Phase III, multicenter, open-label, long-term study of the safety of abatacept in Japanese patients with rheumatoid arthritis and an inadequate response to conventional or biologic...

por Takeuchi, Tsutomu, Matsubara, Tsukasa, Urata, Yukitomo, Suematsu, Eiichi, Ohta, Shuji, Honjo, Shigeru, Abe, Tohru, Yamamoto, Ami, Miyasaka, Nobuyuki
Publicado 2014

Biologic-free remission of established rheumatoid arthritis after discontinuation of abatacept: a prospective, multicentre, observational study in Japan

por Takeuchi, Tsutomu, Matsubara, Tsukasa, Ohta, Shuji, Mukai, Masaya, Amano, Koichi, Tohma, Shigeto, Tanaka, Yoshiya, Yamanaka, Hisashi, Miyasaka, Nobuyuki
Publicado 2015

A genome-wide association study identifying the SNPs predictive of rapid joint destruction in patients with rheumatoid arthritis

por Hayashi, Shinya, Matsubara, Tsukasa, Fukuda, Koji, Maeda, Toshihisa, Funahashi, Keiko, Hashimoto, Marowa, Kamenaga, Tomoyuki, Takashima, Yoshinori, Kuroda, Ryosuke
Publicado 2021

Geographic Analysis of the Safety and Efficacy of Filgotinib in Rheumatoid Arthritis

por Combe, Bernard, Besuyen, Robin, Gómez-Centeno, Antonio, Matsubara, Tsukasa, Sancho Jimenez, Juan José, Yin, Zhaoyu, Buch, Maya H.
Publicado 2022

Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis

por Koike, Ryuji, Harigai, Masayoshi, Atsumi, Tatsuya, Amano, Koichi, Kawai, Shinichi, Saito, Kazuyoshi, Saito, Tomoyuki, Yamamura, Masahiro, Matsubara, Tsukasa, Miyasaka, Nobuyuki
Publicado 2009

ARG098, a novel anti-human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient-HuRAg mouse model

por Odani-Kawabata, Noriko, Takai-Imamura, Miwa, Katsuta, Osamu, Nakamura, Hiroshi, Nishioka, Kusuki, Funahashi, Keiko, Matsubara, Tsukasa, Sasano, Minoru, Aono, Hiroyuki
Publicado 2010

Accelerated Development of Cervical Spine Instabilities in Rheumatoid Arthritis: A Prospective Minimum 5-Year Cohort Study

por Yurube, Takashi, Sumi, Masatoshi, Nishida, Kotaro, Miyamoto, Hiroshi, Kohyama, Kozo, Matsubara, Tsukasa, Miura, Yasushi, Hirata, Hiroaki, Sugiyama, Daisuke, Doita, Minoru
Publicado 2014

Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results...

por Yamanaka, Hisashi, Ishiguro, Naoki, Takeuchi, Tsutomu, Miyasaka, Nobuyuki, Mukai, Masaya, Matsubara, Tsukasa, Uchida, Shoji, Akama, Hideto, Kupper, Hartmut, Arora, Vipin, Tanaka, Yoshiya
Publicado 2014

Adalimumab, a human anti-TNF monoclonal antibody, outcome study for the prevention of joint damage in Japanese patients with early rheumatoid arthritis: the HOPEFUL 1 study

por Takeuchi, Tsutomu, Yamanaka, Hisashi, Ishiguro, Naoki, Miyasaka, Nobuyuki, Mukai, Masaya, Matsubara, Tsukasa, Uchida, Shoji, Akama, Hideto, Kupper, Hartmut, Arora, Vipin, Tanaka, Yoshiya
Publicado 2014

Predictive factors for effective selection of Interleukin-6 inhibitor and tumor necrosis factor inhibitor in the treatment of rheumatoid arthritis

por Hayashi, Shinya, Matsubara, Tsukasa, Fukuda, Koji, Funahashi, Keiko, Hashimoto, Marowa, Maeda, Toshihisa, Kamenaga, Tomoyuki, Takashima, Yoshinori, Matsumoto, Tomoyuki, Niikura, Takahiro, Kuroda, Ryosuke
Publicado 2020

A genome-wide association study identifying single nucleotide polymorphisms in the PPFIBP2 gene was predictive for interstitial lung disease in rheumatoid arthritis patients

por Hayashi, Shinya, Matsubara, Tsukasa, Fukuda, Koji, Maeda, Toshihisa, Funahashi, Keiko, Hashimoto, Marowa, Takashima, Yoshinori, Kikuchi, Kenichi, Fujita, Masahiro, Matsumoto, Tomoyuki, Kuroda, Ryosuke
Publicado 2022

Comparison of the inhibitory effect of tocilizumab and etanercept on the progression of joint erosion in rheumatoid arthritis treatment

por Hayashi, Shinya, Matsubara, Tsukasa, Maeda, Toshihisa, Fukuda, Koji, Funahashi, Keiko, Hashimoto, Marowa, Tsumiyama, Ken, Kamenaga, Tomoyuki, Takashima, Yoshinori, Matsumoto, Tomoyuki, Tachibana, Shotaro, Kuroda, Ryosuke
Publicado 2022

