Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

por Bočkaj, Irena, Martini, Tosca E. I., Smit, Marlinde J., Armandari, Inna, Bakker, Bjorn, Wardenaar, René, Meeuwsen-de Boer, Tiny G. J., Bakker, Petra L., Spierings, Diana C. J., Hoving, Eelco W., Guryev, Victor, Foijer, Floris, Bruggeman, Sophia W. M.
Publicado 2022

CREB signaling activity correlates with differentiation and survival in medulloblastoma

por Armandari, Inna, Zomerman, Walderik W., Plasschaert, Sabine L. A., Smit, Marlinde J., Martini, Tosca. E. I., de Camargo Magalhães, Eduardo S., Hogeling, Shanna M., Rozema-Huizinga, Geesina C., Lourens, Harm J., Meeuwsen-de Boer, Tiny G. J., Scherpen, Frank J. G., de Bont, Eveline S. J. M., Bruggeman, Sophia W. M.
Publicado 2021

The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity

por Smit, Marlinde J., Martini, Tosca E. I., Armandari, Inna, Bočkaj, Irena, Zomerman, Walderik W., de Camargo Magalhães, Eduardo S., Siragna, Zillah, Meeuwsen, Tiny G. J., Scherpen, Frank J. G., Schoots, Mirthe H., Ritsema, Martha, den Dunnen, Wilfred F. A., Hoving, Eelco W., Paridaen, Judith T. M. L., de Haan, Gerald, Guryev, Victor, Bruggeman, Sophia W. M.
Publicado 2022

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

por Bočkaj, Irena, Martini, Tosca E. I., de Camargo Magalhães, Eduardo S., Bakker, Petra L., Meeuwsen-de Boer, Tiny G. J., Armandari, Inna, Meuleman, Saskia L., Mondria, Marin T., Stok, Colin, Kok, Yannick P., Bakker, Bjorn, Wardenaar, René, Seiler, Jonas, Broekhuis, Mathilde J. C., van den Bos, Hilda, Spierings, Diana C. J., Ringnalda, Femke C. A., Clevers, Hans, Schüller, Ulrich, van Vugt, Marcel A. T. M., Foijer, Floris, Bruggeman, Sophia W. M.
Publicado 2021