Cell Surface Expression of the Major Amyloid-β Peptide (Aβ)-degrading Enzyme, Neprilysin, Depends on Phosphorylation by Mitogen-activated Protein Kinase/Extracellular Signal-regula...

por Kakiya, Naomasa, Saito, Takashi, Nilsson, Per, Matsuba, Yukio, Tsubuki, Satoshi, Takei, Nobuyuki, Nawa, Hiroyuki, Saido, Takaomi C.
Publicado 2012

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer’s disease-like pathology

por Nagata, Kenichi, Takahashi, Mika, Matsuba, Yukio, Okuyama-Uchimura, Fumi, Sato, Kaori, Hashimoto, Shoko, Saito, Takashi, Saido, Takaomi C.
Publicado 2018

Tau binding protein CAPON induces tau aggregation and neurodegeneration

por Hashimoto, Shoko, Matsuba, Yukio, Kamano, Naoko, Mihira, Naomi, Sahara, Naruhiko, Takano, Jiro, Muramatsu, Shin-ichi, Saido, Takaomi C., Saito, Takashi
Publicado 2019

Author Correction: Tau binding protein CAPON induces tau aggregation and neurodegeneration

por Hashimoto, Shoko, Matsuba, Yukio, Kamano, Naoko, Mihira, Naomi, Sahara, Naruhiko, Takano, Jiro, Muramatsu, Shin-ichi, Saido, Takaomi C., Saito, Takashi
Publicado 2019

Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID

por Sasaguri, Hiroki, Nagata, Kenichi, Sekiguchi, Misaki, Fujioka, Ryo, Matsuba, Yukio, Hashimoto, Shoko, Sato, Kaori, Kurup, Deepika, Yokota, Takanori, Saido, Takaomi C.
Publicado 2018

Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation

por Hashimoto, Shoko, Matsuba, Yukio, Takahashi, Mika, Kamano, Naoko, Watamura, Naoto, Sasaguri, Hiroki, Takado, Yuhei, Yoshihara, Yoshihiro, Saito, Takashi, Saido, Takaomi C.
Publicado 2023

Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice

por Tachida, Yuriko, Miura, Saori, Muto, Yui, Takuwa, Hiroyuki, Sahara, Naruhiko, Shindo, Akihiro, Matsuba, Yukio, Saito, Takashi, Taniguchi, Naoyuki, Kawaguchi, Yasushi, Tomimoto, Hidekazu, Saido, Takaomi, Kitazume, Shinobu
Publicado 2022

Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor

por Maeda, Jun, Minamihisamatsu, Takeharu, Shimojo, Masafumi, Zhou, Xiaoyun, Ono, Maiko, Matsuba, Yukio, Ji, Bin, Ishii, Hideki, Ogawa, Masanao, Akatsu, Hiroyasu, Kaneda, Daita, Hashizume, Yoshio, Robinson, John L, Lee, Virginia M -Y, Saito, Takashi, Saido, Takaomi C, Trojanowski, John Q, Zhang, Ming-Rong, Suhara, Tetsuya, Higuchi, Makoto, Sahara, Naruhiko
Publicado 2021