Unglycosylated Soluble SARS-CoV-2 Receptor Binding Domain (RBD) Produced in E. coli Combined with the Army Liposomal Formulation Containing QS21 (ALFQ) Elicits Neutralizing Antibod...

por Balasubramaniyam, Arasu, Ryan, Emma, Brown, Dallas, Hamza, Therwa, Harrison, William, Gan, Michael, Sankhala, Rajeshwer S., Chen, Wei-Hung, Martinez, Elizabeth J., Jensen, Jaime L., Dussupt, Vincent, Mendez-Rivera, Letzibeth, Mayer, Sandra, King, Jocelyn, Michael, Nelson L., Regules, Jason, Krebs, Shelly, Rao, Mangala, Matyas, Gary R., Joyce, M. Gordon, Batchelor, Adrian H., Gromowski, Gregory D., Dutta, Sheetij
Publicado 2022

Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity

por Jensen, Jaime L., Sankhala, Rajeshwer S., Dussupt, Vincent, Bai, Hongjun, Hajduczki, Agnes, Lal, Kerri G., Chang, William C., Martinez, Elizabeth J., Peterson, Caroline E., Golub, Emily S., Rees, Phyllis A., Mendez-Rivera, Letzibeth, Zemil, Michelle, Kavusak, Erin, Mayer, Sandra V., Wieczorek, Lindsay, Kannan, Shruthi, Doranz, Benjamin J., Davidson, Edgar, Yang, Eun Sung, Zhang, Yi, Chen, Man, Choe, Misook, Wang, Lingshu, Gromowski, Gregory D., Koup, Richard A., Michael, Nelson L., Polonis, Victoria R., Rolland, Morgane, Modjarrad, Kayvon, Krebs, Shelly J., Joyce, M. Gordon
Publicado 2023

Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques

por Yu, Jingyou, Thomas, Paul V., Sciacca, Michaela, Wu, Cindy, Liu, Jinyan, He, Xuan, Miller, Jessica, Hachmann, Nicole P., Surve, Nehalee, McMahan, Katherine, Jacob-Dolan, Catherine, Powers, Olivia, Hall, Kevin, Barrett, Julia, Hope, David, Mazurek, Camille R., Murdza, Tetyana, Chang, William C., Golub, Emily, Rees, Phyllis A., Peterson, Caroline E., Hajduczki, Agnes, Chen, Wei-Hung, Martinez, Elizabeth J., Hussin, Elizabeth, Lange, Camille, Gong, Hua, Matyas, Gary R., Rao, Mangala, Suthar, Mehul, Boursiquot, Mona, Cook, Anthony, Pessaint, Laurent, Lewis, Mark G., Andersen, Hanne, Bolton, Diane L., Michael, Nelson L., Joyce, M. Gordon, Modjarrad, Kayvon, Barouch, Dan H.
Publicado 2023

Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN

por Yu, Jingyou, Thomas, Paul V., McMahan, Katherine, Jacob-Dolan, Catherine, Liu, Jinyan, He, Xuan, Hope, David, Martinez, Elizabeth J., Chen, Wei-Hung, Sciacca, Michaela, Hachmann, Nicole P., Lifton, Michelle, Miller, Jessica, Powers, Olivia C., Hall, Kevin, Wu, Cindy, Barrett, Julia, Swafford, Isabella, Currier, Jeffrey R., King, Jocelyn, Corbitt, Courtney, Chang, William C., Golub, Emily, Rees, Phyllis A., Peterson, Caroline E., Hajduczki, Agnes, Hussin, Elizabeth, Lange, Camille, Gong, Hua, Matyas, Gary R., Rao, Mangala, Paquin-Proulx, Dominic, Gromowski, Gregory D., Lewis, Mark G., Andersen, Hanne, Davis-Gardner, Meredith, Suthar, Mehul S., Michael, Nelson L., Bolton, Diane L., Joyce, M. Gordon, Modjarrad, Kayvon, Barouch, Dan H.
Publicado 2022

Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity

por Chen, Wei-Hung, Hajduczki, Agnes, Martinez, Elizabeth J., Bai, Hongjun, Matz, Hanover, Hill, Thomas M., Lewitus, Eric, Chang, William C., Dawit, Layla, Peterson, Caroline E., Rees, Phyllis A., Ajayi, Adelola B., Golub, Emily S., Swafford, Isabella, Dussupt, Vincent, David, Sapna, Mayer, Sandra V., Soman, Sandrine, Kuklis, Caitlin, Corbitt, Courtney, King, Jocelyn, Choe, Misook, Sankhala, Rajeshwer S., Thomas, Paul V., Zemil, Michelle, Wieczorek, Lindsay, Hart, Tricia, Duso, Debora, Kummer, Larry, Yan, Lianying, Sterling, Spencer L., Laing, Eric D., Broder, Christopher C., Williams, Jazmean K., Davidson, Edgar, Doranz, Benjamin J., Krebs, Shelly J., Polonis, Victoria R., Paquin-Proulx, Dominic, Rolland, Morgane, Reiley, William W., Gromowski, Gregory D., Modjarrad, Kayvon, Dooley, Helen, Joyce, M. Gordon
Publicado 2023

