Characterisation of endogenous A(2A) and A(2B) receptor-mediated cyclic AMP responses in HEK 293 cells using the GloSensor™ biosensor: Evidence for an allosteric mechanism of actio...

por Goulding, Joelle, May, Lauren T., Hill, Stephen J.
Publicado 2018

Targeting Adenosine Receptors for the Treatment of Cardiac Fibrosis

por Vecchio, Elizabeth A., White, Paul J., May, Lauren T.
Publicado 2017

Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A(1) Receptor

por Miao, Yinglong, Bhattarai, Apurba, Nguyen, Anh T. N., Christopoulos, Arthur, May, Lauren T.
Publicado 2018

Sex Differences in Lung Cancer

por May, Lauren, Shows, Kathryn, Nana-Sinkam, Patrick, Li, Howard, Landry, Joseph W.
Publicado 2023

Intussusception after Laparoscopic Gastric Bypass Surgery: An Underrecognized Complication

por Singla, Smit, Guenthart, Brandon A., May, Lauren, Gaughan, John, Meilahn, John E.
Publicado 2012

Negative cooperativity across β(1)-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation

por Gherbi, Karolina, May, Lauren T., Baker, Jillian G., Briddon, Stephen J., Hill, Stephen J.
Publicado 2015

Allosteric interactions across native adenosine-A(3) receptor homodimers: quantification using single-cell ligand-binding kinetics

por May, Lauren T., Bridge, Lloyd J., Stoddart, Leigh A., Briddon, Stephen J., Hill, Stephen J.
Publicado 2011

Mode of action evaluation for reduced reproduction in Daphnia pulex exposed to the insensitive munition, 1-methyl-3-nitro-1-nitroguanidine (MeNQ)

por Gust, Kurt A., Lotufo, Guilherme R., Barker, Natalie D., Ji, Qing, May, Lauren K.
Publicado 2021

Adenosine receptor signalling in Alzheimer’s disease

por Trinh, Phuc N. H., Baltos, Jo-Anne, Hellyer, Shane D., May, Lauren T., Gregory, Karen J.
Publicado 2022

Publisher Correction to: Adenosine receptor signalling in Alzheimer’s disease

por Trinh, Phuc N. H., Baltos, Jo-Anne, Hellyer, Shane D., May, Lauren T., Gregory, Karen J.
Publicado 2022

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A(1) receptor ligands

por Baker, Jillian G, Middleton, Richard, Adams, Luke, May, Lauren T, Briddon, Stephen J, Kellam, Barrie, Hill, Stephen J
Publicado 2010

Small molecule allosteric modulation of the adenosine A(1) receptor

por Nguyen, Anh T. N., Tran, Quan L., Baltos, Jo-Anne, McNeill, Samantha M., Nguyen, Diep T. N., May, Lauren T.
Publicado 2023

Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

por Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.
Publicado 2018

Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus

por Roberts, Maxine J., May, Lauren T., Keen, Alastair C., Liu, Bonan, Lam, Terrance, Charlton, Steven J., Rosethorne, Elizabeth M., Halls, Michelle L.
Publicado 2021

Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35

por Qin, Cheng Xue, Norling, Lucy V., Vecchio, Elizabeth A., Brennan, Eoin P., May, Lauren T., Wootten, Denise, Godson, Catherine, Perretti, Mauro, Ritchie, Rebecca H.
Publicado 2022

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

por May, Lauren T., Bartolo, Belinda A., Harrison, David G., Guzik, Tomasz, Drummond, Grant R., Figtree, Gemma A., Ritchie, Rebecca H., Rye, Kerry-Anne, de Haan, Judy B.
Publicado 2022

Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

por Rueda, Patricia, Merlin, Jon, Chimenti, Stefano, Feletou, Michel, Paysant, Jerome, White, Paul J., Christopoulos, Arthur, Sexton, Patrick M., Summers, Roger J., Charman, William N., May, Lauren T., Langmead, Christopher J.
Publicado 2021

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

por Qin, Cheng Xue, May, Lauren T., Li, Renming, Cao, Nga, Rosli, Sarah, Deo, Minh, Alexander, Amy E., Horlock, Duncan, Bourke, Jane E., Yang, Yuan H., Stewart, Alastair G., Kaye, David M., Du, Xiao-Jun, Sexton, Patrick M., Christopoulos, Arthur, Gao, Xiao-Ming, Ritchie, Rebecca H.
Publicado 2017

Structure-based discovery of selective positive allosteric modulators of antagonists for the M(2) muscarinic acetylcholine receptor

por Korczynska, Magdalena, Clark, Mary J., Valant, Celine, Xu, Jun, Moo, Ee Von, Albold, Sabine, Weiss, Dahlia R., Torosyan, Hayarpi, Huang, Weijiao, Kruse, Andrew C., Lyda, Brent R., May, Lauren T., Baltos, Jo-Anne, Sexton, Patrick M., Kobilka, Brian K., Christopoulos, Arthur, Shoichet, Brian K., Sunahara, Roger K.
Publicado 2018