Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels

por Matz-Soja, Madlen, Aleithe, Susanne, Marbach, Eugenia, Böttger, Jan, Arnold, Katrin, Schmidt-Heck, Wolfgang, Kratzsch, Jürgen, Gebhardt, Rolf
Publicado 2014

The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism – A Systems Biology Analysis Using Self-Organizing Maps

por Rennert, Christiane, Vlaic, Sebastian, Marbach-Breitrück, Eugenia, Thiel, Carlo, Sales, Susanne, Shevchenko, Andrej, Gebhardt, Rolf, Matz-Soja, Madlen
Publicado 2018

Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver

por Spormann, Luise, Rennert, Christiane, Kolbe, Erik, Ott, Fritzi, Lossius, Carolin, Lehmann, Robert, Gebhardt, Rolf, Berg, Thomas, Matz-Soja, Madlen
Publicado 2020

In Vivo and In Vitro Characterization of Primary Human Liver Macrophages and Their Inflammatory State

por Zimmermann, Andrea, Hänsel, René, Gemünden, Kilian, Kegel-Hübner, Victoria, Babel, Jonas, Bläker, Hendrik, Matz-Soja, Madlen, Seehofer, Daniel, Damm, Georg
Publicado 2021

The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes

por Vlaic, Sebastian, Schmidt-Heck, Wolfgang, Matz-Soja, Madlen, Marbach, Eugenia, Linde, Jörg, Meyer-Baese, Anke, Zellmer, Sebastian, Guthke, Reinhard, Gebhardt, Rolf
Publicado 2012

Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer

por Cokan, Kaja Blagotinšek, Urlep, Žiga, Lorbek, Gregor, Matz-Soja, Madlen, Skubic, Cene, Perše, Martina, Jeruc, Jera, Juvan, Peter, Režen, Tadeja, Rozman, Damjana
Publicado 2020

Sex-dependent dynamics of metabolism in primary mouse hepatocytes

por Hochmuth, Luise, Körner, Christiane, Ott, Fritzi, Volke, Daniela, Cokan, Kaja Blagotinšek, Juvan, Peter, Brosch, Mario, Hofmann, Ute, Hoffmann, Ralf, Rozman, Damjana, Berg, Thomas, Matz-Soja, Madlen
Publicado 2021

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling

por Urlep, Žiga, Lorbek, Gregor, Perše, Martina, Jeruc, Jera, Juvan, Peter, Matz-Soja, Madlen, Gebhardt, Rolf, Björkhem, Ingemar, Hall, Jason A., Bonneau, Richard, Littman, Dan R., Rozman, Damjana
Publicado 2017

Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21

por Ott, Fritzi, Körner, Christiane, Werner, Kim, Gericke, Martin, Liebscher, Ines, Lobsien, Donald, Radrezza, Silvia, Shevchenko, Andrej, Hofmann, Ute, Kratzsch, Jürgen, Gebhardt, Rolf, Berg, Thomas, Matz-Soja, Madlen
Publicado 2022

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

por Matz-Soja, Madlen, Rennert, Christiane, Schönefeld, Kristin, Aleithe, Susanne, Boettger, Jan, Schmidt-Heck, Wolfgang, Weiss, Thomas S, Hovhannisyan, Amalya, Zellmer, Sebastian, Klöting, Nora, Schulz, Angela, Kratzsch, Jürgen, Guthke, Reinhardt, Gebhardt, Rolf
Publicado 2016

Dickkopf-Related Protein 1 as Response Marker for Transarterial Chemoembolization of Hepatocellular Carcinomas

por Olbrich, Anne, Gros, Olga, Ebel, Sebastian, Denecke, Timm, Gößmann, Holger, Linder, Nicolas, Lordick, Florian, Forstmeyer, Dirk, Seehofer, Daniel, Sucher, Robert, Rademacher, Sebastian, Niemeyer, Johannes, Matz-Soja, Madlen, Berg, Thomas, van Bömmel, Florian
Publicado 2022

Genetic Variation of SAMM50 Is Not an Independent Risk Factor for Alcoholic Hepatocellular Carcinoma in Caucasian Patients

por Nischalke, Hans Dieter, Schmalz, Franziska, Buch, Stephan, Fischer, Janett, Möller, Christine, Matz-Soja, Madlen, Krämer, Benjamin, Langhans, Bettina, Klüners, Alexandra, Soyka, Michael, Stickel, Felix, Nattermann, Jacob, Berg, Thomas, Strassburg, Christian P., Lutz, Philipp
Publicado 2022

High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis

por Schmalz, Franziska, Fischer, Janett, Innes, Hamish, Buch, Stephan, Möller, Christine, Matz-Soja, Madlen, von Schönfels, Witigo, Krämer, Benjamin, Langhans, Bettina, Klüners, Alexandra, Soyka, Michael, Stickel, Felix, Nattermann, Jacob, Strassburg, Christian P., Berg, Thomas, Lutz, Philipp, Nischalke, Hans Dieter
Publicado 2023

Influence of Liver Fibrosis on Lobular Zonation

por Ghallab, Ahmed, Myllys, Maiju, H. Holland, Christian, Zaza, Ayham, Murad, Walaa, Hassan, Reham, A. Ahmed, Yasser, Abbas, Tahany, A. Abdelrahim, Eman, Schneider, Kai Markus, Matz-Soja, Madlen, Reinders, Jörg, Gebhardt, Rolf, Berres, Marie-Luise, Hatting, Maximilian, Drasdo, Dirk, Saez-Rodriguez, Julio, Trautwein, Christian, G. Hengstler, Jan
Publicado 2019

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

por Brosch, Mario, Kattler, Kathrin, Herrmann, Alexander, von Schönfels, Witigo, Nordström, Karl, Seehofer, Daniel, Damm, Georg, Becker, Thomas, Zeissig, Sebastian, Nehring, Sophie, Reichel, Fabian, Moser, Vincent, Thangapandi, Raghavan Veera, Stickel, Felix, Baretton, Gustavo, Röcken, Christoph, Muders, Michael, Matz-Soja, Madlen, Krawczak, Michael, Gasparoni, Gilles, Hartmann, Hella, Dahl, Andreas, Schafmayer, Clemens, Walter, Jörn, Hampe, Jochen
Publicado 2018

Loss of hepatic Mboat7 leads to liver fibrosis

por Thangapandi, Veera Raghavan, Knittelfelder, Oskar, Brosch, Mario, Patsenker, Eleonora, Vvedenskaya, Olga, Buch, Stephan, Hinz, Sebastian, Hendricks, Alexander, Nati, Marina, Herrmann, Alexander, Rekhade, Devavrat Ravindra, Berg, Thomas, Matz-Soja, Madlen, Huse, Klaus, Klipp, Edda, Pauling, Josch K, Wodke, Judith AH, Miranda Ackerman, Jacobo, von Bonin, Malte, Aigner, Elmar, Datz, Christian, von Schönfels, Witigo, Nehring, Sophie, Zeissig, Sebastian, Röcken, Christoph, Dahl, Andreas, Chavakis, Triantafyllos, Stickel, Felix, Shevchenko, Andrej, Schafmayer, Clemens, Hampe, Jochen, Subramanian, Pallavi
Publicado 2021

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado 2013