Targeting Pyroptotic Cell Death Pathways in Retinal Disease

por Zhao, Mary, Li, Siqi, Matsubara, Joanne A.
Publicado 2022

Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN

por Xu, Qinyuan, Cao, Sijia, Rajapakse, Sanjeeva, Matsubara, Joanne A.
Publicado 2018

Purinergic signaling via P2X receptors and mechanisms of unregulated ATP release in the outer retina and age-related macular degeneration

por Molcak, Haydn, Jiang, Kailun, Campbell, Christopher J., Matsubara, Joanne A.
Publicado 2023

Immuno-modulatory Effect of IFN-gamma in AMD and its Role as a Possible Target for Therapy

por Jiang, Kailun, Cao, Sijia, Cui, Jing Z, Matsubara, Joanne A
Publicado 2013

Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye

por Gao, Jiangyuan, Cui, Jing Z., To, Eleanor, Cao, Sijia, Matsubara, Joanne A.
Publicado 2018

MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease

por Wijesinghe, Printha, Xi, Jeanne, Cui, Jing, Campbell, Matthew, Pham, Wellington, Matsubara, Joanne A
Publicado 2023

Altered cytokine profiles of human retinal pigment epithelium: Oxidant injury and replicative senescence

por Cao, Sijia, Walker, Gregory B., Wang, Xuefeng, Cui, Jing Z., Matsubara, Joanne A.
Publicado 2013

Drusen and Pro-inflammatory Mediators in the Post-Mortem Human Eye

por Jiang, Kailun, To, Eleanor, Cui, Jing Z., Cao, Sijia, Gao, Jiangyuan, Matsubara, Joanne A.
Publicado 2012

Expression of integrins on human choroidal neovascular membranes

por Cui, Jing, Maberley, David, Samad, Arif, Ma, Patrick, Ning, Allison, Matsubara, Joanne A., Baciu, Peter
Publicado 2009

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

por Gao, Jiangyuan, Liu, Ruozhou Tom, Cao, Sijia, Cui, Jing Z., Wang, Aikun, To, Eleanor, Matsubara, Joanne A.
Publicado 2015

The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis

por Gao, Jiangyuan, Cui, Jing Z., Wang, Aikun, Chen, Hao Hang Rachel, Fong, Alison, Matsubara, Joanne A.
Publicado 2019

Inhalable Thioflavin S for the Detection of Amyloid Beta Deposits in the Retina

por Barton, Shawn M., To, Eleanor, Rogers, Baxter P., Whitmore, Clayton, Uppal, Manjosh, Matsubara, Joanne A., Pham, Wellington
Publicado 2021

Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy

por Dubchak, Eden, Obasanmi, Gideon, Zeglinski, Matthew R., Granville, David J., Yeung, Sonia N., Matsubara, Joanne A.
Publicado 2022

Retinal Distribution and Extracellular Activity of Granzyme B: A Serine Protease That Degrades Retinal Pigment Epithelial Tight Junctions and Extracellular Matrix Proteins

por Matsubara, Joanne A., Tian, Yuan, Cui, Jing Z., Zeglinski, Matthew R., Hiroyasu, Sho, Turner, Christopher T., Granville, David J.
Publicado 2020

Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer’s disease

por Wijesinghe, Printha, Whitmore, Clayton A., Campbell, Matthew, Li, Charles, Tsuyuki, Miranda, To, Eleanor, Haynes, Justin, Pham, Wellington, Matsubara, Joanne A.
Publicado 2023

In vivo Retinal Fluorescence Imaging With Curcumin in an Alzheimer Mouse Model

por Sidiqi, Ahmad, Wahl, Daniel, Lee, Sieun, Ma, Da, To, Elliott, Cui, Jing, To, Eleanor, Beg, Mirza Faisal, Sarunic, Marinko, Matsubara, Joanne A.
Publicado 2020

CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye

por Wang, Jay Ching Chieh, Cao, Sijia, Wang, Aikun, To, Eleanor, Law, Geoffrey, Gao, Jiangyuan, Zhang, Dean, Cui, Jing Z., Matsubara, Joanne A.
Publicado 2015

Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye

por Zhao, Tom, Gao, Jiangyuan, Van, Jenifer, To, Eleanor, Wang, Aikun, Cao, Sijia, Cui, Jing Z., Guo, Jian-Ping, Lee, Moonhee, McGeer, Patrick L., Matsubara, Joanne A.
Publicado 2015

Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy

por Zhou, Guohong, Duan, Yajiang, Ma, Gaoen, Wu, Wenyi, Hu, Zhengping, Chen, Na, Chee, Yewlin, Cui, Jing, Samad, Arif, Matsubara, Joanne A., Mukai, Shizuo, D'Amore, Patricia A., Lei, Hetian
Publicado 2017

Amyloid Beta Immunoreactivity in the Retinal Ganglion Cell Layer of the Alzheimer’s Eye

por Lee, Sieun, Jiang, Kailun, McIlmoyle, Brandon, To, Eleanor, Xu, Qinyuan (Alis), Hirsch-Reinshagen, Veronica, Mackenzie, Ian R., Hsiung, Ging-Yuek R., Eadie, Brennan D., Sarunic, Marinko V., Beg, Mirza Faisal, Cui, Jing Z., Matsubara, Joanne A.
Publicado 2020