Wrong person, place and time: viral load and contact network structure predict SARS-CoV-2 transmission and super-spreading events

por Goyal, Ashish, Reeves, Daniel B., Cardozo-Ojeda, E. Fabian, Schiffer, Joshua T., Mayer, Bryan T.
Publicado 2020

Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events

por Goyal, Ashish, Reeves, Daniel B, Cardozo-Ojeda, E Fabian, Schiffer, Joshua T, Mayer, Bryan T
Publicado 2021

Estimating the Risk of Human Herpesvirus 6 and Cytomegalovirus Transmission to Ugandan Infants from Viral Shedding in Saliva by Household Contacts

por Mayer, Bryan T., Krantz, Elizabeth M., Wald, Anna, Corey, Lawrence, Casper, Corey, Gantt, Soren, Schiffer, Joshua T.
Publicado 2020

DataPackageR: Reproducible data preprocessing, standardization and sharing using R/Bioconductor for collaborative data analysis

por Finak, Greg, Mayer, Bryan, Fulp, William, Obrecht, Paul, Sato, Alicia, Chung, Eva, Holman, Drienna, Gottardo, Raphael
Publicado 2018

Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir

por Roychoudhury, Pavitra, De Silva Feelixge, Harshana, Reeves, Daniel, Mayer, Bryan T., Stone, Daniel, Schiffer, Joshua T., Jerome, Keith R.
Publicado 2018

Slight reduction in SARS-CoV-2 exposure viral load due to masking results in a significant reduction in transmission with widespread implementation

por Goyal, Ashish, Reeves, Daniel B., Thakkar, Niket, Famulare, Mike, Cardozo-Ojeda, E. Fabián, Mayer, Bryan T., Schiffer, Joshua T.
Publicado 2021

Estimation of the in vivo neutralization potency of eCD4Ig and conditions for AAV-mediated production for SHIV long-term remission

por Goyal, Ashish, Gardner, Matthew, Mayer, Bryan T., Jerome, Keith R., Farzan, Michael, Schiffer, Joshua T., Cardozo-Ojeda, E. Fabian
Publicado 2022

Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention

por Mayer, Bryan T., deCamp, Allan C., Huang, Yunda, Schiffer, Joshua T., Gottardo, Raphael, Gilbert, Peter B., Reeves, Daniel B.
Publicado 2022

Virus and host-specific differences in oral human herpesvirus shedding kinetics among Ugandan women and children

por Matrajt, Laura, Gantt, Soren, Mayer, Bryan T., Krantz, Elizabeth M., Orem, Jackson, Wald, Anna, Corey, Lawrence, Schiffer, Joshua T., Casper, Corey
Publicado 2017

Thresholds for post-rebound SHIV control after CCR5 gene-edited autologous hematopoietic cell transplantation

por Cardozo-Ojeda, E Fabian, Duke, Elizabeth R, Peterson, Christopher W, Reeves, Daniel B, Mayer, Bryan T, Kiem, Hans-Peter, Schiffer, Joshua T
Publicado 2021

Timing HIV infection with a simple and accurate population viral dynamics model

por Reeves, Daniel B., Rolland, Morgane, Dearlove, Bethany L., Li, Yifan, Robb, Merlin L., Schiffer, Joshua T., Gilbert, Peter, Cardozo-Ojeda, E. Fabian, Mayer, Bryan T.
Publicado 2021

Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

por Raghunandan, Rama, Mayer, Bryan T., Flores-Garcia, Yevel, Gerber, Monica W., Gottardo, Raphael, Jhun, Hugo, Herrera, Sonia M., Perez-Ramos, Daniel W., Locke, Emily, King, C. Richter, Zavala, Fidel
Publicado 2020

Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity

por Kerwin, Bruce A., Bennett, Chelsey, Brodsky, Yan, Clark, Rutilio, Floyd, J. Alaina, Gillespie, Alison, Mayer, Bryan T., McClure, Megan, Siska, Christine, Seaman, Michael S., Seaton, Kelly E., Shaver, Jeremy, Tomaras, Georgia D., Yates, Nicole L., Ketchem, Randal R.
Publicado 2020

Mathematical modeling to reveal breakthrough mechanisms in the HIV Antibody Mediated Prevention (AMP) trials

por Reeves, Daniel B., Huang, Yunda, Duke, Elizabeth R., Mayer, Bryan T., Cardozo-Ojeda, E. Fabian, Boshier, Florencia A., Swan, David A., Rolland, Morgane, Robb, Merlin L., Mascola, John R., Cohen, Myron S., Corey, Lawrence, Gilbert, Peter B., Schiffer, Joshua T.
Publicado 2020

Optimal priming of poxvirus vector (NYVAC)-based HIV vaccine regimens for T cell responses requires three DNA injections. Results of the randomized multicentre EV03/ANRS VAC20 Phas...

por Lévy, Yves, Lacabaratz, Christine, Ellefsen-Lavoie, Kim, Stöhr, Wolfgang, Lelièvre, Jean-Daniel, Bart, Pierre-Alexandre, Launay, Odile, Weber, Jonathan, Salzberger, Bernd, Wiedemann, Aurélie, Surenaud, Mathieu, Koelle, David M., Wolf, Hans, Wagner, Ralf, Rieux, Véronique, Montefiori, David C., Yates, Nicole L., Tomaras, Georgia D., Gottardo, Raphael, Mayer, Bryan, Ding, Song, Thiébaut, Rodolphe, McCormack, Sheena, Chêne, Geneviève, Pantaleo, Giuseppe
Publicado 2020

