Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms

por Lai, Louis Tung Faat, Balaraman, Jayashree, Zhou, Fei, Matthies, Doreen
Publicado 2023

Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms

por Lai, Louis Tung Faat, Balaraman, Jayashree, Zhou, Fei, Matthies, Doreen
Publicado 2023

Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport

por Qiu, Biao, Matthies, Doreen, Fortea, Eva, Yu, Zhiheng, Boudker, Olga
Publicado 2021

The crystal structure of human GlnRS provides basis for the development of neurological disorders

por Ognjenović, Jana, Wu, Jiang, Matthies, Doreen, Baxa, Ulrich, Subramaniam, Sriram, Ling, Jiqiang, Simonović, Miljan
Publicado 2016

Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase

por Puppala, Anupama K., French, Rachel L., Matthies, Doreen, Baxa, Ulrich, Subramaniam, Sriram, Simonović, Miljan
Publicado 2016

The Delta variant SARS-CoV-2 spike protein uniquely promotes aggregation of pseudotyped viral particles

por Petersen, Jennifer D., Lu, Jianming, Fitzgerald, Wendy, Zhou, Fei, Blank, Paul S., Matthies, Doreen, Zimmerberg, Joshua
Publicado 2022

Unique Aggregation of Retroviral Particles Pseudotyped with the Delta Variant SARS-CoV-2 Spike Protein

por Petersen, Jennifer D., Lu, Jianming, Fitzgerald, Wendy, Zhou, Fei, Blank, Paul S., Matthies, Doreen, Zimmerberg, Joshua
Publicado 2022

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs

por Matthies, Doreen, Bae, Chanhyung, Toombes, Gilman ES, Fox, Tara, Bartesaghi, Alberto, Subramaniam, Sriram, Swartz, Kenton Jon
Publicado 2018

Lipid flipping in the omega-3 fatty-acid transporter

por Nguyen, Chi, Lei, Hsiang-Ting, Lai, Louis Tung Faat, Gallenito, Marc J., Mu, Xuelang, Matthies, Doreen, Gonen, Tamir
Publicado 2023

High-Resolution Structure and Mechanism of an F/V-Hybrid Rotor Ring in a Na(+)-coupled ATP Synthase

por Matthies, Doreen, Zhou, Wenchang, Klyszejko, Adriana L., Anselmi, Claudio, Yildiz, Özkan, Brandt, Karsten, Müller, Volker, Faraldo-Gómez, José D., Meier, Thomas
Publicado 2014

A New Type of Na(+)-Driven ATP Synthase Membrane Rotor with a Two-Carboxylate Ion-Coupling Motif

por Schulz, Sarah, Iglesias-Cans, Marina, Krah, Alexander, Yildiz, Özkan, Leone, Vanessa, Matthies, Doreen, Cook, Gregory M., Faraldo-Gómez, José D., Meier, Thomas
Publicado 2013

Microdomains form on the luminal face of neuronal extracellular vesicle membranes

por Matthies, Doreen, Lee, Nathanael Y. J., Gatera, Ian, Pasolli, H. Amalia, Zhao, Xiaowei, Liu, Hui, Walpita, Deepika, Liu, Zhe, Yu, Zhiheng, Ioannou, Maria S.
Publicado 2020

Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase

por Borgnia, Mario J., Banerjee, Soojay, Merk, Alan, Matthies, Doreen, Bartesaghi, Alberto, Rao, Prashant, Pierson, Jason, Earl, Lesley A., Falconieri, Veronica, Subramaniam, Sriram, Milne, Jacqueline L. S.
Publicado 2016

Autolysosomal exocytosis of lipids protect neurons from ferroptosis

por Ralhan, Isha, Chang, Jinlan, Moulton, Matthew J., Goodman, Lindsey D., Lee, Nathanael Y.J., Plummer, Greg, Pasolli, H. Amalia, Matthies, Doreen, Bellen, Hugo J., Ioannou, Maria S.
Publicado 2023

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

por Prévost, Jérémie, Chen, Yaozong, Zhou, Fei, Tolbert, William D., Gasser, Romain, Medjahed, Halima, Nayrac, Manon, Nguyen, Dung N., Gottumukkala, Suneetha, Hessell, Ann J., Rao, Venigalla B., Pozharski, Edwin, Huang, Rick K., Matthies, Doreen, Finzi, Andrés, Pazgier, Marzena
Publicado 2023

The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins

por Miller, Alexandria N, Houlihan, Patrick R, Matamala, Ella, Cabezas-Bratesco, Deny, Lee, Gi Young, Cristofori-Armstrong, Ben, Dilan, Tanya L, Sanchez-Martinez, Silvia, Matthies, Doreen, Yan, Rui, Yu, Zhiheng, Ren, Dejian, Brauchi, Sebastian E, Clapham, David E
Publicado 2023

The Structural Basis of Rubisco Phase Separation in the Pyrenoid

por He, Shan, Chou, Hui-Ting, Matthies, Doreen, Wunder, Tobias, Meyer, Moritz T., Atkinson, Nicky, Martinez-Sanchez, Antonio, Jeffrey, Philip D., Port, Sarah A., Patena, Weronika, He, Guanhua, Chen, Vivian K., Hughson, Frederick M., McCormick, Alistair J., Mueller-Cajar, Oliver, Engel, Benjamin D., Yu, Zhiheng, Jonikas, Martin C.
Publicado 2020

Allosteric interactions prime androgen receptor dimerization and activation

por Wasmuth, Elizabeth V., Vanden Broeck, Arnaud, LaClair, Justin R., Hoover, Elizabeth A., Lawrence, Kayla E., Paknejad, Navid, Pappas, Kyrie, Matthies, Doreen, Wang, Biran, Feng, Weiran, Watson, Philip A., Zinder, John C., Karthaus, Wouter R., de la Cruz, M. Jason, Hite, Richard K., Manova-Todorova, Katia, Yu, Zhiheng, Weintraub, Susan T., Klinge, Sebastian, Sawyers, Charles L.
Publicado 2022

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

por Chen, Yaozong, Prévost, Jérémie, Ullah, Irfan, Romero, Hugo, Lisi, Veronique, Tolbert, William D., Grover, Jonathan R., Ding, Shilei, Gong, Shang Yu, Beaudoin-Bussières, Guillaume, Gasser, Romain, Benlarbi, Mehdi, Vézina, Dani, Anand, Sai Priya, Chatterjee, Debashree, Goyette, Guillaume, Grunst, Michael W., Yang, Ziwei, Bo, Yuxia, Zhou, Fei, Béland, Kathie, Bai, Xiaoyun, Zeher, Allison R., Huang, Rick K., Nguyen, Dung N., Sherburn, Rebekah, Wu, Di, Piszczek, Grzegorz, Paré, Bastien, Matthies, Doreen, Xia, Di, Richard, Jonathan, Kumar, Priti, Mothes, Walther, Côté, Marceline, Uchil, Pradeep D., Lavallée, Vincent-Philippe, Smith, Martin A., Pazgier, Marzena, Haddad, Elie, Finzi, Andrés
Publicado 2022