Towards Increasing the Clinical Relevance of In Silico Methods to Predict Pathogenic Missense Variants

por Masica, David L., Karchin, Rachel
Publicado 2016

Network Analysis of Protein Adaptation: Modeling the Functional Impact of Multiple Mutations

por Beleva Guthrie, Violeta, Masica, David L, Fraser, Andrew, Federico, Joseph, Fan, Yunfan, Camps, Manel, Karchin, Rachel
Publicado 2018

Fast, accurate, and racially unbiased pan-cancer tumor-only variant calling with tabular machine learning

por McLaughlin, R. Tyler, Asthana, Maansi, Di Meo, Marc, Ceccarelli, Michele, Jacob, Howard J., Masica, David L.
Publicado 2023

Assessing the Pathogenicity of Insertion and Deletion Variants with the Variant Effect Scoring Tool (VEST‐Indel)

por Douville, Christopher, Masica, David L., Stenson, Peter D., Cooper, David N., Gygax, Derek M., Kim, Rick, Ryan, Michael, Karchin, Rachel
Publicado 2015

Autologous reconstitution of human cancer and immune system in vivo

por Fu, Juan, Sen, Rupashree, Masica, David L., Karchin, Rachel, Pardoll, Drew, Walter, Vonn, Hayes, D. Neil, Chung, Christine H., Kim, Young J.
Publicado 2016

Association of Baseline and Pharmacodynamic Biomarkers With Outcomes in Patients Treated With the PD-1 Inhibitor Budigalimab

por Lambert, Stacie L., Zhang, Chun, Guo, Claire, Turan, Tolga, Masica, David L., Englert, Stefan, Fang, Yuni, Sheridan, James, McLaughlin, Robert Tyler, Tribouley, Catherine, Vosganian, Greg, Afar, Daniel
Publicado 2022

Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene

por Sosnay, Patrick R, Siklosi, Karen R, Van Goor, Fredrick, Kaniecki, Kyle, Yu, Haihui, Sharma, Neeraj, Ramalho, Anabela S, Amaral, Margarida D, Dorfman, Ruslan, Zielenski, Julian, Masica, David L, Karchin, Rachel, Millen, Linda, Thomas, Philip J, Patrinos, George P, Corey, Mary, Lewis, Michelle H, Rommens, Johanna M, Castellani, Carlo, Penland, Christopher M, Cutting, Garry R
Publicado 2013

Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework

por Glusman, Gustavo, Rose, Peter W., Prlić, Andreas, Dougherty, Jennifer, Duarte, José M., Hoffman, Andrew S., Barton, Geoffrey J., Bendixen, Emøke, Bergquist, Timothy, Bock, Christian, Brunk, Elizabeth, Buljan, Marija, Burley, Stephen K., Cai, Binghuang, Carter, Hannah, Gao, JianJiong, Godzik, Adam, Heuer, Michael, Hicks, Michael, Hrabe, Thomas, Karchin, Rachel, Leman, Julia Koehler, Lane, Lydie, Masica, David L., Mooney, Sean D., Moult, John, Omenn, Gilbert S., Pearl, Frances, Pejaver, Vikas, Reynolds, Sheila M., Rokem, Ariel, Schwede, Torsten, Song, Sicheng, Tilgner, Hagen, Valasatava, Yana, Zhang, Yang, Deutsch, Eric W.
Publicado 2017