A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model

por Johnston, Sara C., Ricks, Keersten M., Lakhal-Naouar, Ines, Jay, Alexandra, Subra, Caroline, Raymond, Jo Lynne, King, Hannah A. D., Rossi, Franco, Clements, Tamara L., Fetterer, David, Tostenson, Samantha, Cincotta, Camila Macedo, Hack, Holly R., Kuklis, Caitlin, Soman, Sandrine, King, Jocelyn, Peachman, Kristina K., Kim, Dohoon, Chen, Wei-Hung, Sankhala, Rajeshwer S., Martinez, Elizabeth J., Hajduczki, Agnes, Chang, William C., Choe, Misook, Thomas, Paul V., Peterson, Caroline E., Anderson, Alexander, Swafford, Isabella, Currier, Jeffrey R., Paquin-Proulx, Dominic, Jagodzinski, Linda L., Matyas, Gary R., Rao, Mangala, Gromowski, Gregory D., Peel, Sheila A., White, Lauren, Smith, Jeffrey M., Hooper, Jay W., Michael, Nelson L., Modjarrad, Kayvon, Joyce, M. Gordon, Nalca, Aysegul, Bolton, Diane L., Pitt, Margaret L. M.
Publicado 2022

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

por Dussupt, Vincent, Sankhala, Rajeshwer S., Mendez-Rivera, Letzibeth, Townsley, Samantha M., Schmidt, Fabian, Wieczorek, Lindsay, Lal, Kerri G., Donofrio, Gina C., Tran, Ursula, Jackson, Nathaniel D., Zaky, Weam I., Zemil, Michelle, Tritsch, Sarah R., Chen, Wei-Hung, Martinez, Elizabeth J., Ahmed, Aslaa, Choe, Misook, Chang, William C., Hajduczki, Agnes, Jian, Ningbo, Peterson, Caroline E., Rees, Phyllis A., Rutkowska, Magdalena, Slike, Bonnie M., Selverian, Christopher N., Swafford, Isabella, Teng, I-Ting, Thomas, Paul V., Zhou, Tongqing, Smith, Clayton J., Currier, Jeffrey R., Kwong, Peter D., Rolland, Morgane, Davidson, Edgar, Doranz, Benjamin J., Mores, Christopher N., Hatziioannou, Theodora, Reiley, William W., Bieniasz, Paul D., Paquin-Proulx, Dominic, Gromowski, Gregory D., Polonis, Victoria R., Michael, Nelson L., Modjarrad, Kayvon, Joyce, M. Gordon, Krebs, Shelly J.
Publicado 2021

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters

por Wuertz, Kathryn McGuckin, Barkei, Erica K., Chen, Wei-Hung, Martinez, Elizabeth J., Lakhal-Naouar, Ines, Jagodzinski, Linda L., Paquin-Proulx, Dominic, Gromowski, Gregory D., Swafford, Isabella, Ganesh, Akshaya, Dong, Ming, Zeng, Xiankun, Thomas, Paul V., Sankhala, Rajeshwer S., Hajduczki, Agnes, Peterson, Caroline E., Kuklis, Caitlin, Soman, Sandrine, Wieczorek, Lindsay, Zemil, Michelle, Anderson, Alexander, Darden, Janice, Hernandez, Heather, Grove, Hannah, Dussupt, Vincent, Hack, Holly, de la Barrera, Rafael, Zarling, Stasya, Wood, James F., Froude, Jeffrey W., Gagne, Matthew, Henry, Amy R., Mokhtari, Elham Bayat, Mudvari, Prakriti, Krebs, Shelly J., Pekosz, Andrew S., Currier, Jeffrey R., Kar, Swagata, Porto, Maciel, Winn, Adrienne, Radzyminski, Kamil, Lewis, Mark G., Vasan, Sandhya, Suthar, Mehul, Polonis, Victoria R., Matyas, Gary R., Boritz, Eli A., Douek, Daniel C., Seder, Robert A., Daye, Sharon P., Rao, Mangala, Peel, Sheila A., Joyce, M. Gordon, Bolton, Diane L., Michael, Nelson L., Modjarrad, Kayvon
Publicado 2021

