Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

por Sureban, Sripathi M, May, Randal, Mondalek, Fadee G, Qu, Dongfeng, Ponnurangam, Sivapriya, Pantazis, Panayotis, Anant, Shrikant, Ramanujam, Rama P, Houchen, Courtney W
Publicado 2011

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis

por Qu, Dongfeng, Weygant, Nathaniel, May, Randal, Chandrakesan, Parthasarathy, Madhoun, Mohammad, Ali, Naushad, Sureban, Sripathi M., An, Guangyu, Schlosser, Michael J., Houchen, Courtney W.
Publicado 2015

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1

por Weygant, Nathaniel, Qu, Dongfeng, Berry, William L, May, Randal, Chandrakesan, Parthasarathy, Owen, Daniel B, Sureban, Sripathi M, Ali, Naushad, Janknecht, Ralf, Houchen, Courtney W
Publicado 2014

Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition

por Chandrakesan, Parthasarathy, Weygant, Nathaniel, May, Randal, Qu, Dongfeng, Chinthalapally, Harisha R., Sureban, Sripathi M., Ali, Naushad, Lightfoot, Stan A., Umar, Shahid, Houchen, Courtney W.
Publicado 2014

Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury

por Chandrakesan, Parthasarathy, May, Randal, Weygant, Nathaniel, Qu, Dongfeng, Berry, William L., Sureban, Sripathi M., Ali, Naushad, Rao, Chinthalapally, Huycke, Mark, Bronze, Michael S., Houchen, Courtney W.
Publicado 2016

DCLK1 Monoclonal Antibody-Based CAR-T Cells as a Novel Treatment Strategy against Human Colorectal Cancers

por Sureban, Sripathi M., Berahovich, Robert, Zhou, Hua, Xu, Shirley, Wu, Lijun, Ding, Kai, May, Randal, Qu, Dongfeng, Bannerman-Menson, Edwin, Golubovskaya, Vita, Houchen, Courtney W.
Publicado 2019

Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury

por Sureban, Sripathi M., May, Randal, Qu, Dongfeng, Chandrakesan, Parthasarathy, Weygant, Nathaniel, Ali, Naushad, Lightfoot, Stan A., Ding, Kai, Umar, Shahid, Schlosser, Michael J., Houchen, Courtney W.
Publicado 2015

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism

por Sureban, Sripathi M., Madhoun, Mohammad F., May, Randal, Qu, Dongfeng, Ali, Naushad, Fazili, Javid, Weygant, Nathaniel, Chandrakesan, Parthasarathy, Ding, Kai, Lightfoot, Stanley A., Houchen, Courtney W.
Publicado 2015

DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer

por Sureban, Sripathi M., May, Randal, Qu, Dongfeng, Weygant, Nathaniel, Chandrakesan, Parthasarathy, Ali, Naushad, Lightfoot, Stan A., Pantazis, Panayotis, Rao, Chinthalapally V., Postier, Russell G., Houchen, Courtney W.
Publicado 2013

Dclk1(+) small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal

por Chandrakesan, Parthasarathy, May, Randal, Qu, Dongfeng, Weygant, Nathaniel, Taylor, Vivian E., Li, James D., Ali, Naushad, Sureban, Sripathi M., Qante, Michael, Wang, Timothy C., Bronze, Michael S., Houchen, Courtney W.
Publicado 2015

Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism

por Ali, Naushad, Nguyen, Charles B., Chandrakesan, Parthasarathy, Wolf, Roman F., Qu, Dongfeng, May, Randal, Goretsky, Tatiana, Fazili, Javid, Barrett, Terrence A., Li, Min, Huycke, Mark M., Bronze, Michael S., Houchen, Courtney W.
Publicado 2020

Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells

por Chandrakesan, Parthasarathy, Yao, Jiannan, Qu, Dongfeng, May, Randal, Weygant, Nathaniel, Ge, Yang, Ali, Naushad, Sureban, Sripathi M., Gude, Modhi, Vega, Kenneth, Bannerman-Menson, Eddie, Xia, Lijun, Bronze, Michael, An, Guangyu, Houchen, Courtney W.
Publicado 2017

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer

por Qu, Dongfeng, Weygant, Nathaniel, Yao, Jiannan, Chandrakesan, Parthasarathy, Berry, William L., May, Randal, Pitts, Kamille, Husain, Sanam, Lightfoot, Stan, Li, Min, Wang, Timothy C., An, Guangyu, Clendenin, Cynthia, Stanger, Ben Z., Houchen, Courtney W.
Publicado 2019

Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism

por Ali, Naushad, Allam, Heba, Bader, Ted, May, Randal, Basalingappa, Kanthesh M., Berry, William L., Chandrakesan, Parthasarathy, Qu, Dongfeng, Weygant, Nathaniel, Bronze, Michael S., Umar, Shahid, Janknecht, Ralf, Sureban, Sripathi M., Huycke, Mark, Houchen, Courtney W.
Publicado 2013

Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism

por Ali, Naushad, Allam, Heba, Bader, Ted, May, Randal, Basalingappa, Kanthesh M., Berry, William L., Chandrakesan, Parthasarathy, Qu, Dongfeng, Weygant, Nathaniel, Bronze, Michael S., Umar, Shahid, Janknecht, Ralf, Sureban, Sripathi M., Huycke, Mark, Houchen, Courtney W.
Publicado 2013

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases

por Ali, Naushad, Chandrakesan, Parthasarathy, Nguyen, Charles B., Husain, Sanam, Gillaspy, Allison F., Huycke, Mark, Berry, William L., May, Randal, Qu, Dongfeng, Weygant, Nathaniel, Sureban, Sripathi M., Bronze, Michael S., Dhanasekaran, Danny N., Houchen, Courtney W.
Publicado 2015

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

por Weygant, Nathaniel, Qu, Dongfeng, May, Randal, Tierney, Ryan M., Berry, William L., Zhao, Lichao, Agarwal, Shweta, Chandrakesan, Parthasarathy, Chinthalapally, Harisha R., Murphy, Nicholas T., Li, James D., Sureban, Sripathi M., Schlosser, Michael J., Tomasek, James J., Houchen, Courtney W.
Publicado 2014

Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression

por Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Brewer, Misty, Ritchie, Rebekah L., Lightfoot, Stan, Kumar, Gaurav, Sadeghi, Michael, Patlolla, Jagan Mohan R., Yamada, Hiroshi Y., Cruz-Monserrate, Zobeida, May, Randal, Houchen, Courtney W., Steele, Vernon E., Rao, Chinthalapally V.
Publicado 2015

Doublecortin-Like Kinase 1 Is Elevated Serologically in Pancreatic Ductal Adenocarcinoma and Widely Expressed on Circulating Tumor Cells

por Qu, Dongfeng, Johnson, Jeremy, Chandrakesan, Parthasarathy, Weygant, Nathaniel, May, Randal, Aiello, Nicole, Rhim, Andrew, Zhao, Lichao, Zheng, Wei, Lightfoot, Stanley, Pant, Shubham, Irvan, Jeremy, Postier, Russell, Hocker, James, Hanas, Jay S., Ali, Naushad, Sureban, Sripathi M., An, Guangyu, Schlosser, Michael J., Stanger, Ben, Houchen, Courtney W.
Publicado 2015