Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family

por Amrhein, Jennifer Alisa, Berger, Lena Marie, Tjaden, Amelie, Krämer, Andreas, Elson, Lewis, Tolvanen, Tuomas, Martinez-Molina, Daniel, Kaiser, Astrid, Schubert-Zsilavecz, Manfred, Müller, Susanne, Knapp, Stefan, Hanke, Thomas
Publicado 2022

Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

por Shaw, Joseph, Dale, Ian, Hemsley, Paul, Leach, Lindsey, Dekki, Nancy, Orme, Jonathan P., Talbot, Verity, Narvaez, Ana J., Bista, Michal, Martinez Molina, Daniel, Dabrowski, Michael, Main, Martin J., Gianni, Davide
Publicado 2018

Cellular Active N-Hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site

por Exell, Jack C., Thompson, Mark J., Finger, L. David, Shaw, Steven J., Debreczeni, Judit, Ward, Thomas A., McWhirter, Claire, Siöberg, Catrine L. B., Martinez Molina, Daniel, Mark Abbott, W., Jones, Clifford D., Nissink, J. Willem M., Durant, Stephen T., Grasby, Jane A.
Publicado 2016