The Cytoskeletal Protein RHAMM and ERK1/2 Activity Maintain the Pluripotency of Murine Embryonic Stem Cells

por Jiang, Jihong, Mohan, Pooja, Maxwell, Christopher A.
Publicado 2013

Diet as a Potential Moderator for Genome Stability and Immune Response in Pediatric Leukemia

por Wang, Shanshan, Maxwell, Christopher A., Akella, Neha M.
Publicado 2021

Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan Receptor

por He, Zhengcheng, Mei, Lin, Connell, Marisa, Maxwell, Christopher A.
Publicado 2020

The nonmotor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation

por Chen, Helen, Connell, Marisa, Mei, Lin, Reid, Gregor S. D., Maxwell, Christopher A.
Publicado 2018

Multifunctional Proteins Bridge Mitosis with Motility and Cancer with Inflammation and Arthritis

por Jiang, Jihong, Casalegno-Garduno, Rosaely, Chen, Helen, Schmitt, Anita, Schmitt, Michael, Maxwell, Christopher A.
Publicado 2010

Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment

por Maxwell, Christopher A, Moreno, Víctor, Solé, Xavier, Gómez, Laia, Hernández, Pilar, Urruticoechea, Ander, Pujana, Miguel Angel
Publicado 2008

Centrosome Amplification Is a Potential Molecular Target in Paediatric Acute Lymphoblastic Leukemia

por Guo, Meiyun, Rever, Jenna, Nguyen, Phuong N. U., Akella, Neha M., Reid, Gregor S. D., Maxwell, Christopher A.
Publicado 2022

CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment

por Lee-Sayer, Sally S. M., Dougan, Meghan N., Cooper, Jesse, Sanderson, Leslie, Dosanjh, Manisha, Maxwell, Christopher A., Johnson, Pauline
Publicado 2018

Adaptation of the Th-MYCN Mouse Model of Neuroblastoma for Evaluation of Disseminated Disease

por Rahavi, Seyed M., Aletaha, Maryam, Farrokhi, Ali, Lorentzian, Amanda, Lange, Philipp F., Maxwell, Christopher A., Lim, Chinten James, Reid, Gregor S. D.
Publicado 2023

A cross‐standardized flow cytometry platform to assess phenotypic stability in precursor B‐cell acute lymphoblastic leukemia (B‐ALL) xenografts

por Rolf, Nina, Liu, Lorraine Y. T., Tsang, Angela, Lange, Philipp F., Lim, Chinten James, Maxwell, Christopher A., Vercauteren, Suzanne M., Reid, Gregor S. D.
Publicado 2021

Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia

por Lorentzian, Amanda C., Rever, Jenna, Ergin, Enes K., Guo, Meiyun, Akella, Neha M., Rolf, Nina, James Lim, C., Reid, Gregor S. D., Maxwell, Christopher A., Lange, Philipp F.
Publicado 2023

BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

por He, Zhengcheng, Kannan, Nagarajan, Nemirovsky, Oksana, Chen, Helen, Connell, Marisa, Taylor, Brian, Jiang, Jihong, Pilarski, Linda M., Fleisch, Markus C., Niederacher, Dieter, Pujana, Miguel Angel, Eaves, Connie J., Maxwell, Christopher A.
Publicado 2017

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

por He, Zhengcheng, Ghorayeb, Ryan, Tan, Susanna, Chen, Ke, Lorentzian, Amanda C., Bottyan, Jack, Aalam, Syed Mohammed Musheer, Pujana, Miguel Angel, Lange, Philipp F., Kannan, Nagarajan, Eaves, Connie J., Maxwell, Christopher A.
Publicado 2022

Biological Convergence of Cancer Signatures

por Solé, Xavier, Bonifaci, Núria, López-Bigas, Núria, Berenguer, Antoni, Hernández, Pilar, Reina, Oscar, Maxwell, Christopher A., Aguilar, Helena, Urruticoechea, Ander, de Sanjosé, Silvia, Comellas, Francesc, Capellá, Gabriel, Moreno, Víctor, Pujana, Miguel Angel
Publicado 2009

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

por Uzozie, Anuli C., Ergin, Enes K., Rolf, Nina, Tsui, Janice, Lorentzian, Amanda, Weng, Samuel S. H., Nierves, Lorenz, Smith, Theodore G., Lim, C. James, Maxwell, Christopher A., Reid, Gregor S. D., Lange, Philipp F.
Publicado 2021

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

por Fulcher, Luke J, He, Zhengcheng, Mei, Lin, Macartney, Thomas J, Wood, Nicola T, Prescott, Alan R, Whigham, Arlene J, Varghese, Joby, Gourlay, Robert, Ball, Graeme, Clarke, Rosemary, Campbell, David G, Maxwell, Christopher A, Sapkota, Gopal P
Publicado 2019

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition

por Mohan, Pooja, Castellsague, Joan, Jiang, Jihong, Allen, Kristi, Chen, Helen, Nemirovsky, Oksana, Spyra, Melanie, Hu, Kaiji, Kluwe, Lan, Pujana, Miguel Angel, Villanueva, Alberto, Mautner, Victor F., Keats, Jonathan J., Dunn, Sandra E., Lazaro, Conxi, Maxwell, Christopher A.
Publicado 2013

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

por Lorentzian, Amanda, Biegel, Jaclyn A, Ostrow, D Gigi, Rolf, Nina, Liu, Chi-Chao, Rassekh, S Rod, Deyell, Rebecca J, Triche, Timothy, Schultz, Kirk R, Rozmus, Jacob, Reid, Gregor S D, Lim, C James, Lange, Philipp F, Maxwell, Christopher A
Publicado 2019

Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility

por Solé, Xavier, Hernández, Pilar, de Heredia, Miguel López, Armengol, Lluís, Rodríguez-Santiago, Benjamín, Gómez, Laia, Maxwell, Christopher A, Aguiló, Fernando, Condom, Enric, Abril, Jesús, Pérez-Jurado, Luis, Estivill, Xavier, Nunes, Virginia, Capellá, Gabriel, Gruber, Stephen B, Moreno, Víctor, Pujana, Miguel Angel
Publicado 2008

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

por Connell, Marisa, Chen, Helen, Jiang, Jihong, Kuan, Chia-Wei, Fotovati, Abbas, Chu, Tony LH, He, Zhengcheng, Lengyell, Tess C, Li, Huaibiao, Kroll, Torsten, Li, Amanda M, Goldowitz, Daniel, Frappart, Lucien, Ploubidou, Aspasia, Patel, Millan S, Pilarski, Linda M, Simpson, Elizabeth M, Lange, Philipp F, Allan, Douglas W, Maxwell, Christopher A
Publicado 2017