Widespread Site-Dependent Buffering of Human Regulatory Polymorphism

por Maurano, Matthew T., Wang, Hao, Kutyavin, Tanya, Stamatoyannopoulos, John A.
Publicado 2012

DNA methylation alone does not cause most cell-type selective transcription factor binding

por Maurano, Matthew T, Wang, Hao, Shafer, Anthony, John, Sam, Stamatoyannopoulos, John A
Publicado 2013

Big DNA as a tool to dissect an age-related macular degeneration-associated haplotype

por Laurent, Jon M, Fu, Xin, German, Sergei, Maurano, Matthew T, Zhang, Kang, Boeke, Jef D
Publicado 2019

Genomic context sensitivity of insulator function

por Ribeiro-dos-Santos, André M., Hogan, Megan S., Luther, Raven D., Brosh, Ran, Maurano, Matthew T.
Publicado 2022

Large-scale identification of sequence variants impacting human transcription factor occupancy in vivo

por Maurano, Matthew T., Haugen, Eric, Sandstrom, Richard, Vierstra, Jeff, Shafer, Anthony, Kaul, Rajinder, Stamatoyannopoulos, John A.
Publicado 2015

Analysis of Genetic Variation Indicates DNA Shape Involvement in Purifying Selection

por Wang, Xiaofei, Zhou, Tianyin, Wunderlich, Zeba, Maurano, Matthew T, DePace, Angela H, Nuzhdin, Sergey V, Rohs, Remo
Publicado 2018

Tissue context determines the penetrance of regulatory DNA variation

por Halow, Jessica M., Byron, Rachel, Hogan, Megan S., Ordoñez, Raquel, Groudine, Mark, Bender, M. A., Stamatoyannopoulos, John A., Maurano, Matthew T.
Publicado 2021

Personal and population genomics of human regulatory variation

por Vernot, Benjamin, Stergachis, Andrew B., Maurano, Matthew T., Vierstra, Jeff, Neph, Shane, Thurman, Robert E., Stamatoyannopoulos, John A., Akey, Joshua M.
Publicado 2012

A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications

por Zhang, Weimin, Brosh, Ran, McCulloch, Laura H., Zhu, Yinan, Ashe, Hannah, Ellis, Gwen, Camellato, Brendan R., Kim, Sang Yong, Maurano, Matthew T., Boeke, Jef D.
Publicado 2022

Genomic context sensitizes regulatory elements to genetic disruption

por Ordoñez, Raquel, Zhang, Weimin, Ellis, Gwen, Zhu, Yinan, Ashe, Hannah J., Ribeiro-dos-Santos, André M., Brosh, Ran, Huang, Emily, Hogan, Megan S., Boeke, Jef D., Maurano, Matthew T.
Publicado 2023

Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City

por Dellicour, Simon, Hong, Samuel L., Vrancken, Bram, Chaillon, Antoine, Gill, Mandev S., Maurano, Matthew T., Ramaswami, Sitharam, Zappile, Paul, Marier, Christian, Harkins, Gordon W., Baele, Guy, Duerr, Ralf, Heguy, Adriana
Publicado 2021

Widespread plasticity in CTCF occupancy linked to DNA methylation

por Wang, Hao, Maurano, Matthew T., Qu, Hongzhu, Varley, Katherine E., Gertz, Jason, Pauli, Florencia, Lee, Kristen, Canfield, Theresa, Weaver, Molly, Sandstrom, Richard, Thurman, Robert E., Kaul, Rajinder, Myers, Richard M., Stamatoyannopoulos, John A.
Publicado 2012

A versatile platform for locus-scale genome rewriting and verification

por Brosh, Ran, Laurent, Jon M., Ordoñez, Raquel, Huang, Emily, Hogan, Megan S., Hitchcock, Angela M., Mitchell, Leslie A., Pinglay, Sudarshan, Cadley, John A., Luther, Raven D., Truong, David M., Boeke, Jef D., Maurano, Matthew T.
Publicado 2021

De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca(2+) regulation

por Halvorsen, Matthew, Gould, Laura, Wang, Xiaohan, Grant, Gariel, Moya, Raquel, Rabin, Rachel, Ackerman, Michael J., Tester, David J., Lin, Peter T., Pappas, John G., Maurano, Matthew T., Goldstein, David B., Tsien, Richard W., Devinsky, Orrin
Publicado 2021

SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

por Elizondo, Victoria, Harkins, Gordon W., Mabvakure, Batsirai, Smidt, Sabine, Zappile, Paul, Marier, Christian, Maurano, Matthew, Perez, Victoria, Mazza, Natalia, Beloso, Carolina, Ifran, Silvana, Fernandez, Mariana, Santini, Andrea, Perez, Veronica, Estevez, Veronica, Nin, Matilde, Manrique, Gonzalo, Perez, Leticia, Ross, Fabiana, Boschi, Susana, Noel Zubillaga, Maria, Balleste, Raquel, Dellicour, Simon, Heguy, Adriana, Duerr, Ralf
Publicado 2020

SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

por Elizondo, Victoria, Harkins, Gordon W., Mabvakure, Batsirai, Smidt, Sabine, Zappile, Paul, Marier, Christian, Maurano, Matthew T., Perez, Victoria, Mazza, Natalia, Beloso, Carolina, Ifran, Silvana, Fernandez, Mariana, Santini, Andrea, Perez, Veronica, Estevez, Veronica, Nin, Matilde, Manrique, Gonzalo, Perez, Leticia, Ross, Fabiana, Boschi, Susana, Zubillaga, Maria Noel, Balleste, Raquel, Dellicour, Simon, Heguy, Adriana, Duerr, Ralf
Publicado 2021

Mouse genome rewriting and tailoring of three important disease loci

por Zhang, Weimin, Golynker, Ilona, Brosh, Ran, Fajardo, Alvaro, Zhu, Yinan, Wudzinska, Aleksandra M., Ordoñez, Raquel, Ribeiro-dos-Santos, André M., Carrau, Lucia, Damani-Yokota, Payal, Yeung, Stephen T., Khairallah, Camille, Vela Gartner, Antonio, Chalhoub, Noor, Huang, Emily, Ashe, Hannah J., Khanna, Kamal M., Maurano, Matthew T., Kim, Sang Yong, tenOever, Benjamin R., Boeke, Jef D.
Publicado 2023

An expansive human regulatory lexicon encoded in transcription factor footprints

por Neph, Shane, Vierstra, Jeff, Stergachis, Andrew B., Reynolds, Alex P., Haugen, Eric, Vernot, Benjamin, Thurman, Robert E., Sandstrom, Richard, Johnson, Audra K., Maurano, Matthew T., Humbert, Richard, Rynes, Eric, Wang, Hao, Vong, Shinny, Lee, Kristen, Bates, Daniel, Diegel, Morgan, Roach, Vaughn, Dunn, Douglas, Neri, Jun, Schafer, Anthony, Hansen, R. Scott, Kutyavin, Tanya, Giste, Erika, Weaver, Molly, Canfield, Theresa, Sabo, Peter, Zhang, Miaohua, Balasundaram, Gayathri, Byron, Rachel, MacCoss, Michael J., Akey, Joshua M., Bender, Michael, Groudine, Mark, Kaul, Rajinder, Stamatoyannopoulos, John A.
Publicado 2012

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

por Medina-Gomez, Carolina, Kemp, John P., Dimou, Niki L., Kreiner, Eskil, Chesi, Alessandra, Zemel, Babette S., Bønnelykke, Klaus, Boer, Cindy G., Ahluwalia, Tarunveer S., Bisgaard, Hans, Evangelou, Evangelos, Heppe, Denise H. M., Bonewald, Lynda F., Gorski, Jeffrey P., Ghanbari, Mohsen, Demissie, Serkalem, Duque, Gustavo, Maurano, Matthew T., Kiel, Douglas P., Hsu, Yi-Hsiang, C.J. van der Eerden, Bram, Ackert-Bicknell, Cheryl, Reppe, Sjur, Gautvik, Kaare M., Raastad, Truls, Karasik, David, van de Peppel, Jeroen, Jaddoe, Vincent W. V., Uitterlinden, André G., Tobias, Jonathan H., Grant, Struan F.A., Bagos, Pantelis G., Evans, David M., Rivadeneira, Fernando
Publicado 2017

The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes

por Berastegui, Nerea, Ainciburu, Marina, Romero, Juan P., Garcia-Olloqui, Paula, Alfonso-Pierola, Ana, Philippe, Céline, Vilas-Zornoza, Amaia, San Martin-Uriz, Patxi, Ruiz-Hernández, Raquel, Abarrategi, Ander, Ordoñez, Raquel, Alignani, Diego, Sarvide, Sarai, Castro-Labrador, Laura, Lamo-Espinosa, José M., San-Julian, Mikel, Jimenez, Tamara, López-Cadenas, Félix, Muntion, Sandra, Sanchez-Guijo, Fermin, Molero, Antonieta, Montoro, Maria Julia, Tazón, Bárbara, Serrano, Guillermo, Diaz-Mazkiaran, Aintzane, Hernaez, Mikel, Huerga, Sofía, Bewicke-Copley, Findlay, Rio-Machin, Ana, Maurano, Matthew T., Díez-Campelo, María, Valcarcel, David, Rouault-Pierre, Kevin, Lara-Astiaso, David, Ezponda, Teresa, Prosper, Felipe
Publicado 2022