Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons

por Martinez, Terina N, Chen, Xi, Bandyopadhyay, Sibali, Merrill, Alfred H, Tansey, Malú G
Publicado 2012

Transforming Drug Development for Neurological Disorders: Proceedings from a Multidisease Area Workshop

por Stephenson, Diane, Belfiore-Oshan, Ramona, Karten, Yashmin, Keavney, Jessi, Kwok, D. Kevin, Martinez, Terina, Montminy, Joe, Müller, Martijn L. T. M., Romero, Klaus, Sivakumaran, Sudhir
Publicado 2023

Correction: Transforming Drug Development for Neurological Disorders: Proceedings from a Multidisease Area Workshop

por Stephenson, Diane, Belfiore-Oshan, Ramona, Karten, Yashmin, Keavney, Jessi, Kwok, D. Kevin, Martinez, Terina, Montminy, Joe, Müller, Martijn L. T. M., Romero, Klaus, Sivakumaran, Sudhir
Publicado 2023

Rab29 activation of the Parkinson's disease‐associated LRRK2 kinase

por Purlyte, Elena, Dhekne, Herschel S, Sarhan, Adil R, Gomez, Rachel, Lis, Pawel, Wightman, Melanie, Martinez, Terina N, Tonelli, Francesca, Pfeffer, Suzanne R, Alessi, Dario R
Publicado 2017

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(−/−) mice

por Nguyen, Thi A, Frank-Cannon, Tamy, Martinez, Terina N, Ruhn, Kelly A, Marvin, Marian, Casey, Bradford, Treviño, Isaac, Hong, John J, Goldberg, Matthew S, Tansey, Malú G
Publicado 2013

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

por Fan, Ying, Howden, Andrew J.M., Sarhan, Adil R., Lis, Pawel, Ito, Genta, Martinez, Terina N., Brockmann, Kathrin, Gasser, Thomas, Alessi, Dario R., Sammler, Esther M.
Publicado 2018

The hTH-GFP Reporter Rat Model for the Study of Parkinson's Disease

por Iacovitti, Lorraine, Wei, Xiaotao, Cai, Jingli, Kostuk, Eric W., Lin, Ruihe, Gorodinsky, Alexander, Roman, Philip, Kusek, Gretchen, Das, Sonal S., Dufour, Audrey, Martinez, Terina N., Dave, Kuldip D.
Publicado 2014

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis

por Steger, Martin, Diez, Federico, Dhekne, Herschel S, Lis, Pawel, Nirujogi, Raja S, Karayel, Ozge, Tonelli, Francesca, Martinez, Terina N, Lorentzen, Esben, Pfeffer, Suzanne R, Alessi, Dario R, Mann, Matthias
Publicado 2017

Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

por Polinski, Nicole K., Volpicelli-Daley, Laura A., Sortwell, Caryl E., Luk, Kelvin C., Cremades, Nunilo, Gottler, Lindsey M., Froula, Jessica, Duffy, Megan F., Lee, Virginia M.Y., Martinez, Terina N., Dave, Kuldip D.
Publicado 2018

The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models

por Polinski, Nicole K., Martinez, Terina N., Ramboz, Sylvie, Sasner, Michael, Herberth, Mark, Switzer, Robert, Ahmad, Syed O., Pelligrino, Lee J., Clark, Sean W., Marcus, Jacob N., Smith, Sean M., Dave, Kuldip D., Frasier, Mark A.
Publicado 2022

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human

por Mir, Rafeeq, Tonelli, Francesca, Lis, Pawel, Macartney, Thomas, Polinski, Nicole K., Martinez, Terina N., Chou, Meng-Yun, Howden, Andrew J.M., König, Theresa, Hotzy, Christoph, Milenkovic, Ivan, Brücke, Thomas, Zimprich, Alexander, Sammler, Esther, Alessi, Dario R.
Publicado 2018

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase

por Lis, Pawel, Burel, Sophie, Steger, Martin, Mann, Matthias, Brown, Fiona, Diez, Federico, Tonelli, Francesca, Holton, Janice L., Ho, Philip Winglok, Ho, Shu-Leong, Chou, Meng-Yun, Polinski, Nicole K., Martinez, Terina N., Davies, Paul, Alessi, Dario R.
Publicado 2018

Multivariate modeling of magnetic resonance biomarkers and clinical outcome measures for Duchenne muscular dystrophy clinical trials

por Kim, Sarah, Willcocks, Rebecca J., Daniels, Michael J., Morales, Juan Francisco, Yoon, Deok Yong, Triplett, William T., Barnard, Alison M., Conrado, Daniela J., Aggarwal, Varun, Belfiore‐Oshan, Ramona, Martinez, Terina N., Walter, Glenn A., Rooney, William D., Vandenborne, Krista
Publicado 2023

Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model

por Polinski, Nicole K., Martinez, Terina N., Gorodinsky, Alexander, Gareus, Ralph, Sasner, Michael, Herberth, Mark, Switzer, Robert, Ahmad, Syed O., Cosden, Mali, Kandebo, Monika, Drolet, Robert E., Buckett, Peter D., Shan, Weisong, Chen, Yi, Pellegrino, Lee J., Ellsworth, Gregory D., Dungan, Leo B., Hirst, Warren D., Clark, Sean W., Dave, Kuldip D.
Publicado 2021