Adoption of Machine Learning in Pharmacometrics: An Overview of Recent Implementations and Their Considerations

por Janssen, Alexander, Bennis, Frank C., Mathôt, Ron A. A.
Publicado 2022

Short-Term Fasting Alters Pharmacokinetics of Cytochrome P450 Probe Drugs: Does Protein Binding Play a Role?

por Lammers, Laureen A., Achterbergh, Roos, Romijn, Johannes A., Mathôt, Ron A. A.
Publicado 2017

Nutritional Status Differentially Alters Cytochrome P450 3A4 (CYP3A4) and Uridine 5′-Diphospho-Glucuronosyltransferase (UGT) Mediated Drug Metabolism: Effect of Short-Term Fasting...

por Lammers, Laureen A., Achterbergh, Roos, Romijn, Johannes A., Mathôt, Ron A. A.
Publicado 2018

Target site antibiotic concentrations in orthopedic/trauma extremity surgery: is prophylactic cefazolin adequately dosed? A systematic review and meta-analysis

por Sanders, Fay R K, Goslings, J Carel, Mathôt, Ron A A, Schepers, Tim
Publicado 2019

Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis

por Bukkems, Laura H., Jönsson, Siv, Cnossen, Marjon H., Karlsson, Mats O., Mathôt, Ron A. A.
Publicado 2023

Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis

por Berends, Sophie E., Strik, Anne S., Löwenberg, Mark, D’Haens, Geert R., Mathôt, Ron A. A.
Publicado 2018

Medication use during end-of-life care in a palliative care centre

por Masman, Anniek D., van Dijk, Monique, Tibboel, Dick, Baar, Frans P. M., Mathôt, Ron A. A.
Publicado 2015

Population pharmacokinetics of subcutaneous infliximab CT‐P13 in Crohn’s disease and ulcerative colitis

por Hanzel, Jurij, Bukkems, Laura H., Gecse, Krisztina B., D’Haens, Geert R., Mathôt, Ron A. A.
Publicado 2021

Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach

por Lammers, Laureen A., Achterbergh, Roos, van Schaik, Ron H. N., Romijn, Johannes A., Mathôt, Ron A. A.
Publicado 2017

Limited sampling strategies for individualized BAX 855 prophylaxis in severe hemophilia A: in silico evaluation

por Bukkems, Laura H., Goedhart, Tine M.H.J., Zwaan, C. Michel, Cnossen, Marjon H., Mathôt, Ron A.A.
Publicado 2023

Inadequate vancomycin therapy in term and preterm neonates: a retrospective analysis of trough serum concentrations in relation to minimal inhibitory concentrations

por Sinkeler, Fleur S, de Haan, Timo R, Hodiamont, Caspar J, Bijleveld, Yuma A, Pajkrt, Dasja, Mathôt, Ron A A
Publicado 2014

Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab

por Schokker, Sandor, Fusetti, Fabrizia, Bonardi, Francesco, Molenaar, Remco J., Mathôt, Ron A.A., van Laarhoven, Hanneke W.M.
Publicado 2020

Transcapillary escape rate of (125)I-albumin in relation to timing of blood sampling: the need for standardization

por Chahid, Youssef, Rorije, Nienke M. G., el Boujoufi, Soufian, Mathôt, Ron A. A., Vogt, Liffert, Verberne, Hein J.
Publicado 2021

Population pharmacokinetic modeling of factor concentrates in hemophilia: an overview and evaluation of best practice

por Goedhart, Tine M. H. J., Bukkems, Laura H., Zwaan, C. Michel, Mathôt, Ron A. A., Cnossen, Marjon H.
Publicado 2021

Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study

por Bos, Jeannet C., Mistício, Mabor C., Nunguiane, Ginto, Mathôt, Ron A. A., van Hest, Reinier M., Prins, Jan M.
Publicado 2017

Association between Sports Participation, Factor VIII Levels and Bleeding in Hemophilia A

por Bukkems, Laura H., Versloot, Olav, Cnossen, Marjon H., Jönsson, Siv, Karlsson, Mats O., Mathôt, Ron A.A., Fischer, Kathelijn
Publicado 2022

Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients

por de Winter, Brenda C. M., van Gelder, Teun, Sombogaard, Ferdi, Shaw, Leslie M., van Hest, Reinier M., Mathot, Ron A. A.
Publicado 2009

A phase Ib study of everolimus combined with metformin for patients with advanced cancer

por Molenaar, Remco J., van de Venne, Tim, Weterman, Mariëtte J., Mathot, Ron A., Klümpen, Heinz-Josef, Richel, Dick J., Wilmink, Johanna W.
Publicado 2017

Dried blood samples can support monitoring of infliximab concentrations in patients with inflammatory bowel disease: A clinical validation

por Berends, Sophie E., D'Haens, Geert R. A. M., Schaap, Tiny, de Vries, Annick, Rispens, Theo, Bloem, Karien, Mathôt, Ron A. A.
Publicado 2019

Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative Infections: An Updated Review

por Hodiamont, Caspar J., van den Broek, Annemieke K., de Vroom, Suzanne L., Prins, Jan M., Mathôt, Ron A. A., van Hest, Reinier M.
Publicado 2022