Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against chall...

por Liu, Ye V., Massare, Michael J., Barnard, Dale L., Kort, Thomas, Nathan, Margret, Wang, Lei, Smith, Gale
Publicado 2011

Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA

por Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Zhou, Haixia, Tian, Jing-Hui, Zhou, Bin, Shinde, Vivek, Glenn, Gregory M., Smith, Gale
Publicado 2020

An insect cell derived respiratory syncytial virus (RSV) F nanoparticle vaccine induces antigenic site II antibodies and protects against RSV challenge in cotton rats by active and...

por Raghunandan, Rama, Lu, Hanxin, Zhou, Bin, Xabier, Mimi Guebre, Massare, Michael J., Flyer, David C., Fries, Louis F., Smith, Gale E., Glenn, Gregory M.
Publicado 2014

Severe Acute Respiratory Syndrome Coronavirus 2 Receptor (Human Angiotensin-Converting Enzyme 2) Binding Inhibition Assay: A Rapid, High-Throughput Assay Useful for Vaccine Immunog...

por Plested, Joyce S., Zhu, Mingzhu, Cloney-Clark, Shane, Massuda, Edmond, Patel, Urvashi, Klindworth, Andrew, Massare, Michael J., Cai, Rongman, Fries, Louis, Glenn, Greg, Kalkeri, Raj
Publicado 2023

Flexible RSV Prefusogenic Fusion Glycoprotein Exposes Multiple Neutralizing Epitopes that May Collectively Contribute to Protective Immunity

por Patel, Nita, Tian, Jing-Hui, Flores, Rhonda, Jacobson, Kelsey, Walker, Michelle, Portnoff, Alyse, Gueber-Xabier, Mimi, Massare, Michael J., Glenn, Greg, Ellingsworth, Larry, Smith, Gale
Publicado 2020

Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein

por Xie, Qingqing, Wang, Zhao, Ni, Fengyun, Chen, Xiaorui, Ma, Jianpeng, Patel, Nita, Lu, Hanxin, Liu, Ye, Tian, Jing-Hui, Flyer, David, Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Wang, Qinghua
Publicado 2019

NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

por Guebre-Xabier, Mimi, Patel, Nita, Tian, Jing-Hui, Zhou, Bin, Maciejewski, Sonia, Lam, Kristal, Portnoff, Alyse D., Massare, Michael J., Frieman, Matthew B., Piedra, Pedro A., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Publicado 2020

Induction of Cross-Reactive Hemagglutination Inhibiting Antibody and Polyfunctional CD4+ T-Cell Responses by a Recombinant Matrix-M–Adjuvanted Hemagglutinin Nanoparticle Influenza...

por Shinde, Vivek, Cai, Rongman, Plested, Joyce, Cho, Iksung, Fiske, Jamie, Pham, Xuan, Zhu, Mingzhu, Cloney-Clark, Shane, Wang, Nan, Zhou, Haixia, Zhou, Bin, Patel, Nita, Massare, Michael J, Fix, Amy, Spindler, Michelle, Thomas, David Nigel, Smith, Gale, Fries, Louis, Glenn, Gregory M
Publicado 2020

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

por Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
Publicado 2020

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

por Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
Publicado 2020

Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants

por Logue, James, Johnson, Robert M., Patel, Nita, Zhou, Bin, Maciejewski, Sonia, Foreman, Bryant, Zhou, Haixia, Portnoff, Alyse D., Tian, Jing-Hui, Rehman, Asma, McGrath, Marisa E., Haupt, Robert E., Weston, Stuart M., Baracco, Lauren, Hammond, Holly, Guebre-Xabier, Mimi, Dillen, Carly, Madhangi, M., Greene, Ann M., Massare, Michael J., Glenn, Greg M., Smith, Gale, Frieman, Matthew B.
Publicado 2023

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice

por Tian, Jing-Hui, Patel, Nita, Haupt, Robert, Zhou, Haixia, Weston, Stuart, Hammond, Holly, Logue, James, Portnoff, Alyse D., Norton, James, Guebre-Xabier, Mimi, Zhou, Bin, Jacobson, Kelsey, Maciejewski, Sonia, Khatoon, Rafia, Wisniewska, Malgorzata, Moffitt, Will, Kluepfel-Stahl, Stefanie, Ekechukwu, Betty, Papin, James, Boddapati, Sarathi, Jason Wong, C., Piedra, Pedro A., Frieman, Matthew B., Massare, Michael J., Fries, Louis, Bengtsson, Karin Lövgren, Stertman, Linda, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Publicado 2021

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M(™) vaccination

por Gorman, Matthew J, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yaun, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Publicado 2021

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

por Gorman, Matthew J., Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex L., Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn A., Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas A., Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Publicado 2021