The Promise and the Hype of ‘Personalised Medicine’

por Maughan, Tim
Publicado 2017

From Rosalind Franklin to Barack Obama: Data Sharing Challenges and Solutions in Genomics and Personalised Medicine

por Lawler, Mark, Maughan, Tim
Publicado 2017

The “Molecularly Unstratified” Patient: A Focus for Moral, Psycho-Social and Societal Research

por Hordern, Joshua, Maughan, Tim, Feiler, Therese, Morrell, Liz, Horne, Rob, Sullivan, Richard
Publicado 2017

Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses

por Henderson, Raymond, French, Declan, Sullivan, Richard, Maughan, Tim, Clarke, Mike, Lawler, Mark
Publicado 2019

Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study

por Grenader, Tal, Nash, Stephen, Adams, Richard, Kaplan, Richard, Fisher, David, Maughan, Tim, Bridgewater, John
Publicado 2016

Global colorectal cancer research, 2007‐2021: Outputs and funding

por Begum, Mursheda, Lewison, Grant, Wang, Xiang, Dunne, Philip D., Maughan, Tim, Sullivan, Richard, Lawler, Mark
Publicado 2022

Incorporating oxygenation levels in analytical DNA-damage models—quantifying the oxygen fixation mechanism

por Van den Heuvel, Frank, Vella, Anna, Fiorini, Francesca, Brooke, Mark, Hill, Mark A, Maughan, Tim
Publicado 2021

NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch

por O’Cathail, Séan M., Wu, Chieh-Hsi, Thomas, Rachael, Hawkins, Maria A., Maughan, Tim S., Lewis, Annabelle
Publicado 2021

Using oxygen dose histograms to quantify voxelised ultra-high dose rate (FLASH) effects in multiple radiation modalities

por Van den Heuvel, Frank, Vella, Anna, Fiorini, Francesca, Brooke, Mark, Hill, Mark, Ryan, Anderson, Maughan, Tim, Giaccia, Amato
Publicado 2022

Machine learning for normal tissue complication probability prediction: Predictive power with versatility and easy implementation

por Samant, Pratik, Ruysscher, Dirk de, Hoebers, Frank, Canters, Richard, Hall, Emma, Nutting, Chris, Maughan, Tim, Van den Heuvel, Frank
Publicado 2023

[(18)F]Fluoromisonidazole PET in rectal cancer

por Puri, Tanuj, Greenhalgh, Tessa A., Wilson, James M., Franklin, Jamie, Wang, Lia Mun, Strauss, Victoria, Cunningham, Chris, Partridge, Mike, Maughan, Tim
Publicado 2017

A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblasto...

por Brown, Nicholas F., Ng, Stasya M., Brooks, Claire, Coutts, Tim, Holmes, Jane, Roberts, Corran, Elhussein, Leena, Hoskin, Peter, Maughan, Tim, Blagden, Sarah, Mulholland, Paul
Publicado 2020

Stromal composition predicts recurrence of early rectal cancer after local excision

por Jones, Helen J S, Cunningham, Chris, Askautrud, Hanne A, Danielsen, Håvard E, Kerr, David J, Domingo, Enric, Maughan, Tim, Leedham, Simon J, Koelzer, Viktor H
Publicado 2021

A systematic review of health economic evaluations of proton beam therapy for adult cancer: Appraising methodology and quality

por Jones, David A., Smith, Joel, Mei, Xue W., Hawkins, Maria A., Maughan, Tim, van den Heuvel, Frank, Mee, Thomas, Kirkby, Karen, Kirkby, Norman, Gray, Alastair
Publicado 2019

Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer

por Leszczynska, Katarzyna B., Dobrynin, Greg, Leslie, Rhea E., Ient, Jonathan, Boumelha, Adam J., Senra, Joana M., Hawkins, Maria A., Maughan, Tim, Mukherjee, Somnath, Hammond, Ester M.
Publicado 2016

A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced...

por O’Cathail, Séan M., Davis, Steven, Holmes, Jane, Brown, Richard, Fisher, Kerry, Seymour, Leonard, Adams, Richard, Good, James, Sebag-Montefiore, David, Maughan, Tim, Hawkins, Maria A.
Publicado 2020

Importance of clinical research for the UK's 10-year cancer plan

por Lee, Richard W, Danson, Sarah, Elliot, Martin, Park, Ed I, Pinkney, Thomas D, Shaw, Clare E, Vimalachandran, Dale, Maughan, Tim, Seymour, Matt, Corrie, Pippa, Wadsley, Jonathan
Publicado 2022

Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomise...

por Wasan, Harpreet, Meade, Angela M, Adams, Richard, Wilson, Richard, Pugh, Cheryl, Fisher, David, Sydes, Benjamin, Madi, Ayman, Sizer, Bruce, Lowdell, Charles, Middleton, Gary, Butler, Rachel, Kaplan, Richard, Maughan, Tim
Publicado 2014

A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS

por Gollins, Simon, West, Nicholas, Sebag-Montefiore, David, Susnerwala, Shabbir, Falk, Stephen, Brown, Nick, Saunders, Mark, Quirke, Philip, Ray, Ruby, Parsons, Philip, Griffiths, Gareth, Maughan, Tim, Adams, Richard, Hurt, Chris
Publicado 2018

Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons

por Hague, Dominic, Townsend, Stephen, Masters, Lindsey, Rauchenberger, Mary, Van Looy, Nadine, Diaz-Montana, Carlos, Gannon, Melissa, James, Nicholas, Maughan, Tim, Parmar, Mahesh K. B., Brown, Louise, Sydes, Matthew R.
Publicado 2019