Role of Polycomb Group Proteins in the DNA Damage Response – A Reassessment

por Chandler, Hollie, Patel, Harshil, Palermo, Richard, Brookes, Sharon, Matthews, Nik, Peters, Gordon
Publicado 2014

SRF Co-factors Control the Balance between Cell Proliferation and Contractility

por Gualdrini, Francesco, Esnault, Cyril, Horswell, Stuart, Stewart, Aengus, Matthews, Nik, Treisman, Richard
Publicado 2016

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

por Esnault, Cyril, Stewart, Aengus, Gualdrini, Francesco, East, Phil, Horswell, Stuart, Matthews, Nik, Treisman, Richard
Publicado 2014

Hmga2 functions as a competing endogenous RNA to promote lung cancer progression

por Kumar, Madhu S., Armenteros-Monterroso, Elena, East, Philip, Chakravorty, Probir, Matthews, Nik, Winslow, Monte M., Downward, Julian
Publicado 2013

ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

por Esnault, Cyril, Gualdrini, Francesco, Horswell, Stuart, Kelly, Gavin, Stewart, Aengus, East, Phil, Matthews, Nik, Treisman, Richard
Publicado 2017

Retention of the Native Epigenome in Purified Mammalian Chromatin

por Ehrensberger, Andreas H., Franchini, Don-Marc, East, Philip, George, Roger, Matthews, Nik, Maslen, Sarah L., Svejstrup, Jesper Q.
Publicado 2015

Correction: Retention of the Native Epigenome in Purified Mammalian Chromatin

por Ehrensberger, Andreas H., Franchini, Don-Marc, East, Philip, George, Roger, Matthews, Nik, Maslen, Sarah L., Svejstrup, Jesper Q.
Publicado 2015

Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling

por Coda, Davide M, Gaarenstroom, Tessa, East, Philip, Patel, Harshil, Miller, Daniel S J, Lobley, Anna, Matthews, Nik, Stewart, Aengus, Hill, Caroline S
Publicado 2017

A simple biophysical model emulates budding yeast chromosome condensation

por Cheng, Tammy MK, Heeger, Sebastian, Chaleil, Raphaël AG, Matthews, Nik, Stewart, Aengus, Wright, Jon, Lim, Carmay, Bates, Paul A, Uhlmann, Frank
Publicado 2015

Predicting Response to Radical Chemoradiotherapy with Circulating HPV DNA (cHPV-DNA) in Locally Advanced Uterine Cervix Cancer

por Lalondrelle, Susan, Lee, Jen, Cutts, Rosalind J., Garcia Murillas, Isaac, Matthews, Nik, Turner, Nicholas, Harrington, Kevin, Vroobel, Katherine, Moretti, Emily, Bhide, Shreerang A.
Publicado 2023

Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer

por Woolston, Andrew, Barber, Louise J, Griffiths, Beatrice, Pich, Oriol, Lopez-Bigas, Nuria, Matthews, Nik, Rao, Sheela, Watkins, David, Chau, Ian, Starling, Naureen, Cunningham, David, Gerlinger, Marco
Publicado 2021

Mutation of cancer driver MLL2 results in transcription stress and genome instability

por Kantidakis, Theodoros, Saponaro, Marco, Mitter, Richard, Horswell, Stuart, Kranz, Andrea, Boeing, Stefan, Aygün, Ozan, Kelly, Gavin P., Matthews, Nik, Stewart, Aengus, Stewart, A. Francis, Svejstrup, Jesper Q.
Publicado 2016

Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC)

por Lee, Jen Y., Cutts, Rosalind J., White, Ingrid, Augustin, Yolanda, Garcia-Murillas, Isaac, Fenwick, Kerry, Matthews, Nik, Turner, Nicholas C., Harrington, Kevin, Gilbert, Duncan C., Bhide, Shreerang
Publicado 2020

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

por Deddouche, Safia, Goubau, Delphine, Rehwinkel, Jan, Chakravarty, Probir, Begum, Sharmin, Maillard, Pierre V, Borg, Annabel, Matthews, Nik, Feng, Qian, van Kuppeveld, Frank J M, Reis e Sousa, Caetano
Publicado 2014

Genome-wide co-localization of Polycomb orthologs and their effects on gene expression in human fibroblasts

por Pemberton, Helen, Anderton, Emma, Patel, Harshil, Brookes, Sharon, Chandler, Hollie, Palermo, Richard, Stock, Julie, Rodriguez-Niedenführ, Marc, Racek, Tomas, de Breed, Lucas, Stewart, Aengus, Matthews, Nik, Peters, Gordon
Publicado 2014

Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

por von Loga, Katharina, Woolston, Andrew, Punta, Marco, Barber, Louise J., Griffiths, Beatrice, Semiannikova, Maria, Spain, Georgia, Challoner, Benjamin, Fenwick, Kerry, Simon, Ronald, Marx, Andreas, Sauter, Guido, Lise, Stefano, Matthews, Nik, Gerlinger, Marco
Publicado 2020

Author Correction: Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

por von Loga, Katharina, Woolston, Andrew, Punta, Marco, Barber, Louise J., Griffiths, Beatrice, Semiannikova, Maria, Spain, Georgia, Challoner, Benjamin, Fenwick, Kerry, Simon, Ronald, Marx, Andreas, Sauter, Guido, Lise, Stefano, Matthews, Nik, Gerlinger, Marco
Publicado 2020

Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma

por Davidson, Michael, Barber, Louise J., Woolston, Andrew, Cafferkey, Catherine, Mansukhani, Sonia, Griffiths, Beatrice, Moorcraft, Sing-Yu, Rana, Isma, Begum, Ruwaida, Assiotis, Ioannis, Matthews, Nik, Rao, Sheela, Watkins, David, Chau, Ian, Cunningham, David, Starling, Naureen, Gerlinger, Marco
Publicado 2019

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

por Newey, Alice, Griffiths, Beatrice, Michaux, Justine, Pak, Hui Song, Stevenson, Brian J., Woolston, Andrew, Semiannikova, Maria, Spain, Georgia, Barber, Louise J., Matthews, Nik, Rao, Sheela, Watkins, David, Chau, Ian, Coukos, George, Racle, Julien, Gfeller, David, Starling, Naureen, Cunningham, David, Bassani-Sternberg, Michal, Gerlinger, Marco
Publicado 2019

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing

por Chong, Irene Y., Starling, Naureen, Rust, Alistair, Alexander, John, Aronson, Lauren, Llorca-Cardenosa, Marta, Chauhan, Ritika, Chaudry, Asif, Kumar, Sacheen, Fenwick, Kerry, Assiotis, Ioannis, Matthews, Nik, Begum, Ruwaida, Wotherspoon, Andrew, Terlizzo, Monica, Watkins, David, Chau, Ian, Lord, Christopher J., Haider, Syed, Rao, Sheela, Cunningham, David
Publicado 2021