Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification

por Matsuo, Shiori, Nishinaka-Arai, Yoko, Kazuki, Yasuhiro, Oshimura, Mitsuo, Nakahata, Tatsutoshi, Niwa, Akira, Saito, Megumu K.
Publicado 2021

Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations

por Grajcarek, Janin, Monlong, Jean, Nishinaka-Arai, Yoko, Nakamura, Michiko, Nagai, Miki, Matsuo, Shiori, Lougheed, David, Sakurai, Hidetoshi, Saito, Megumu K., Bourque, Guillaume, Woltjen, Knut
Publicado 2019

Down syndrome-related transient abnormal myelopoiesis is attributed to a specific erythro-megakaryocytic subpopulation with GATA1 mutation

por Nishinaka-Arai, Yoko, Niwa, Akira, Matsuo, Shiori, Kazuki, Yasuhiro, Yakura, Yuwna, Hiroma, Takehiko, Toki, Tsutomu, Sakuma, Tetsushi, Yamamoto, Takashi, Ito, Etsuro, Oshimura, Mitsuo, Nakahata, Tatsutoshi, Saito, Megumu K.
Publicado 2020