Identifying cytokine signaling signatures in primary human Th-1 cells by phospho-proteomics analysis

por Martinez-Fabregas, Jonathan, Pohler, Elizabeth, Moraga, Ignacio
Publicado 2021

Mapping Determinants of Cytokine Signaling via Protein Engineering

por Gorby, Claire, Martinez-Fabregas, Jonathan, Wilmes, Stephan, Moraga, Ignacio
Publicado 2018

Lysosomes: multifunctional compartments ruled by a complex regulatory network

por Martinez‐Fabregas, Jonathan, Tamargo‐Azpilicueta, Joaquin, Diaz‐Moreno, Irene
Publicado 2022

CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci

por Martinez-Fabregas, Jonathan, Wang, Luopin, Pohler, Elizabeth, Cozzani, Adeline, Wilmes, Stephan, Kazemian, Majid, Mitra, Suman, Moraga, Ignacio
Publicado 2020

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

por Martínez-Fábregas, Jonathan, Prescott, Alan, van Kasteren, Sander, Pedrioli, Deena Leslie, McLean, Irwin, Moles, Anna, Reinheckel, Thomas, Poli, Valeria, Watts, Colin
Publicado 2018

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

por Martinez-Fabregas, Jonathan, Wilmes, Stephan, Wang, Luopin, Hafer, Maximillian, Pohler, Elizabeth, Lokau, Juliane, Garbers, Christoph, Cozzani, Adeline, Fyfe, Paul K, Piehler, Jacob, Kazemian, Majid, Mitra, Suman, Moraga, Ignacio
Publicado 2019

Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses

por Wilmes, Stephan, Jeffrey, Polly-Anne, Martinez-Fabregas, Jonathan, Hafer, Maximillian, Fyfe, Paul K, Pohler, Elizabeth, Gaggero, Silvia, López-García, Martín, Lythe, Grant, Taylor, Charles, Guerrier, Thomas, Launay, David, Mitra, Suman, Piehler, Jacob, Molina-París, Carmen, Moraga, Ignacio
Publicado 2021