Reversible Linkage of Two Distinct Small Molecule Inhibitors of Myc Generates a Dimeric Inhibitor with Improved Potency That Is Active in Myc Over-Expressing Cancer Cell Lines

por Wanner, Jutta, Romashko, Darlene, Werner, Douglas S., May, Earl W., Peng, Yue, Schulz, Ryan, Foreman, Kenneth W., Russo, Suzanne, Arnold, Lee D., Pingle, Maneesh, Bergstrom, Donald E., Barany, Francis, Thomson, Stuart
Publicado 2015

Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

por Heppner, David, Wittlinger, Florian, Ogboo, Blessing, Shevchenko, Ekaterina, Damghani, Tahereh, Pham, Calvin, Schaeffner, Ilse, Oligny, Brandon, Chitnis, Surbhi, Beyett, Tyler, Rasch, Alexander, Buckley, Brian, Urul, Daniel, Shaurova, Tatiana, May, Earl, Schaefer, Erik, Eck, Michael, Hershberger, Pamela, Poso, Antti, Laufer, Stefan
Publicado 2023