MicroRNAs that interfere with RNAi

por Massirer, Katlin B., Pasquinelli, Amy E.
Publicado 2013

The miR-35-41 Family of MicroRNAs Regulates RNAi Sensitivity in Caenorhabditis elegans

por Massirer, Katlin B., Perez, Saida G., Mondol, Vanessa, Pasquinelli, Amy E.
Publicado 2012

Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding

por Aquino, Bruno, da Silva, Viviane C. H., Massirer, Katlin B., Arruda, Paulo
Publicado 2020

Structural Characterization of Maize SIRK1 Kinase Domain Reveals an Unusual Architecture of the Activation Segment

por Aquino, Bruno, Couñago, Rafael M., Verza, Natalia, Ferreira, Lucas M., Massirer, Katlin B., Gileadi, Opher, Arruda, Paulo
Publicado 2017

LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in C. elegans

por Van Wynsberghe, Priscilla M., Kai, Zoya S., Massirer, Katlin B., Burton, Victoria H., Yeo, Gene W., Pasquinelli, Amy E.
Publicado 2011

A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells

por Cunha, Micael R., Catta-Preta, Carolina M.C., Takarada, Jéssica E., Moreira, Gabriela A., Massirer, Katlin B., Couñago, Rafael M.
Publicado 2023

Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer

por Scott, Fiona, Fala, Angela M., Pennicott, Lewis E., Reuillon, Tristan D., Massirer, Katlin B., Elkins, Jonathan M., Ward, Simon E.
Publicado 2020

Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors

por Santiago, André da Silva, Couñago, Rafael M., Ramos, Priscila Zonzini, Godoi, Paulo H. C., Massirer, Katlin B., Gileadi, Opher, Elkins, Jonathan M.
Publicado 2018

The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity

por Righetto, Germanna Lima, Sriranganadane, Dev, Halabelian, Levon, Chiodi, Carla G., Elkins, Jonathan M., Massirer, Katlin B., Gileadi, Opher, Menossi, Marcelo, Couñago, Rafael M.
Publicado 2019

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans

por De-Souza, Evandro A, Camara, Henrique, Salgueiro, Willian G, Moro, Raíssa P, Knittel, Thiago L, Tonon, Guilherme, Pinto, Silas, Pinca, Ana Paula F, Antebi, Adam, Pasquinelli, Amy E, Massirer, Katlin B, Mori, Marcelo A
Publicado 2019

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

por Couñago, Rafael M., Allerston, Charles K., Savitsky, Pavel, Azevedo, Hatylas, Godoi, Paulo H., Wells, Carrow I., Mascarello, Alessandra, de Souza Gama, Fernando H., Massirer, Katlin B., Zuercher, William J., Guimarães, Cristiano R. W., Gileadi, Opher
Publicado 2017

UHMK1 is a novel splicing regulatory kinase

por Arfelli, Vanessa C., Chang, Yun-Chien, Bagnoli, Johannes W., Kerbs, Paul, Ciamponi, Felipe E., Paz, Laissa M. da S., Pankivskyi, Serhii, de Matha Salone, Jean, Maucuer, Alexandre, Massirer, Katlin B., Enard, Wolfgang, Kuster, Bernhard, Greif, Philipp A., Archangelo, Leticia Fröhlich
Publicado 2023

Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis

por Pinto, Silas, Sato, Vitor N., De-Souza, Evandro A., Ferraz, Rafael C., Camara, Henrique, Pinca, Ana Paula F., Mazzotti, Diego R., Lovci, Michael T., Tonon, Guilherme, Lopes-Ramos, Camila M., Parmigiani, Raphael B., Wurtele, Martin, Massirer, Katlin B., Mori, Marcelo A.
Publicado 2018

Binding and structural analyses of potent inhibitors of the human Ca(2+)/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-availabl...

por Profeta, Gerson S., dos Reis, Caio V., Santiago, André da S., Godoi, Paulo H. C., Fala, Angela M., Wells, Carrow I., Sartori, Roger, Salmazo, Anita P. T., Ramos, Priscila Z., Massirer, Katlin B., Elkins, Jonathan M., Drewry, David H., Gileadi, Opher, Couñago, Rafael M.
Publicado 2019

Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2

por Serafim, Ricardo A. M., de Souza Gama, Fernando H., Dutra, Luiz A., dos Reis, Caio V., Vasconcelos, Stanley N. S., da Silva Santiago, André, Takarada, Jéssica E., Di Pillo, Fúlvia, Azevedo, Hatylas, Mascarello, Alessandra, Elkins, Jonathan M., Massirer, Katlin B., Gileadi, Opher, Guimarães, Cristiano R. W., Couñago, Rafael M.
Publicado 2019

PRMT inhibition induces a viral mimicry response in triple-negative breast cancer

por Wu, Qin, Nie, David Y., Ba-alawi, Wail, Ji, YiShuai, Zhang, ZiWen, Cruickshank, Jennifer, Haight, Jillian, Ciamponi, Felipe E., Chen, Jocelyn, Duan, Shili, Shen, Yudao, Liu, Jing, Marhon, Sajid A., Mehdipour, Parinaz, Szewczyk, Magdalena M., Dogan-Artun, Nergiz, Chen, WenJun, Zhang, Lan Xin, Deblois, Genevieve, Prinos, Panagiotis, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Jin, Jian, De Carvalho, Daniel D., Haibe-Kains, Benjamin, Wang, XiaoJia, Cescon, David W., Lupien, Mathieu, Arrowsmith, Cheryl H.
Publicado 2022

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

por Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.
Publicado 2021