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge

por Wuertz, Kathryn McGuckin, Barkei, Erica K., Chen, Wei-Hung, Martinez, Elizabeth J., Lakhal-Naouar, Ines, Jagodzinski, Linda L., Paquin-Proulx, Dominic, Gromowski, Gregory D., Swafford, Isabella, Ganesh, Akshaya, Dong, Ming, Zeng, Xiankun, Thomas, Paul V., Sankhala, Rajeshwer S., Hajduczki, Agnes, Peterson, Caroline E., Kuklis, Caitlin, Soman, Sandrine, Wieczorek, Lindsay, Zemil, Michelle, Anderson, Alexander, Darden, Janice, Hernandez, Heather, Grove, Hannah, Dussupt, Vincent, Hack, Holly, de la Barrera, Rafael, Zarling, Stasya, Wood, James F., Froude, Jeffrey W., Gagne, Matthew, Henry, Amy R., Mokhtari, Elham Bayat, Mudvari, Prakriti, Krebs, Shelly J., Pekosz, Andrew S., Currier, Jeffrey R., Kar, Swagata, Porto, Maciel, Winn, Adrienne, Radzyminski, Kamil, Lewis, Mark G., Vasan, Sandhya, Suthar, Mehul, Polonis, Victoria R., Matyas, Gary R., Boritz, Eli A., Douek, Daniel C., Seder, Robert A., Daye, Sharon P., Rao, Mangala, Peel, Sheila A., Joyce, M. Gordon, Bolton, Diane L., Michael, Nelson L., Modjarrad, Kayvon
Publicado 2021

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

por King, Hannah A. D., Joyce, M. Gordon, Lakhal-Naouar, Ines, Ahmed, Aslaa, Cincotta, Camila Macedo, Subra, Caroline, Peachman, Kristina K., Hack, Holly R., Chen, Rita E., Thomas, Paul V., Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Martinez, Elizabeth J., Peterson, Caroline E., Chang, William C., Choe, Misook, Smith, Clayton, Headley, Jarrett A., Elyard, Hanne A., Cook, Anthony, Anderson, Alexander, Wuertz, Kathryn McGuckin, Dong, Ming, Swafford, Isabella, Case, James B., Currier, Jeffrey R., Lal, Kerri G., Amare, Mihret F., Dussupt, Vincent, Molnar, Sebastian, Daye, Sharon P., Zeng, Xiankun, Barkei, Erica K., Alfson, Kendra, Staples, Hilary M., Carrion, Ricardo, Krebs, Shelly J., Paquin-Proulx, Dominic, Karasavvas, Nicos, Polonis, Victoria R., Jagodzinski, Linda L., Vasan, Sandhya, Scott, Paul T., Huang, Yaoxing, Nair, Manoj S., Ho, David D., de Val, Natalia, Diamond, Michael S., Lewis, Mark G., Rao, Mangala, Matyas, Gary R., Gromowski, Gregory D., Peel, Sheila A., Michael, Nelson L., Modjarrad, Kayvon, Bolton, Diane L.
Publicado 2021

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

por Joyce, M. Gordon, Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Thomas, Paul V., Choe, Misook, Martinez, Elizabeth J., Chang, William C., Peterson, Caroline E., Morrison, Elaine B., Smith, Clayton, Chen, Rita E., Ahmed, Aslaa, Wieczorek, Lindsay, Anderson, Alexander, Case, James Brett, Li, Yifan, Oertel, Therese, Rosado, Lorean, Ganesh, Akshaya, Whalen, Connor, Carmen, Joshua M., Mendez-Rivera, Letzibeth, Karch, Christopher P., Gohain, Neelakshi, Villar, Zuzana, McCurdy, David, Beck, Zoltan, Kim, Jiae, Shrivastava, Shikha, Jobe, Ousman, Dussupt, Vincent, Molnar, Sebastian, Tran, Ursula, Kannadka, Chandrika B., Soman, Sandrine, Kuklis, Caitlin, Zemil, Michelle, Khanh, Htet, Wu, Weimin, Cole, Matthew A., Duso, Debra K., Kummer, Larry W., Lang, Tricia J., Muncil, Shania E., Currier, Jeffrey R., Krebs, Shelly J., Polonis, Victoria R., Rajan, Saravanan, McTamney, Patrick M., Esser, Mark T., Reiley, William W., Rolland, Morgane, de Val, Natalia, Diamond, Michael S., Gromowski, Gregory D., Matyas, Gary R., Rao, Mangala, Michael, Nelson L., Modjarrad, Kayvon
Publicado 2021