annegien, Vincent-Salomon, Anne, Futreal, Andrew P., Knappskog, Stian, King, Tari, Viari, Alain, Børresen-Dale, Anne-Lise, Stunnenberg, Hendrik G., Stratton, Mike, Foekens, John A., Sieuwerts, Anieta M., Martens, John W.M.
Publicado 2019

Mutational Processes Molding the Genomes of 21 Breast Cancers

por Nik-Zainal, Serena, Alexandrov, Ludmil B., Wedge, David C., Van Loo, Peter, Greenman, Christopher D., Raine, Keiran, Jones, David, Hinton, Jonathan, Marshall, John, Stebbings, Lucy A., Menzies, Andrew, Martin, Sancha, Leung, Kenric, Chen, Lina, Leroy, Catherine, Ramakrishna, Manasa, Rance, Richard, Lau, King Wai, Mudie, Laura J., Varela, Ignacio, McBride, David J., Bignell, Graham R., Cooke, Susanna L., Shlien, Adam, Gamble, John, Whitmore, Ian, Maddison, Mark, Tarpey, Patrick S., Davies, Helen R., Papaemmanuil, Elli, Stephens, Philip J., McLaren, Stuart, Butler, Adam P., Teague, Jon W., Jönsson, Göran, Garber, Judy E., Silver, Daniel, Miron, Penelope, Fatima, Aquila, Boyault, Sandrine, Langerød, Anita, Tutt, Andrew, Martens, John W.M., Aparicio, Samuel A.J.R., Borg, Åke, Salomon, Anne Vincent, Thomas, Gilles, Børresen-Dale, Anne-Lise, Richardson, Andrea L., Neuberger, Michael S., Futreal, P. Andrew, Campbell, Peter J., Stratton, Michael R.
Publicado 2012

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

por Smid, Marcel, Rodríguez-González, F. Germán, Sieuwerts, Anieta M., Salgado, Roberto, Prager-Van der Smissen, Wendy J. C., Vlugt-Daane, Michelle van der, van Galen, Anne, Nik-Zainal, Serena, Staaf, Johan, Brinkman, Arie B., van de Vijver, Marc J., Richardson, Andrea L., Fatima, Aquila, Berentsen, Kim, Butler, Adam, Martin, Sancha, Davies, Helen R., Debets, Reno, Gelder, Marion E. Meijer-Van, van Deurzen, Carolien H. M., MacGrogan, Gaëtan, Van den Eynden, Gert G. G. M., Purdie, Colin, Thompson, Alastair M., Caldas, Carlos, Span, Paul N., Simpson, Peter T., Lakhani, Sunil R., Van Laere, Steven, Desmedt, Christine, Ringnér, Markus, Tommasi, Stefania, Eyford, Jorunn, Broeks, Annegien, Vincent-Salomon, Anne, Futreal, P. Andrew, Knappskog, Stian, King, Tari, Thomas, Gilles, Viari, Alain, Langerød, Anita, Børresen-Dale, Anne-Lise, Birney, Ewan, Stunnenberg, Hendrik G., Stratton, Mike, Foekens, John A., Martens, John W. M.
Publicado 2016

Signatures of mutational processes in human cancer

por Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A.J.R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolo, Borg, Ake, Børresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjörd, Jórunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinsk, Marcin, Jäger, Natalie, Jones, David T.W., Jones, David, Knappskog, Stian, Kool, Marcel, Lakhani, Sunil R., López-Otín, Carlos, Martin, Sancha, Munshi, Nikhil C., Nakamura, Hiromi, Northcott, Paul A., Pajic, Marina, Papaemmanuil, Elli, Paradiso, Angelo, Pearson, John V., Puente, Xose S., Raine, Keiran, Ramakrishna, Manasa, Richardson, Andrea L., Richter, Julia, Rosenstiel, Philip, Schlesner, Matthias, Schumacher, Ton N., Span, Paul N., Teague, Jon W., Totoki, Yasushi, Tutt, Andrew N.J., Valdés-Mas, Rafael, van Buuren, Marit M., van ’t Veer, Laura, Vincent-Salomon, Anne, Waddell, Nicola, Yates, Lucy R., Zucman-Rossi, Jessica, Futreal, P. Andrew, McDermott, Ultan, Lichter, Peter, Meyerson, Matthew, Grimmond, Sean M., Siebert, Reiner, Campo, Elías, Shibata, Tatsuhiro, Pfister, Stefan M., Campbell, Peter J., Stratton, Michael R.
Publicado 2013

Landscape of somatic mutations in 560 breast cancer whole genome sequences

por Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Young Seok, Smid, Marcel, Brinkman, Arie B, Morganella, Sandro, Aure, Miriam R., Lingjærde, Ole Christian, Langerød, Anita, Ringnér, Markus, Ahn, Sung-Min, Boyault, Sandrine, Brock, Jane E., Broeks, Annegien, Butler, Adam, Desmedt, Christine, Dirix, Luc, Dronov, Serge, Fatima, Aquila, Foekens, John A., Gerstung, Moritz, Hooijer, Gerrit KJ, Jang, Se Jin, Jones, David R., Kim, Hyung-Yong, King, Tari A., Krishnamurthy, Savitri, Lee, Hee Jin, Lee, Jeong-Yeon, Li, Yilong, McLaren, Stuart, Menzies, Andrew, Mustonen, Ville, O’Meara, Sarah, Pauporté, Iris, Pivot, Xavier, Purdie, Colin A., Raine, Keiran, Ramakrishnan, Kamna, Rodríguez-González, F. Germán, Romieu, Gilles, Sieuwerts, Anieta M., Simpson, Peter T, Shepherd, Rebecca, Stebbings, Lucy, Stefansson, Olafur A, Teague, Jon, Tommasi, Stefania, Treilleux, Isabelle, Van den Eynden, Gert G., Vermeulen, Peter, Vincent-Salomon, Anne, Yates, Lucy, Caldas, Carlos, van’t Veer, Laura, Tutt, Andrew, Knappskog, Stian, Tan, Benita Kiat Tee, Jonkers, Jos, Borg, Åke, Ueno, Naoto T, Sotiriou, Christos, Viari, Alain, Futreal, P. Andrew, Campbell, Peter J, Span, Paul N., Van Laere, Steven, Lakhani, Sunil R, Eyfjord, Jorunn E., Thompson, Alastair M., Birney, Ewan, Stunnenberg, Hendrik G, van de Vijver, Marc J, Martens, John W.M., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles, Stratton, Michael R.
Publicado 2016