Virtual Screening Approaches towards the Discovery of Toll-Like Receptor Modulators

por Pérez-Regidor, Lucía, Zarioh, Malik, Ortega, Laura, Martín-Santamaría, Sonsoles
Publicado 2016

Computational Approaches to Toll-Like Receptor 4 Modulation

por Billod, Jean-Marc, Lacetera, Alessandra, Guzmán-Caldentey, Joan, Martín-Santamaría, Sonsoles
Publicado 2016

Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds

por Entova, Sonya, Billod, Jean-Marc, Swiecicki, Jean-Marie, Martín-Santamaría, Sonsoles, Imperiali, Barbara
Publicado 2018

Molecular Insight into the Regulation of Vimentin by Cysteine Modifications and Zinc Binding

por Mónico, Andreia, Guzmán-Caldentey, Joan, Pajares, María A., Martín-Santamaría, Sonsoles, Pérez-Sala, Dolores
Publicado 2021

Lipid-A-dependent and cholesterol-dependent dynamics properties of liposomes from gram-negative bacteria in ESKAPE

por Franco-Gonzalez, Juan Felipe, Matamoros-Recio, Alejandra, Torres-Mozas, Angel, Rodrigo-Lacave, Blanca, Martin-Santamaria, Sonsoles
Publicado 2022

Type IV Coupling Proteins as Potential Targets to Control the Dissemination of Antibiotic Resistance

por Álvarez-Rodríguez, Itxaso, Arana, Lide, Ugarte-Uribe, Begoña, Gómez-Rubio, Elena, Martín-Santamaría, Sonsoles, Garbisu, Carlos, Alkorta, Itziar
Publicado 2020

Understanding the Antibacterial Resistance: Computational Explorations in Bacterial Membranes

por Matamoros-Recio, Alejandra, Franco-Gonzalez, Juan Felipe, Forgione, Rosa Ester, Torres-Mozas, Angel, Silipo, Alba, Martín-Santamaría, Sonsoles
Publicado 2021

Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS

por Francisco, Sara, Billod, Jean-Marc, Merino, Javier, Punzón, Carmen, Gallego, Alicia, Arranz, Alicia, Martin-Santamaria, Sonsoles, Fresno, Manuel
Publicado 2022

New Therapeutic Strategies for Osteoarthritis by Targeting Sialic Acid Receptors

por Carpintero-Fernandez, Paula, Varela-Eirin, Marta, Lacetera, Alessandra, Gago-Fuentes, Raquel, Fonseca, Eduardo, Martin-Santamaria, Sonsoles, Mayan, Maria D.
Publicado 2020

Full‐Atom Model of the Agonist LPS‐Bound Toll‐like Receptor 4 Dimer in a Membrane Environment

por Matamoros‐Recio, Alejandra, Franco‐Gonzalez, Juan Felipe, Perez‐Regidor, Lucia, Billod, Jean‐Marc, Guzman‐Caldentey, Joan, Martin‐Santamaria, Sonsoles
Publicado 2021

Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance

por El-Halfawy, Omar M., Klett, Javier, Ingram, Rebecca J., Loutet, Slade A., Murphy, Michael E. P., Martín-Santamaría, Sonsoles, Valvano, Miguel A.
Publicado 2017

Enhancing Potency and Selectivity of a DC‐SIGN Glycomimetic Ligand by Fragment‐Based Design: Structural Basis

por Medve, Laura, Achilli, Silvia, Guzman‐Caldentey, Joan, Thépaut, Michel, Senaldi, Luca, Le Roy, Aline, Sattin, Sara, Ebel, Christine, Vivès, Corinne, Martin‐Santamaria, Sonsoles, Bernardi, Anna, Fieschi, Franck
Publicado 2019

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties

por Cochet, Florent, Facchini, Fabio A., Zaffaroni, Lenny, Billod, Jean-Marc, Coelho, Helena, Holgado, Aurora, Braun, Harald, Beyaert, Rudi, Jerala, Roman, Jimenez-Barbero, Jesus, Martin-Santamaria, Sonsoles, Peri, Francesco
Publicado 2019

Minimizing the Entropy Penalty for Ligand Binding: Lessons from the Molecular Recognition of the Histo Blood‐Group Antigens by Human Galectin‐3

por Gimeno, Ana, Delgado, Sandra, Valverde, Pablo, Bertuzzi, Sara, Berbís, Manuel Alvaro, Echavarren, Javier, Lacetera, Alessandra, Martín‐Santamaría, Sonsoles, Surolia, Avadhesha, Cañada, Francisco Javier, Jiménez‐Barbero, Jesus, Ardá, Ana
Publicado 2019

Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases

por Martin Merinero, Héctor, Subías, Marta, Pereda, Amaia, Gómez-Rubio, Elena, Juana Lopez, Lucia, Fernandez, Constantino, Goicoechea de Jorge, Elena, Martin-Santamaria, Sonsoles, Cañada, Francisco Javier, Rodríguez de Córdoba, Santiago
Publicado 2021

Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing

por Pérez-Regidor, Lucía, Guzmán-Caldentey, Joan, Oberhauser, Nils, Punzón, Carmen, Balogh, Balázs, Pedro, José R., Falomir, Eva, Nurisso, Alessandra, Mátyus, Péter, Menéndez, J. Carlos, de Andrés, Belén, Fresno, Manuel, Martín-Santamaría, Sonsoles
Publicado 2022

Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?

por Collado-Díaz, Víctor, Martinez-Cuesta, Maria Ángeles, Blanch-Ruiz, Maria Amparo, Sánchez-López, Ainhoa, García-Martínez, Patricia, Peris, José E, Usach, Iris, Ivorra, Maria Dolores, Lacetera, Alessandra, Martín-Santamaría, Sonsoles, Esplugues, Juan V., Alvarez, Angeles
Publicado 2021

Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity

por Facchini, Fabio A., Minotti, Alberto, Luraghi, Andrea, Romerio, Alessio, Gotri, Nicole, Matamoros-Recio, Alejandra, Iannucci, Andrea, Palmer, Charys, Wang, Guanbo, Ingram, Rebecca, Martin-Santamaria, Sonsoles, Pirianov, Grisha, De Andrea, Marco, Valvano, Miguel A., Peri, Francesco
Publicado 2021

Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10

por Forgione, Rosa Ester, Di Carluccio, Cristina, Guzmán-Caldentey, Juan, Gaglione, Rosa, Battista, Filomena, Chiodo, Fabrizio, Manabe, Yoshiyuki, Arciello, Angela, Del Vecchio, Pompea, Fukase, Koichi, Molinaro, Antonio, Martín-Santamaría, Sonsoles, Crocker, Paul R., Marchetti, Roberta, Silipo, Alba
Publicado 2020

Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10

por Forgione, Rosa Ester, Di Carluccio, Cristina, Guzmán-Caldentey, Juan, Gaglione, Rosa, Battista, Filomena, Chiodo, Fabrizio, Manabe, Yoshiyuki, Arciello, Angela, Del Vecchio, Pompea, Fukase, Koichi, Molinaro, Antonio, Martín-Santamaría, Sonsoles, Crocker, Paul R., Marchetti, Roberta, Silipo, Alba
Publicado 2020