Safety and immunogenicity of an HIV-1 gp120-CD4 chimeric subunit vaccine in a phase 1a randomized controlled trial

por Chua, Joel V., Davis, Charles, Husson, Jennifer S., Nelson, Amy, Prado, Ilia, Flinko, Robin, Lam, Ka Wing J., Mutumbi, Lydiah, Mayer, Bryan T., Dong, Dan, Fulp, William, Mahoney, Celia, Gerber, Monica, Gottardo, Raphael, Gilliam, Bruce L., Greene, Kelli, Gao, Hongmei, Yates, Nicole, Ferrari, Guido, Tomaras, Georgia, Montefiori, David, Schwartz, Jennifer A., Fouts, Timothy, DeVico, Anthony L., Lewis, George K., Gallo, Robert C., Sajadi, Mohammad M.
Publicado 2021

Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study

por Cohen, Yehuda Z., Butler, Allison L., Millard, Katrina, Witmer-Pack, Maggi, Levin, Rebeka, Unson-O’Brien, Cecilia, Patel, Roshni, Shimeliovich, Irina, Lorenzi, Julio C. C., Horowitz, Jill, Walsh, Stephen R., Lin, Shu, Weiner, Joshua A., Tse, Anna, Sato, Alicia, Bennett, Chelsey, Mayer, Bryan, Seaton, Kelly E., Yates, Nicole L., Baden, Lindsey R., deCamp, Allan C., Ackerman, Margaret E., Seaman, Michael S., Tomaras, Georgia D., Nussenzweig, Michel C., Caskey, Marina
Publicado 2019

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

por Julg, Boris, Stephenson, Kathryn E., Wagh, Kshitij, Tan, Sabrina C., Zash, Rebecca, Walsh, Stephen, Ansel, Jessica, Kanjilal, Diane, Nkolola, Joseph, Walker-Sperling, Victoria E. K., Ophel, Jasper, Yanosick, Katherine, Borducchi, Erica N., Maxfield, Lori, Abbink, Peter, Peter, Lauren, Yates, Nicole L., Wesley, Martina S., Hassell, Tom, Gelderblom, Huub C., deCamp, Allen, Mayer, Bryan T., Sato, Alicia, Gerber, Monica W., Giorgi, Elena E., Gama, Lucio, Koup, Richard A., Mascola, John R., Monczor, Ana, Lupo, Sofia, Rolle, Charlotte-Paige, Arduino, Roberto, DeJesus, Edwin, Tomaras, Georgia D., Seaman, Michael S., Korber, Bette, Barouch, Dan H.
Publicado 2022

Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial

por Stephenson, Kathryn E., Julg, Boris, Tan, C. Sabrina, Zash, Rebecca, Walsh, Stephen R., Rolle, Charlotte-Paige, Monczor, Ana N., Lupo, Sofia, Gelderblom, Huub C., Ansel, Jessica L., Kanjilal, Diane G., Maxfield, Lori F., Nkolola, Joseph, Borducchi, Erica N., Abbink, Peter, Liu, Jinyan, Peter, Lauren, Chandrashekar, Abishek, Nityanandam, Ramya, Lin, Zijin, Setaro, Alessandra, Sapiente, Joseph, Chen, Zhilin, Sunner, Lisa, Cassidy, Tyler, Bennett, Chelsey, Sato, Alicia, Mayer, Bryan, Perelson, Alan S., deCamp, Allan, Priddy, Frances H., Wagh, Kshitij, Giorgi, Elena E., Yates, Nicole L., Arduino, Roberto C., DeJesus, Edwin, Tomaras, Georgia D., Seaman, Michael S., Korber, Bette, Barouch, Dan H.
Publicado 2021

Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition

por Gilbert, Peter B., Huang, Yunda, deCamp, Allan C., Karuna, Shelly, Zhang, Yuanyuan, Magaret, Craig A., Giorgi, Elena E., Korber, Bette, Edlefsen, Paul T., Rossenkhan, Raabya, Juraska, Michal, Rudnicki, Erika, Kochar, Nidhi, Huang, Ying, Carpp, Lindsay N., Barouch, Dan H., Mkhize, Nonhlanhla N., Hermanus, Tandile, Kgagudi, Prudence, Bekker, Valerie, Kaldine, Haajira, Mapengo, Rutendo E., Eaton, Amanda, Domin, Elize, West, Carley, Feng, Wenhong, Tang, Haili, Seaton, Kelly E., Heptinstall, Jack, Brackett, Caroline, Chiong, Kelvin, Tomaras, Georgia D., Andrew, Philip, Mayer, Bryan T., Reeves, Daniel B., Sobieszczyk, Magdalena E., Garrett, Nigel, Sanchez, Jorge, Gay, Cynthia, Makhema, Joseph, Williamson, Carolyn, Mullins, James I., Hural, John, Cohen, Myron S., Corey, Lawrence, Montefiori, David C., Morris, Lynn
Publicado 2022