Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies

por Vauleon, Stephanie, Schutz, Katharina, Massonnet, Benoit, Gruben, Nanda, Manchester, Marianne, Buehler, Alessandra, Schick, Eginhard, Boak, Lauren, Hawellek, David J.
Publicado 2023

Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma

por Yamamoto, Yumi, Sanwald Ducray, Patricia, Björnsson, Marcus, Smart, Kevin, Grimsey, Paul, Vatakuti, Suresh, Portron, Agnes, Massonnet, Benoit, Norris, Daniel A., Silber Baumann, Hanna E.
Publicado 2023