HIV-1 reverse transcriptase complex with DNA and nevirapine reveals nonnucleoside inhibition mechanism

por Das, Kalyan, Martinez, Sergio E., Bauman, Joseph D., Arnold, Eddy
Publicado 2012

Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage

por Das, Kalyan, Martinez, Sergio E., Bandwar, Rajiv P., Arnold, Eddy
Publicado 2014

Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation

por Das, Kalyan, Martinez, Sergio E., DeStefano, Jeffrey J., Arnold, Eddy
Publicado 2019

Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket – targeting P-pocket by fragment screening

por Singh, Abhimanyu K., Martinez, Sergio E., Gu, Weijie, Nguyen, Hoai, Schols, Dominique, Herdewijn, Piet, De Jonghe, Steven, Das, Kalyan
Publicado 2021

Assembly and Cryo-EM structure determination of yeast mitochondrial RNA polymerase initiation complex intermediates

por Martinez, Sergio E., Singh, Anupam, De Wijngaert, Brent, Sultana, Shemaila, Dharia, Chhaya, Vanbuel, Hans, Shen, Jiayu, Vasilchuk, Daniel, Patel, Smita S., Das, Kalyan
Publicado 2021

Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine

por Singh, Abhimanyu K., De Wijngaert, Brent, Bijnens, Marc, Uyttersprot, Kris, Nguyen, Hoai, Martinez, Sergio E., Schols, Dominique, Herdewijn, Piet, Pannecouque, Christophe, Arnold, Eddy, Das, Kalyan
Publicado 2022