Effects of intravenous oxycodone alone or in combination with naltrexone on measures of respiratory depression: a randomized placebo-controlled study

por Bass, Almasa, Webster, Lynn R., Matschke, Kyle T., Malhotra, Bimal K., Wolfram, Gernot
Publicado 2019

Evaluation of Proton Pump Inhibitor Esomeprazole on Crizotinib Pharmacokinetics in Healthy Participants

por Xu, Huiping, O'Gorman, Melissa, Matschke, Kyle, Boutros, Tanya, Brega, Nicoletta, Tan, Weiwei, Bello, Akintunde
Publicado 2021

Bioequivalence of Metformin in Ertugliflozin/Metformin Fixed‐Dose Combination Tablets to Canadian‐Sourced Metformin Coadministered With Ertugliflozin Under Fasted and Fed States...

por Dawra, Vikas Kumar, Pelletier, Kathleen, Matschke, Kyle, Shi, Haihong, Hickman, Anne, Zhou, Susan, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicado 2020

The Effect of a High-Fat Breakfast on the Pharmacokinetics of Moxidectin in Healthy Male Subjects: A Randomized Phase I Trial

por Korth-Bradley, Joan M., Parks, Virginia, Chalon, Stephan, Gourley, Ian, Matschke, Kyle, Cailleux, Karine, Fitoussi, Serge, Fleckenstein, Lawrence
Publicado 2012

Pharmacokinetic Properties of Single and Multiple Doses of Ertugliflozin, a Selective Inhibitor of SGLT2, in Healthy Chinese Subjects

por Li, Yinhua, Mu, Yuting, Shi, Haihong, Liang, Yali, Liu, Zeyuan, Matschke, Kyle, Hickman, Anne, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicado 2019

Relative bioavailability of ertugliflozin tablets containing the amorphous form versus tablets containing the cocrystal form

por Sahasrabudhe, Vaishali, Matschke, Kyle, Shi, Haihong, Hickman, Anne, Kong, Angela, Rodríguez Spong, Barbara, Nickerson, Beverly, Arora, Kapildev K.
Publicado 2022

Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recrea...

por Setnik, Beatrice, Bass, Almasa, Bramson, Candace, Levy-Cooperman, Naama, Malhotra, Bimal, Matschke, Kyle, Geoffroy, Pierre, Sommerville, Kenneth W., Wolfram, Gernot
Publicado 2017

Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations

por Tarabar, Sanela, Kelsh, Debra, Vince, Bradley, Leyva, Rina, Song, Dongweon, Matschke, Kyle, Kellstein, David E., Meeves, Suzanne, Cruz-Rivera, Mario
Publicado 2020

Effect of Food on the Pharmacokinetics of Ertugliflozin and Its Fixed‐Dose Combinations Ertugliflozin/Sitagliptin and Ertugliflozin/Metformin

por Sahasrabudhe, Vaishali, Fediuk, Daryl J., Matschke, Kyle, Shi, Haihong, Liang, Yali, Hickman, Anne, Bass, Almasa, Terra, Steven G., Zhou, Susan, Krishna, Rajesh, Dawra, Vikas K.
Publicado 2018

Bioequivalence of Ertugliflozin/Sitagliptin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components

por Fediuk, Daryl J., Matschke, Kyle, Liang, Yali, Pelletier, Kathleen B., Wei, Hua, Shi, Haihong, Bass, Almasa, Hickman, Anne, Terra, Steven G., Zhou, Susan, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicado 2019

Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin

por Raje, Sangeeta, Callegari, Ernesto, Sahasrabudhe, Vaishali, Vaz, Alfin, Shi, Haihong, Fluhler, Eric, Woolf, Eric J., Schildknegt, Klaas, Matschke, Kyle, Alvey, Christine, Zhou, Susan, Papadopoulos, Dimitris, Fountaine, Robert, Saur, Didier, Terra, Steven G., Stevens, Lloyd, Gaunt, Daniel, Cutler, David L.
Publicado 2018