Mitochondrial Stress Signalling: HTRA2 and Parkinson's Disease

por Desideri, Enrico, Martins, L. Miguel
Publicado 2012

Mitochondrial quality control and neurological disease: an emerging connection

por de Castro, Inês Pimenta, Martins, L. Miguel, Tufi, Roberta
Publicado 2010

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease

por Costa, A C, Loh, S H Y, Martins, L Miguel
Publicado 2013

Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress()

por Moisoi, Nicoleta, Fedele, Valentina, Edwards, Jennifer, Martins, L. Miguel
Publicado 2014

Enhancing NAD(+) salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease

por Lehmann, Susann, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2016

Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease

por Garrido-Maraver, Juan, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2020

Mitochondrial Quality Control and Parkinson’s Disease: A Pathway Unfolds

por de Castro, Inês Pimenta, Martins, L. Miguel, Loh, Samantha Hui Yong
Publicado 2010

Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease

por Yu, Yizhou, Fedele, Giorgio, Celardo, Ivana, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2021

Correction: Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease

por Yu, Yizhou, Fedele, Giorgio, Celardo, Ivana, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2021

Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea

por Plun-Favreau, Hélène, Lewis, Patrick A., Hardy, John, Martins, L. Miguel, Wood, Nicholas W.
Publicado 2010

Increased cysteine metabolism in PINK1 models of Parkinson's disease

por Travaglio, Marco, Michopoulos, Filippos, Yu, Yizhou, Popovic, Rebeka, Foster, Edmund, Coen, Muireann, Martins, L. Miguel
Publicado 2023

Upregulation of Tribbles decreases body weight and increases sleep duration

por Popovic, Rebeka, Yu, Yizhou, Leal, Nuno Santos, Fedele, Giorgio, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2023

Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways

por Popovic, Rebeka, Celardo, Ivana, Yu, Yizhou, Costa, Ana C., Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2021

Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice

por Gerhardt, Ellen, Gräber, Simone, Szegő, Éva M., Moisoi, Nicoleta, Martins, L. Miguel, Outeiro, Tiago F., Kermer, Pawel
Publicado 2011

Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin

por Garrido-Maraver, Juan, Celardo, Ivana, Costa, Ana C., Lehmann, Susann, Loh, Samantha H. Y., Martins, L. Miguel
Publicado 2019

Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster

por Scialò, Filippo, Sriram, Ashwin, Stefanatos, Rhoda, Spriggs, Ruth V., Loh, Samantha H.Y., Martins, L. Miguel, Sanz, Alberto
Publicado 2020

Early detection of pre-malignant lesions in a KRAS(G12D)-driven mouse lung cancer model by monitoring circulating free DNA

por Rakhit, Callum P., Trigg, Ricky M., Le Quesne, John, Kelly, Michael, Shaw, Jacqueline A., Pritchard, Catrin, Martins, L. Miguel
Publicado 2019

Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations

por Lynch, David S., Loh, Samantha H.Y., Harley, Jasmine, Noyce, Alastair J., Martins, L. Miguel, Wood, Nicholas W., Houlden, Henry, Plun-Favreau, Helene
Publicado 2017

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin

por Tain, Luke S., Chowdhury, Ruhena B., Tao, Ran N., Plun-Favreau, Helene, Moisoi, Nicoleta, Martins, L. Miguel, Downward, Julian, Whitworth, Alexander J., Tapon, Nicolas
Publicado 2009

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2

por Merski, Matthew, Moreira, Cátia, Abreu, Rui MV, Ramos, Maria João, Fernandes, Pedro A, Martins, L Miguel, Pereira, Pedro José Barbosa, Macedo-Ribeiro, Sandra
Publicado 2017