Integration of constraint-based modeling with fecal metabolomics reveals large deleterious effects of Fusobacterium spp. on community butyrate production

por Hertel, Johannes, Heinken, Almut, Martinelli, Filippo, Thiele, Ines
Publicado 2021

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

por Heinken, Almut, Hertel, Johannes, Acharya, Geeta, Ravcheev, Dmitry A., Nyga, Malgorzata, Okpala, Onyedika Emmanuel, Hogan, Marcus, Magnúsdóttir, Stefanía, Martinelli, Filippo, Nap, Bram, Preciat, German, Edirisinghe, Janaka N., Henry, Christopher S., Fleming, Ronan M. T., Thiele, Ines
Publicado 2023

APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites

por Heinken, Almut, Hulshof, Timothy Otto, Nap, Bram, Martinelli, Filippo, Basile, Arianna, O'Brolchain, Amy, O’Sullivan, Neil Francis, Gallagher, Celine, Magee, Eimer, McDonagh, Francesca, Lalor, Ian, Bergin, Maeve, Evans, Phoebe, Daly, Rachel, Farrell, Ronan, Delaney, Rose Marie, Hill, Saoirse, McAuliffe, Saoirse Roisin, Kilgannon, Trevor, Fleming, Ronan M.T., Thinnes, Cyrille C., Thiele, Ines
Publicado 2023

Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease

por Martinelli, Filippo, Heinken, Almut, Henning, Ann-Kristin, Wörheide, Maria A., Hensen, Tim, González, Antonio, Arnold, Matthias, Asthana, Sanjay, Budde, Kathrin, Engelman, Corinne D., Estaki, Mehrbod, Grabe, Hans-Jörgen, Heston, Margo, Johnson, Sterling, Kastenmüller, Gabi, Martino, Cameron, McDonald, Daniel, Rey, Federico, Kilimann, Ingo, Peters, Olive, Wang, Xiao, Spruth, Eike Jakob, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, Glanz, Wenzel, Buerger, Katharina, Janowitz, Daniel, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Nauck, Matthias, Teipel, Stefan, Knight, Rob, Kaddurah-Daouk, Rima, Bendlin, Barbara B., Hertel, Johannes, Thiele, Ines
Publicado 2023