SNP algorithms for prediction of efficacy and adverse events of abatacept (ABT)

por Middleton, James E, Matsubara, Tsukasa, Funahashi, Keiko, Koyano, Satoru, Hagiwara, Takafumi, Miura, Takako, Okuda, Kosuke, Nakamura, Takeshi, Iwahashi, Mitsuyoshi, Tsuru, Tomomi, Uchimura, Shoichi, Honjo, Shigeru
Publicado 2012

Phase III Study of the Efficacy and Safety of Subcutaneous Versus Intravenous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis

por Ogata, Atsushi, Tanimura, Kazuhide, Sugimoto, Toyohiko, Inoue, Hiroshi, Urata, Yukitomo, Matsubara, Tsukasa, Kondo, Masakazu, Ueki, Yukitaka, Iwahashi, Mitsuhiro, Tohma, Shigeto, Ohta, Shuji, Saeki, Yukihiko, Tanaka, Toshio
Publicado 2014

Abatacept in combination with methotrexate in Japanese biologic-naive patients with active rheumatoid arthritis: a randomised placebo-controlled phase IV study

por Matsubara, Tsukasa, Inoue, Hiroshi, Nakajima, Toshihiro, Tanimura, Kazuhide, Sagawa, Akira, Sato, Yukio, Osano, Kei, Nagano, Shuji, Ueki, Yukitaka, Hanyu, Tadamasa, Hashizume, Koichi, Amano, Norihito, Tanaka, Yoshiya, Takeuchi, Tsutomu
Publicado 2018

Real-World Methotrexate Dose on Clinical Effectiveness and Structural Damage of Certolizumab Pegol With Rheumatoid Arthritis

por Nozaki, Yuji, Hidaka, Toshihiko, Ri, Jinhai, Itami, Tetsu, Tomita, Daisuke, Okada, Akinori, Ashida, Chisato, Ikeda, Fusayo, Yamamoto, Atsuhiro, Funahashi, Keiko, Kinoshita, Koji, Matsubara, Tsukasa, Funauchi, Masanori, Matsumura, Itaru
Publicado 2021

Effect of nutritional counseling and long term isomaltulose based liquid formula (MHN-01) intake on metabolic syndrome

por Takeda, Eiji, Yamanaka-Okumura, Hisami, Taketani, Yutaka, Inagaki, Nobuya, Hosokawa, Masaya, Shide, Kenichiro, Maegawa, Hiroshi, Kondo, Keiko, Kawasaki, Eiji, Shinozaki, Shoko, Fujinaka, Yuichi, Matsubara, Tsukasa, Katayama, Takafumi, Sasaki, Hajime, Kawashima, Akihiro, Aonuma, Hiromitsu
Publicado 2015

The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows i...

por Atsumi, Tatsuya, Yamamoto, Kazuhiko, Takeuchi, Tsutomu, Yamanaka, Hisashi, Ishiguro, Naoki, Tanaka, Yoshiya, Eguchi, Katsumi, Watanabe, Akira, Origasa, Hideki, Yasuda, Shinsuke, Yamanishi, Yuji, Kita, Yasuhiko, Matsubara, Tsukasa, Iwamoto, Masahiro, Shoji, Toshiharu, Okada, Toshiyuki, van der Heijde, Désirée, Miyasaka, Nobuyuki, Koike, Takao
Publicado 2016

Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation:...

por Atsumi, Tatsuya, Tanaka, Yoshiya, Yamamoto, Kazuhiko, Takeuchi, Tsutomu, Yamanaka, Hisashi, Ishiguro, Naoki, Eguchi, Katsumi, Watanabe, Akira, Origasa, Hideki, Yasuda, Shinsuke, Yamanishi, Yuji, Kita, Yasuhiko, Matsubara, Tsukasa, Iwamoto, Masahiro, Shoji, Toshiharu, Togo, Osamu, Okada, Toshiyuki, van der Heijde, Désirée, Miyasaka, Nobuyuki, Koike, Takao
Publicado 2017

DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus

por Shiozawa, Shunichi, Tsumiyama, Ken, Miyazaki, Yumi, Uto, Kenichi, Sakurai, Keiichi, Nakashima, Toshie, Matsuyama, Hiroko, Doi, Ai, Tarui, Miho, Izumikawa, Manabu, Kimura, Mai, Fujita, Yuko, Satonaka, Chisako, Horiuchi, Takahiko, Matsubara, Tsukasa, Oribe, Motohiro, Yamane, Takashi, Kagawa, Hidetoshi, Li, Quan-Zhen, Mizuno, Keiko, Mukai, Yohei, Murakami, Kazuhiro, Enya, Takuji, Tsukimoto, Shota, Hakata, Yoshiyuki, Miyazawa, Masaaki, Shiozawa, Kazuko
Publicado 2021