Molecular dynamics simulations reveal the importance of amyloid-beta oligomer β-sheet edge conformations in membrane permeabilization

por Matthes, Dirk, de Groot, Bert L.
Publicado 2023

Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization

por Matthes, Dirk, Gapsys, Vytautas, Daebel, Venita, de Groot, Bert L.
Publicado 2011

An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase

por Matthes, Dirk, Gapsys, Vytautas, Brennecke, Julian T., de Groot, Bert L.
Publicado 2016

The 3D structure of lipidic fibrils of α-synuclein

por Frieg, Benedikt, Antonschmidt, Leif, Dienemann, Christian, Geraets, James A., Najbauer, Eszter E., Matthes, Dirk, de Groot, Bert L., Andreas, Loren B., Becker, Stefan, Griesinger, Christian, Schröder, Gunnar F.
Publicado 2022

The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils

por Antonschmidt, Leif, Matthes, Dirk, Dervişoğlu, Rıza, Frieg, Benedikt, Dienemann, Christian, Leonov, Andrei, Nimerovsky, Evgeny, Sant, Vrinda, Ryazanov, Sergey, Giese, Armin, Schröder, Gunnar F., Becker, Stefan, de Groot, Bert L., Griesinger, Christian, Andreas, Loren B.
Publicado 2022