Variable Responses to CFTR Correctors in vitro: Estimating the Design Effect in Precision Medicine

por Matthes, Elizabeth, Goepp, Julie, Martini, Carolina, Shan, Jiajie, Liao, Jie, Thomas, David Y., Hanrahan, John W.
Publicado 2018

A novel triple combination of pharmacological chaperones improves F508del-CFTR correction

por Carlile, Graeme W., Yang, Qi, Matthes, Elizabeth, Liao, Jie, Radinovic, Stevo, Miyamoto, Carol, Robert, Renaud, Hanrahan, John W., Thomas, David Y.
Publicado 2018

Hsp70 and DNAJA2 limit CFTR levels through degradation

por Kim Chiaw, Patrick, Hantouche, Christine, Wong, Michael J. H., Matthes, Elizabeth, Robert, Renaud, Hanrahan, John W., Shrier, Alvin, Young, Jason C.
Publicado 2019

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway

por Carlile, Graeme W., Yang, Qi, Matthes, Elizabeth, Liao, Jie, Birault, Véronique, Sneddon, Helen F., Poole, Darren L., Hall, Callum J., Hanrahan, John W., Thomas, David Y.
Publicado 2022

Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity

por Armirotti, Andrea, Tomati, Valeria, Matthes, Elizabeth, Veit, Guido, Cholon, Deborah M., Phuan, Puay-Wah, Braccia, Clarissa, Guidone, Daniela, Gentzsch, Martina, Lukacs, Gergely L., Verkman, Alan S., Galietta, Luis J. V., Hanrahan, John W., Pedemonte, Nicoletta
Publicado 2019