Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome

por Andrews, Elizabeth J., Martini, Alessandra C., Head, Elizabeth
Publicado 2022

Aging in Down Syndrome: Latest Clinical Advances and Prospects

por Martini, Alessandra C., Alldred, Melissa J., Granholm, Ann-Charlotte
Publicado 2021

Reply to Peng and Zhao: Loss of endocytic protein TOM1 in Alzheimer’s disease

por Martini, Alessandra C., Baglietto-Vargas, David, Medeiros, Rodrigo, LaFerla, Frank M.
Publicado 2020

Aging with Down Syndrome—Where Are We Now and Where Are We Going?

por Alldred, Melissa J., Martini, Alessandra C., Patterson, David, Hendrix, James, Granholm, Ann-Charlotte
Publicado 2021

Neuropathology of Aging in Cats and its Similarities to Human Alzheimer’s Disease

por Sordo, Lorena, Martini, Alessandra C., Houston, E. Fiona, Head, Elizabeth, Gunn-Moore, Danièlle
Publicado 2021

Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

por Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Publicado 2020

miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease

por Rodriguez‐Ortiz, Carlos J., Prieto, Gilberto Aleph, Martini, Alessandra C., Forner, Stefania, Trujillo‐Estrada, Laura, LaFerla, Frank M., Baglietto‐Vargas, David, Cotman, Carl W., Kitazawa, Masashi
Publicado 2020

Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models

por Trujillo‐Estrada, Laura, Nguyen, Cassidy, da Cunha, Celia, Cai, Lena, Forner, Stefania, Martini, Alessandra C., Ager, Rahasson R., Prieto, Gilberto Aleph, Cotman, Carl W., Baglietto‐Vargas, David, LaFerla, Frank M.
Publicado 2019

Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

por Wong, Daniel R., Magaki, Shino D., Vinters, Harry V., Yong, William H., Monuki, Edwin S., Williams, Christopher K., Martini, Alessandra C., DeCarli, Charles, Khacherian, Chris, Graff, John P., Dugger, Brittany N., Keiser, Michael J.
Publicado 2023

Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

por Wong, Daniel R., Magaki, Shino D., Vinters, Harry V., Yong, William H., Monuki, Edwin S., Williams, Christopher K., Martini, Alessandra C., DeCarli, Charles, Khacherian, Chris, Graff, John P., Dugger, Brittany N., Keiser, Michael J.
Publicado 2023

Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease

por Baglietto‐Vargas, David, Prieto, Gilberto Aleph, Limon, Agenor, Forner, Stefania, Rodriguez‐Ortiz, Carlos J., Ikemura, Kenji, Ager, Rahasson R., Medeiros, Rodrigo, Trujillo‐Estrada, Laura, Martini, Alessandra C., Kitazawa, Masashi, Davila, Jose C., Cotman, Carl W., Gutierrez, Antonia, LaFerla, Frank M.
Publicado 2018

SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer’s Disease

por Trujillo-Estrada, Laura, Vanderklish, Peter W., Nguyen, Marie Minh Thu, Kuang, Run Rong, Nguyen, Caroline, Huynh, Eric, da Cunha, Celia, Javonillo, Dominic Ibarra, Forner, Stefania, Martini, Alessandra C., Sarraf, Stella T., Simmon, Vincent F., Baglietto-Vargas, David, LaFerla, Frank M.
Publicado 2021

Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

por Shabestari, Sepideh Kiani, Morabito, Samuel, Danhash, Emma Pascal, McQuade, Amanda, Sanchez, Jessica Ramirez, Miyoshi, Emily, Chadarevian, Jean Paul, Claes, Christel, Coburn, Morgan Alexandra, Hasselmann, Jonathan, Hidalgo, Jorge, Tran, Kayla Nhi, Martini, Alessandra C., Rothermich, Winston Chang, Pascual, Jesse, Head, Elizabeth, Hume, David A., Pridans, Clare, Davtyan, Hayk, Swarup, Vivek, Blurton-Jones, Mathew
Publicado 2022

Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus

por Forner, Stefania, Martini, Alessandra C., Prieto, G. Aleph, Dang, Cindy T., Rodriguez-Ortiz, Carlos J., Reyes-Ruiz, Jorge Mauricio, Trujillo-Estrada, Laura, da Cunha, Celia, Andrews, Elizabeth J., Phan, Jimmy, Vu Ha, Jordan, Chang, Allissa V. Z. D., Levites, Yona, Cruz, Pedro E., Ager, Rahasson, Medeiros, Rodrigo, Kitazawa, Masashi, Glabe, Charles G., Cotman, Carl W., Golde, Todd, Baglietto-Vargas, David, LaFerla, Frank M.
Publicado 2019

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

por Baglietto-Vargas, David, Forner, Stefania, Cai, Lena, Martini, Alessandra C., Trujillo-Estrada, Laura, Swarup, Vivek, Nguyen, Marie Minh Thu, Do Huynh, Kelly, Javonillo, Dominic I., Tran, Kristine Minh, Phan, Jimmy, Jiang, Shan, Kramár, Enikö A., Nuñez-Diaz, Cristina, Balderrama-Gutierrez, Gabriela, Garcia, Franklin, Childs, Jessica, Rodriguez-Ortiz, Carlos J., Garcia-Leon, Juan Antonio, Kitazawa, Masashi, Shahnawaz, Mohammad, Matheos, Dina P., Ma, Xinyi, Da Cunha, Celia, Walls, Ken C., Ager, Rahasson R., Soto, Claudio, Gutierrez, Antonia, Moreno-Gonzalez, Ines, Mortazavi, Ali, Tenner, Andrea J., MacGregor, Grant R., Wood, Marcelo, Green, Kim N., LaFerla, Frank M.
Publicado 2021