Does human homology reduce the potential immunogenicity of non-antibody scaffolds?

por De Groot, Anne S., Khan, Sundos, Mattei, Aimee E., Lelias, Sandra, Martin, William D.
Publicado 2023

Development of a novel fully functional coagulation factor VIII with reduced immunogenicity utilizing an in silico prediction and deimmunization approach

por Winterling, Karina, Martin, William D., De Groot, Anne S., Daufenbach, Jens, Kistner, Steffen, Schüttrumpf, Jörg
Publicado 2021

Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

por He, Lu, De Groot, Anne S, Gutierrez, Andres H, Martin, William D, Moise, Lenny, Bailey-Kellogg, Chris
Publicado 2014

CHOPPI: A Web Tool for the Analysis of Immunogenicity Risk from Host Cell Proteins in CHO-Based Protein Production

por Bailey-Kellogg, Chris, Gutiérrez, Andres H, Moise, Leonard, Terry, Frances, Martin, William D, De Groot, Anne S
Publicado 2014

Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

por Gutiérrez, Andres H., Martin, William D., Bailey-Kellogg, Chris, Terry, Frances, Moise, Leonard, De Groot, Anne S.
Publicado 2015

Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction

por De Groot, Anne S., Skowron, Gail, White, James Robert, Boyle, Christine, Richard, Guilhem, Serreze, David, Martin, William D.
Publicado 2019

New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand

por Moise, Lenny, Gutiérrez, Andres H., Khan, Sundos, Tan, Swan, Ardito, Matt, Martin, William D., De Groot, Anne S.
Publicado 2020

Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

por Khan, Sundos, Parrillo, Matthew, Gutierrez, Andres H., Terry, Frances E., Moise, Leonard, Martin, William D., De Groot, Anne S.
Publicado 2019

In silico identification and modification of T cell epitopes in pertussis antigens associated with tolerance

por Kruiswijk, Corine, Richard, Guilhem, Salverda, Merijn L.M., Hindocha, Pooja, Martin, William D., De Groot, Anne S., Van Riet, Elly
Publicado 2020

Dendritic Cell-Mediated, DNA-Based Vaccination against Hepatitis C Induces the Multi-Epitope-Specific Response of Humanized, HLA Transgenic Mice

por Mishra, Sasmita, Lavelle, Bianca J., Desrosiers, Joe, Ardito, Matt T., Terry, Frances, Martin, William D., De Groot, Anne S., Gregory, Stephen H.
Publicado 2014

T‐cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin

por Gutiérrez, Andres H., Rapp‐Gabrielson, Vicki J., Terry, Frances E., Loving, Crystal L., Moise, Leonard, Martin, William D., De Groot, Anne S.
Publicado 2017

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance

por Liu, Rui, Moise, Leonard, Tassone, Ryan, Gutierrez, Andres H, Terry, Frances E, Sangare, Kotou, Ardito, Matthew T, Martin, William D, De Groot, Anne S
Publicado 2015

In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model

por Gutiérrez, Andres H., Loving, Crystal, Moise, Leonard, Terry, Frances E., Brockmeier, Susan L., Hughes, Holly R., Martin, William D., De Groot, Anne S.
Publicado 2016

Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection

por Moise, Leonard, Terry, Frances, Gutierrez, Andres H., Tassone, Ryan, Losikoff, Phyllis, Gregory, Stephen H., Bailey-Kellogg, Chris, Martin, William D., De Groot, Anne S.
Publicado 2014

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transge...

por Bounds, Callie E., Terry, Frances E., Moise, Leonard, Hannaman, Drew, Martin, William D., De Groot, Anne S., Suschak, John J., Dupuy, Lesley C., Schmaljohn, Connie S.
Publicado 2017

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

por Moise, Leonard, M. Biron, Bethany, Boyle, Christine M., Kurt Yilmaz, Nese, Jang, Hyesun, Schiffer, Celia, M. Ross, Ted, Martin, William D., De Groot, Anne S.
Publicado 2018

Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice

por Shattuck, Wendy M C, Dyer, Megan C, Desrosiers, Joe, Fast, Loren D, Terry, Frances E, Martin, William D, Moise, Leonard, De Groot, Anne S, Mather, Thomas N
Publicado 2014

Human Immune Responses to H. pylori HLA Class II Epitopes Identified by Immunoinformatic Methods

por Zhang, Songhua, Desrosiers, Joseph, Aponte-Pieras, Jose R., DaSilva, Kristen, Fast, Loren D., Terry, Frances, Martin, William D., De Groot, Anne S., Moise, Leonard, Moss, Steven F.
Publicado 2014

Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease

por De Groot, Anne S., Desai, Ankit K., Lelias, Sandra, Miah, S. M. Shahjahan, Terry, Frances E., Khan, Sundos, Li, Cindy, Yi, John S., Ardito, Matt, Martin, William D., Kishnani, Priya S.
Publicado 2021

Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

por Richard, Guilhem, De Groot, Anne S., Steinberg, Gary D., Garcia, Tzintzuni I., Kacew, Alec, Ardito, Matthew, Martin, William D., Berdugo, Gad, Princiotta, Michael F., Balar, Arjun V., Sweis, Randy F.
Publicado 2021