Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

por DeVilbiss, Andrew W, Zhao, Zhiyu, Martin-Sandoval, Misty S, Ubellacker, Jessalyn M, Tasdogan, Alpaslan, Agathocleous, Michalis, Mathews, Thomas P, Morrison, Sean J
Publicado 2021

Phospholipase D1 Couples CD4(+) T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 Replication

por Taylor, Harry E., Simmons, Glenn E., Mathews, Thomas P., Khatua, Atanu K., Popik, Waldemar, Lindsley, Craig W., D’Aquila, Richard T., Brown, H. Alex
Publicado 2015

The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice

por Makarewich, Catherine A., Munir, Amir Z., Bezprozvannaya, Svetlana, Gibson, Aaron M., Young Kim, Soo, Martin-Sandoval, Misty S., Mathews, Thomas P., Szweda, Luke I., Bassel-Duby, Rhonda, Olson, Eric N.
Publicado 2022

Lymph protects metastasizing melanoma cells from ferroptosis

por Ubellacker, Jessalyn M., Tasdogan, Alpaslan, Ramesh, Vijayashree, Shen, Bo, Mitchell, Evann C., Martin-Sandoval, Misty S., Gu, Zhimin, McCormick, Michael L., Durham, Alison B., Spitz, Douglas R., Zhao, Zhiyu, Mathews, Thomas P., Morrison, Sean J.
Publicado 2020

BMAL1 drives muscle repair through control of hypoxic NAD(+) regeneration in satellite cells

por Zhu, Pei, Hamlish, Noah X., Thakkar, Abhishek Vijay, Steffeck, Adam W.T., Rendleman, Emily J., Khan, Nabiha H., Waldeck, Nathan J., DeVilbiss, Andrew W., Martin-Sandoval, Misty S., Mathews, Thomas P., Chandel, Navdeep S., Peek, Clara B.
Publicado 2022

Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells

por Aurora, Arin B., Khivansara, Vishal, Leach, Ashley, Gill, Jennifer G., Martin-Sandoval, Misty, Yang, Chendong, Kasitinon, Stacy Y., Bezwada, Divya, Tasdogan, Alpaslan, Gu, Wen, Mathews, Thomas P., Zhao, Zhiyu, DeBerardinis, Ralph J., Morrison, Sean J.
Publicado 2022

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

por Luengo, Alba, Abbott, Keene L., Davidson, Shawn M., Hosios, Aaron M., Faubert, Brandon, Chan, Sze Ham, Freinkman, Elizaveta, Zacharias, Lauren G., Mathews, Thomas P., Clish, Clary B., DeBerardinis, Ralph J., Lewis, Caroline A., Vander Heiden, Matthew G.
Publicado 2019

Metabolic heterogeneity confers differences in melanoma metastatic potential

por Tasdogan, Alpaslan, Faubert, Brandon, Ramesh, Vijayashree, Ubellacker, Jessalyn M., Shen, Bo, Solmonson, Ashley, Murphy, Malea M., Gu, Zhimin, Gu, Wen, Martin, Misty, Kasitinon, Stacy Y., Vandergriff, Travis, Mathews, Thomas P., Zhao, Zhiyu, Schadendorf, Dirk, DeBerardinis, Ralph J., Morrison, Sean J.
Publicado 2019

Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

por Soflaee, Mona Hoseini, Kesavan, Rushendhiran, Sahu, Umakant, Tasdogan, Alpaslan, Villa, Elodie, Djabari, Zied, Cai, Feng, Tran, Diem H., Vu, Hieu S., Ali, Eunus S., Rion, Halie, O’Hara, Brendan P., Kelekar, Sherwin, Hallett, James Hughes, Martin, Misty, Mathews, Thomas P., Gao, Peng, Asara, John M., Manning, Brendan D., Ben-Sahra, Issam, Hoxhaj, Gerta
Publicado 2022

Compartmentalized metabolism supports midgestation mammalian development

por Solmonson, Ashley, Faubert, Brandon, Gu, Wen, Rao, Aparna, Cowdin, Mitzy A., Menendez-Montes, Ivan, Kelekar, Sherwin, Rogers, Thomas J., Pan, Chunxiao, Guevara, Gerardo, Tarangelo, Amy, Zacharias, Lauren G., Martin-Sandoval, Misty S., Do, Duyen, Pachnis, Panayotis, Dumesnil, Dennis, Mathews, Thomas P., Tasdogan, Alpaslan, Pham, An, Cai, Ling, Zhao, Zhiyu, Ni, Min, Cleaver, Ondine, Sadek, Hesham A., Morrison, Sean J., DeBerardinis, Ralph J.
Publicado 2022

In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors

por Pachnis, Panayotis, Wu, Zheng, Faubert, Brandon, Tasdogan, Alpaslan, Gu, Wen, Shelton, Spencer, Solmonson, Ashley, Rao, Aparna D., Kaushik, Akash K., Rogers, Thomas J., Ubellacker, Jessalyn M., LaVigne, Collette A., Yang, Chendong, Ko, Bookyung, Ramesh, Vijayashree, Sudderth, Jessica, Zacharias, Lauren G., Martin-Sandoval, Misty S., Do, Duyen, Mathews, Thomas P., Zhao, Zhiyu, Mishra, Prashant, Morrison, Sean J., DeBerardinis, Ralph J.
Publicado 2022

In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

por Kaushik, Akash K., Tarangelo, Amy, Boroughs, Lindsey K., Ragavan, Mukundan, Zhang, Yuanyuan, Wu, Cheng-Yang, Li, Xiangyi, Ahumada, Kristen, Chiang, Jui-Chung, Tcheuyap, Vanina T., Saatchi, Faeze, Do, Quyen N., Yong, Cissy, Rosales, Tracy, Stevens, Christina, Rao, Aparna D., Faubert, Brandon, Pachnis, Panayotis, Zacharias, Lauren G., Vu, Hieu, Cai, Feng, Mathews, Thomas P., Genovese, Giannicola, Slusher, Barbara S., Kapur, Payal, Sun, Xiankai, Merritt, Matthew, Brugarolas, James, DeBerardinis, Ralph J.
Publicado 2022

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

por Shi, Diana D., Savani, Milan R., Levitt, Michael M., Wang, Adam C., Endress, Jennifer E., Bird, Cylaina E., Buehler, Joseph, Stopka, Sylwia A., Regan, Michael S., Lin, Yu-Fen, Puliyappadamba, Vinesh T., Gao, Wenhua, Khanal, Januka, Evans, Laura, Lee, Joyce H., Guo, Lei, Xiao, Yi, Xu, Min, Huang, Bofu, Jennings, Rebecca B., Bonal, Dennis M., Martin-Sandoval, Misty S., Dang, Tammie, Gattie, Lauren C., Cameron, Amy B., Lee, Sungwoo, Asara, John M., Kornblum, Harley I., Mak, Tak W., Looper, Ryan E., Nguyen, Quang-De, Signoretti, Sabina, Gradl, Stefan, Sutter, Andreas, Jeffers, Michael, Janzer, Andreas, Lehrman, Mark A., Zacharias, Lauren G., Mathews, Thomas P., Losman, Julie-Aurore, Richardson, Timothy E., Cahill, Daniel P., DeBerardinis, Ralph J., Ligon, Keith L., Xu, Lin, Ly, Peter, Agar, Nathalie Y.R., Abdullah, Kalil G., Harris, Isaac S., Kaelin, William G., McBrayer, Samuel K.
Publicado 2022