The promiscuous enzyme medium-chain 3-keto-acyl-CoA thiolase triggers a vicious cycle in fatty-acid beta-oxidation

por Martines, Anne-Claire M. F., van Eunen, Karen, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado 2017

Bistability in fatty-acid oxidation resulting from substrate inhibition

por Abegaz, Fentaw, Martines, Anne-Claire M. F., Vieira-Lara, Marcel A., Rios-Morales, Melany, Reijngoud, Dirk-Jan, Wit, Ernst C., Bakker, Barbara M.
Publicado 2021

Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients

por Odendaal, Christoff, Jager, Emmalie A., Martines, Anne-Claire M. F., Vieira-Lara, Marcel A., Huijkman, Nicolette C. A., Kiyuna, Ligia A., Gerding, Albert, Wolters, Justina C., Heiner-Fokkema, Rebecca, van Eunen, Karen, Derks, Terry G. J., Bakker, Barbara M.
Publicado 2023

Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD(+) in medium-chain acyl-CoA dehydrogenase knockout mice

por Martines, Anne-Claire M. F., Gerding, Albert, Stolle, Sarah, Vieira-Lara, Marcel A., Wolters, Justina C., Jurdzinski, Angelika, Bongiovanni, Laura, de Bruin, Alain, van der Vlies, Pieter, van der Vries, Gerben, Bloks, Vincent W., Derks, Terry G. J., Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado 2019

Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders

por van Eunen, Karen, Volker-Touw, Catharina M. L., Gerding, Albert, Bleeker, Aycha, Wolters, Justina C., van Rijt, Willemijn J., Martines, Anne-Claire M. F., Niezen-Koning, Klary E., Heiner, Rebecca M., Permentier, Hjalmar, Groen, Albert K., Reijngoud, Dirk-Jan, Derks, Terry G. J., Bakker, Barbara M.
Publicado 2016