High Throughput Screening for Inhibitors of Alpha-Galactosidase

por Motabar, Omid, Liu, Ke, Southall, Noel, Marugan, Juan J, Goldin, Ehud, Sidransky, Ellen, Zheng, Wei
Publicado 2010

Anti-apoptotic and Matrix Remodeling Actions of a Small Molecule Agonist of the Human Relaxin Receptor, ML290 in Mice With Unilateral Ureteral Obstruction

por Ng, Hooi Hooi, Soula, Mariluz, Rivas, Bryan, Wilson, Kenneth J., Marugan, Juan J., Agoulnik, Alexander I.
Publicado 2021

Plasma and Tissue Concentrations of α-Tocopherol and δ-Tocopherol Following High Dose Dietary Supplementation in Mice

por Baxter, Laura L., Marugan, Juan J., Xiao, Jingbo, Incao, Art, McKew, John C., Zheng, Wei, Pavan, William J.
Publicado 2012

Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease

por Geng, Haifeng, Whiteley, Grace, Ribbens, Jameson, Zheng, Wei, Southall, Noel, Hu, Xin, Marugan, Juan J., Ferrer, Marc, Maegawa, Gustavo H. B.
Publicado 2011

In Silico Screening of Inhibitors of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease

por Hu, Xin, Morazzani, Elaine, Compton, Jaimee R., Harmon, Moeshia, Soloveva, Veronica, Glass, Pamela J., Garcia, Andres Dulcey, Marugan, Juan J., Legler, Patricia M.
Publicado 2023

A Homogenous Luminescence Assay Reveals Novel Inhibitors for Giardia Lamblia Carbamate Kinase

por Chen, Catherine Z, Southall, Noel, Galkin, Andrey, Lim, Kap, Marugan, Juan J, Kulakova, Liudmila, Shinn, Paul, van Leer, Danielle, Zheng, Wei, Herzberg, Osnat
Publicado 2012

Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses

por Sima, Ni, Li, Rong, Huang, Wei, Xu, Miao, Beers, Jeanette, Zou, Jizhong, Titus, Steven, Ottinger, Elizabeth A., Marugan, Juan J., Xie, Xing, Zheng, Wei
Publicado 2018

Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells

por Li, Rong, Hao, Jon, Fujiwara, Hideji, Xu, Miao, Yang, Shu, Dai, Sheng, Long, Yan, Swaroop, Manju, Li, Changhui, Vu, Mylinh, Marugan, Juan J., Ory, Daniel S., Zheng, Wei
Publicado 2017

Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A

por Long, Yan, Xu, Miao, Li, Rong, Dai, Sheng, Beers, Jeanette, Chen, Guokai, Soheilian, Ferri, Baxa, Ulrich, Wang, Mengqiao, Marugan, Juan J., Muro, Silvia, Li, Zhiyuan, Brady, Roscoe, Zheng, Wei
Publicado 2016

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

por He, Shanshan, Xiao, Jingbo, Dulcey, Andrés E., Lin, Billy, Rolt, Adam, Hu, Zongyi, Hu, Xin, Wang, Amy Q., Xu, Xin, Southall, Noel, Ferrer, Marc, Zheng, Wei, Liang, T. Jake, Marugan, Juan J.
Publicado 2015

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1

por Kocan, Martina, Sarwar, Mohsin, Ang, Sheng Y., Xiao, Jingbo, Marugan, Juan J., Hossain, Mohammed A., Wang, Chao, Hutchinson, Dana S., Samuel, Chrishan S., Agoulnik, Alexander I., Bathgate, Ross A. D., Summers, Roger J.
Publicado 2017

A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp

por Bhattacharyya, Nisan, Hu, Xin, Chen, Catherine Z., Mathews Griner, Lesley A., Zheng, Wei, Inglese, James, Austin, Christopher P., Marugan, Juan J., Southall, Noel, Neumann, Susanne, Northup, John K., Ferrer, Marc, Collins, Michael T.
Publicado 2014

Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290

por Huang, Zaohua, Myhr, Courtney, Bathgate, Ross A. D., Ho, Brian A., Bueno, Amaya, Hu, Xin, Xiao, Jingbo, Southall, Noel, Barnaeva, Elena, Agoulnik, Irina U., Marugan, Juan J., Ferrer, Marc, Agoulnik, Alexander I.
Publicado 2015

Teaching principles of translational science to a broad scientific audience using a case study approach: A pilot course from the National Center for Advancing Translational Science...

por Faupel-Badger, Jessica M., Vogel, Amanda L., Hussain, Shadab F., Austin, Christopher P., Hall, Matthew D., Ness, Elizabeth, Sanderson, Philip, Terse, Pramod S., Xu, Xin, Balakrishnan, Krishna, Patnaik, Samarjit, Marugan, Juan J., Rudloff, Udo, Ferrer, Marc
Publicado 2022

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

por Hoskins, Jason W., Ofori, Leslie O., Chen, Catherine Z., Kumar, Amit, Sobczak, Krzysztof, Nakamori, Masayuki, Southall, Noel, Patnaik, Samarjit, Marugan, Juan J., Zheng, Wei, Austin, Christopher P., Disney, Matthew D., Miller, Benjamin L., Thornton, Charles A.
Publicado 2014

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

por Mukhopadhyay, Rupkatha, Roy, Sujayita, Venkatadri, Rajkumar, Su, Yu-Pin, Ye, Wenjuan, Barnaeva, Elena, Mathews Griner, Lesley, Southall, Noel, Hu, Xin, Wang, Amy Q., Xu, Xin, Dulcey, Andrés E., Marugan, Juan J., Ferrer, Marc, Arav-Boger, Ravit
Publicado 2016

Identification of Small Molecule Enhancers of Immunotherapy for Melanoma

por Dextras, Christopher, Dashnyam, Myagmarjav, Griner, Lesley A. Mathews, Sundaresan, Janani, Chim, Bryan, Yu, Zhiya, Vodnala, Suman, Lee, Chyi-Chia Richard, Hu, Xin, Southall, Noel, Marugan, Juan J., Jadhav, Ajit, Restifo, Nicholas P., Acquavella, Nicolas, Ferrer, Marc, Singh, Anju
Publicado 2020

Discovery, Optimization, and Characterization of Novel D(2) Dopamine Receptor Selective Antagonists

por Xiao, Jingbo, Free, R. Benjamin, Barnaeva, Elena, Conroy, Jennie L., Doyle, Trevor, Miller, Brittney, Bryant-Genevier, Marthe, Taylor, Mercedes K., Hu, Xin, Dulcey, Andrés E., Southall, Noel, Ferrer, Marc, Titus, Steve, Zheng, Wei, Sibley, David R., Marugan, Juan J.
Publicado 2014

c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer’s disease

por León, Rilda, Gutiérrez, Daniela A., Pinto, Claudio, Morales, Cristian, de la Fuente, Catalina, Riquelme, Cristóbal, Cortés, Bastián I., González-Martin, Adrián, Chamorro, David, Espinosa, Nelson, Fuentealba, Pablo, Cancino, Gonzalo I., Zanlungo, Silvana, Dulcey, Andrés E., Marugan, Juan J., Álvarez Rojas, Alejandra
Publicado 2023

A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase

por Martinez, Natalia J., Asawa, Rosita R., Cyr, Matthew G., Zakharov, Alexey, Urban, Daniel J., Roth, Jacob S., Wallgren, Eric, Klumpp-Thomas, Carleen, Coussens, Nathan P., Rai, Ganesha, Yang, Shyh-Ming, Hall, Matthew D., Marugan, Juan J., Simeonov, Anton, Henderson, Mark J.
Publicado 2018