Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions

por Massari, Serena, Desantis, Jenny, Nizi, Maria Giulia, Cecchetti, Violetta, Tabarrini, Oriana
Publicado 2020

Q-raKtion: A Semiautomated KNIME Workflow for Bioactivity Data Points Curation

por Palazzotti, Deborah, Fiorelli, Martina, Sabatini, Stefano, Massari, Serena, Barreca, Maria Letizia, Astolfi, Andrea
Publicado 2022

Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy

por Pismataro, Maria Chiara, Astolfi, Andrea, Barreca, Maria Letizia, Pacetti, Martina, Schenone, Silvia, Bandiera, Tiziano, Carbone, Anna, Massari, Serena
Publicado 2023

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

por Desantis, Jenny, Massari, Serena, Corona, Angela, Astolfi, Andrea, Sabatini, Stefano, Manfroni, Giuseppe, Palazzotti, Deborah, Cecchetti, Violetta, Pannecouque, Christophe, Tramontano, Enzo, Tabarrini, Oriana
Publicado 2020

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

por Massari, Serena, Corona, Angela, Distinto, Simona, Desantis, Jenny, Caredda, Alessia, Sabatini, Stefano, Manfroni, Giuseppe, Felicetti, Tommaso, Cecchetti, Violetta, Pannecouque, Christophe, Maccioni, Elias, Tramontano, Enzo, Tabarrini, Oriana
Publicado 2018

From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemi...

por Astolfi, Andrea, Milano, Francesca, Palazzotti, Deborah, Brea, Jose, Pismataro, Maria Chiara, Morlando, Mariangela, Tabarrini, Oriana, Loza, Maria Isabel, Massari, Serena, Martelli, Maria Paola, Barreca, Maria Letizia
Publicado 2022

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

por Felicetti, Tommaso, Mangiaterra, Gianmarco, Cannalire, Rolando, Cedraro, Nicholas, Pietrella, Donatella, Astolfi, Andrea, Massari, Serena, Tabarrini, Oriana, Manfroni, Giuseppe, Barreca, Maria Letizia, Cecchetti, Violetta, Biavasco, Francesca, Sabatini, Stefano
Publicado 2020

Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors

por Cannalire, Rolando, Mangiaterra, Gianmarco, Felicetti, Tommaso, Astolfi, Andrea, Cedraro, Nicholas, Massari, Serena, Manfroni, Giuseppe, Tabarrini, Oriana, Vaiasicca, Salvatore, Barreca, Maria Letizia, Cecchetti, Violetta, Biavasco, Francesca, Sabatini, Stefano
Publicado 2020

2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors

por Nkizinkiko, Yves, Desantis, Jenny, Koivunen, Jarkko, Haikarainen, Teemu, Murthy, Sudarshan, Sancineto, Luca, Massari, Serena, Ianni, Federica, Obaji, Ezeogo, Loza, Maria I., Pihlajaniemi, Taina, Brea, Jose, Tabarrini, Oriana, Lehtiö, Lari
Publicado 2018

From Quinoline to Quinazoline‐Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search

por Cedraro, Nicholas, Cannalire, Rolando, Astolfi, Andrea, Mangiaterra, Gianmarco, Felicetti, Tommaso, Vaiasicca, Salvatore, Cernicchi, Giada, Massari, Serena, Manfroni, Giuseppe, Tabarrini, Oriana, Cecchetti, Violetta, Barreca, Maria Letizia, Biavasco, Francesca, Sabatini, Stefano
Publicado 2021

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

por Massari, Serena, Bertagnin, Chiara, Pismataro, Maria Chiara, Donnadio, Anna, Nannetti, Giulio, Felicetti, Tommaso, Di Bona, Stefano, Nizi, Maria Giulia, Tensi, Leonardo, Manfroni, Giuseppe, Loza, Maria Isabel, Sabatini, Stefano, Cecchetti, Violetta, Brea, Jose, Goracci, Laura, Loregian, Arianna, Tabarrini, Oriana
Publicado 2021

[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

por Murthy, Sudarshan, Nizi, Maria Giulia, Maksimainen, Mirko M., Massari, Serena, Alaviuhkola, Juho, Lippok, Barbara E., Vagaggini, Chiara, Sowa, Sven T., Galera-Prat, Albert, Ashok, Yashwanth, Venkannagari, Harikanth, Prunskaite-Hyyryläinen, Renata, Dreassi, Elena, Lüscher, Bernhard, Korn, Patricia, Tabarrini, Oriana, Lehtiö, Lari
Publicado 2023

Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity

por Nizi, Maria Giulia, Persoons, Leentje, Corona, Angela, Felicetti, Tommaso, Cernicchi, Giada, Massari, Serena, Manfroni, Giuseppe, Vangeel, Laura, Barreca, Maria Letizia, Esposito, Francesca, Jochmans, Dirk, Milia, Jessica, Cecchetti, Violetta, Schols, Dominique, Neyts, Johan, Tramontano, Enzo, Sabatini, Stefano, De Jonghe, Steven, Tabarrini, Oriana
Publicado 2022

Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

por Gargaro, Marco, Vacca, Carmine, Massari, Serena, Scalisi, Giulia, Manni, Giorgia, Mondanelli, Giada, Mazza, Emilia M. C., Bicciato, Silvio, Pallotta, Maria T., Orabona, Ciriana, Belladonna, Maria L., Volpi, Claudia, Bianchi, Roberta, Matino, Davide, Iacono, Alberta, Panfili, Eleonora, Proietti, Elisa, Iamandii, Ioana Maria, Cecchetti, Violetta, Puccetti, Paolo, Tabarrini, Oriana, Fallarino, Francesca, Grohmann, Ursula
Publicado 2019