The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia

por Ralvenius, William T., Acuña, Mario A., Benke, Dietmar, Matthey, Alain, Daali, Youssef, Rudolph, Uwe, Desmeules, Jules, Zeilhofer, Hanns Ulrich, Besson, Marie
Publicado 2016

Uncovering a Genetic Polymorphism Located in Huntingtin Associated Protein 1 in Modulation of Central Pain Sensitization Signaling Pathways

por Gloor, Yvonne, Matthey, Alain, Sobo, Komla, Mouterde, Médéric, Kosek, Eva, Pickering, Gisèle, Poloni, Estella S., Cedraschi, Christine, Ehret, Georg, Desmeules, Jules A.
Publicado 2022

Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity

por Magliocco, Gaëlle, Desmeules, Jules, Matthey, Alain, Quirós‐Guerrero, Luis M., Bararpour, Nasim, Joye, Timothée, Marcourt, Laurence, Queiroz, Emerson F., Wolfender, Jean‐Luc, Gloor, Yvonne, Thomas, Aurélien, Daali, Youssef
Publicado 2021