Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer

por Huffman, Kenneth, Martinez, Elisabeth D.
Publicado 2013

A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells

por Huffman, Kenneth Edward, Carstens, Ryan, Martinez, Elisabeth D.
Publicado 2015

Unique epigenetic gene profiles define human breast cancers with poor prognosis

por Peña-Llopis, Samuel, Wan, Yihong, Martinez, Elisabeth D.
Publicado 2016

Epigenetic modulation reveals differentiation state specificity of oncogene addiction

por Khaliq, Mehwish, Manikkam, Mohan, Martinez, Elisabeth D., Fallahi-Sichani, Mohammad
Publicado 2021

Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay

por Best, Anne M., Chang, Jianjun, Dull, Angie B., Beutler, John A., Martinez, Elisabeth D.
Publicado 2011

2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity

por Wang, Lei, Kofler, Marina, Brosch, Gerald, Melesina, Jelena, Sippl, Wolfgang, Martinez, Elisabeth D., Easmon, Johnny
Publicado 2015

Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks

por Bayo, Juan, Tran, Tram Anh, Wang, Lei, Peña-Llopis, Samuel, Das, Amit K., Martinez, Elisabeth D.
Publicado 2018

γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers

por Trošt, Nuša, Peña-Llopis, Samuel, Koirala, Sajjan, Stojan, Jurij, Potts, Patrick Ryan, Tacer, Klementina Fon, Martinez, Elisabeth D.
Publicado 2015

Correction: γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers

por Trošt, Nuša, Peña-Llopis, Samuel, Koirala, Sajjan, Stojan, Jurij, Potts, Patrick Ryan, Fon Tacer, Klementina, Martinez, Elisabeth D.
Publicado 2019

Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival

por Tran, Tram Anh, Zhang, Qing-Jun, Wang, Lei, Gonzales, Christopher, Girard, Luc, May, Herman, Gillette, Thomas, Liu, Zhi-Ping, Martinez, Elisabeth D.
Publicado 2021

Identification of Small Molecule Modulators of Gene Transcription with Anticancer Activity

por Tran, Tram Anh, Wichterman-Kouznetsova, Jennifer, Varghese, Diana, Huang, Ruili, Huang, Wenwei, Becker, Matthias, Austin, Christopher P., Inglese, James, Johnson, Ronald L., Martinez, Elisabeth D.
Publicado 2014

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

por Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Publicado 2015

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

por Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Publicado 2015

Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity

por Cruz-Lorenzo, Emily, Ramirez, Nora-Guadalupe P., Lee, Jeon, Pandhe, Sonali, Wang, Lei, Hernandez-Doria, Juan, Spivak, Adam M., Planelles, Vicente, Petersen, Tianna, Jain, Mamta K., Martinez, Elisabeth D., D’Orso, Iván
Publicado 2022

Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases

por Matthews, Krista A., Senagbe, Kossi M., Nötzel, Christopher, Gonzales, Christopher A., Tong, Xinran, Rijo-Ferreira, Filipa, Bhanu, Natarajan V., Miguel-Blanco, Celia, Lafuente-Monasterio, Maria Jose, Garcia, Benjamin A., Kafsack, Björn F. C., Martinez, Elisabeth D.
Publicado 2020

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth

por Wang, Lei, Chang, Jianjun, Varghese, Diana, Dellinger, Michael, Kumar, Subodh, Best, Anne M., Ruiz, Julio, Bruick, Richard, Peña-Llopis, Samuel, Xu, Junjie, Babinski, David J., Frantz, Doug E., Brekken, Rolf A., Quinn, Amy M., Simeonov, Anton, Easmon, Johnny, Martinez, Elisabeth D.
Publicado 2013

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

por Zhang, Qing-Jun, Tran, Tram Anh T., Wang, Ming, Ranek, Mark J., Kokkonen-Simon, Kristen M., Gao, Jason, Luo, Xiang, Tan, Wei, Kyrychenko, Viktoriia, Liao, Lan, Xu, Jianming, Hill, Joseph A., Olson, Eric N., Kass, David A., Martinez, Elisabeth D., Liu, Zhi-Ping
Publicado 2018

Telomerase-Mediated Strategy for Overcoming Non–Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance

por Mender, Ilgen, LaRanger, Ryan, Luitel, Krishna, Peyton, Michael, Girard, Luc, Lai, Tsung-Po, Batten, Kimberly, Cornelius, Crystal, Dalvi, Maithili P., Ramirez, Michael, Du, Wenting, Wu, Lani F., Altschuler, Steven J., Brekken, Rolf, Martinez, Elisabeth D., Minna, John D., Wright, Woodring E., Shay, Jerry W.
Publicado 2018

Assessing histone demethylase inhibitors in cells: lessons learned

por Hatch, Stephanie B., Yapp, Clarence, Montenegro, Raquel C., Savitsky, Pavel, Gamble, Vicki, Tumber, Anthony, Ruda, Gian Filippo, Bavetsias, Vassilios, Fedorov, Oleg, Atrash, Butrus, Raynaud, Florence, Lanigan, Rachel, Carmichael, LeAnne, Tomlin, Kathy, Burke, Rosemary, Westaway, Susan M., Brown, Jack A., Prinjha, Rab K., Martinez, Elisabeth D., Oppermann, Udo, Schofield, Christopher J., Bountra, Chas, Kawamura, Akane, Blagg, Julian, Brennan, Paul E., Rossanese, Olivia, Müller, Susanne
Publicado 2017

JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis

por Son, Juhee, Huang, Shimeng, Zeng, Qiru, Bricker, Traci L., Case, James Brett, Zhou, Jinzhu, Zang, Ruochen, Liu, Zhuoming, Chang, Xinjian, Harastani, Houda H., Chen, Lu, Castro, Maria Florencia Gomez, Zhao, Yongxiang, Kohio, Hinissan P., Hou, Gaopeng, Fan, Baochao, Niu, Beibei, Guo, Rongli, Rothlauf, Paul W., Bailey, Adam L., Wang, Xin, Shi, Pei-Yong, Martinez, Elisabeth D., Whelan, Sean P.J., Diamond, Michael S., Boon, Adrianus C.M., Li, Bin, Ding, Siyuan
Publicado 2021