A review of protocols for brain organoids and applications for disease modeling

por Mayhew, Christopher N., Singhania, Richa
Publicado 2022

Digitalized Human Organoid for Wireless Phenotyping

por Kimura, Masaki, Azuma, Momoko, Zhang, Ran-Ran, Thompson, Wendy, Mayhew, Christopher N., Takebe, Takanori
Publicado 2018

Properties of Neurons Derived from Induced Pluripotent Stem Cells of Gaucher Disease Type 2 Patient Fibroblasts: Potential Role in Neuropathology

por Sun, Ying, Florer, Jane, Mayhew, Christopher N., Jia, Zhanfeng, Zhao, Zhiying, Xu, Kui, Ran, Huimin, Liou, Benjamin, Zhang, Wujuan, Setchell, Kenneth D. R., Gu, Jianguo, Grabowski, Gregory A.
Publicado 2015

Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage

por Chlon, Timothy M., Ruiz-Torres, Sonya, Maag, Logan, Mayhew, Christopher N., Wikenheiser-Brokamp, Kathryn A., Davies, Stella M., Mehta, Parinda, Myers, Kasiani C., Wells, James M., Wells, Susanne I.
Publicado 2016

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids

por Xia, Sunny, Bozóky, Zoltán, Di Paola, Michelle, Laselva, Onofrio, Ahmadi, Saumel, Jiang, Jia Xin, Pitstick, Amy L., Jiang, Chong, Rotin, Daniela, Mayhew, Christopher N., Jones, Nicola L., Bear, Christine E.
Publicado 2021

Modeling human development and disease in pluripotent stem cell-derived gastric organoids

por McCracken, Kyle W., Catá, Emily M., Crawford, Calyn M., Sinagoga, Katie L., Schumacher, Michael, Rockich, Briana E., Tsai, Yu-Hwai, Mayhew, Christopher N., Spence, Jason R., Zavros, Yana, Wells, James M.
Publicado 2014

Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation

por Pitstick, Amy L., Poling, Holly M., Sundaram, Nambirajan, Lewis, Phillip L., Kechele, Daniel O., Sanchez, J. Guillermo, Scott, Melissa A., Broda, Taylor R., Helmrath, Michael A., Wells, James M., Mayhew, Christopher N.
Publicado 2022

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

por Spence, Jason R., Mayhew, Christopher N., Rankin, Scott A., Kuhar, Matthew, Vallance, Jefferson E., Tolle, Kathryn, Hoskins, Elizabeth E., Kalinichenko, Vladimir V., Wells, Susanne I., Zorn, Aaron M., Shroyer, Noah F., Wells, James M.
Publicado 2010

Activated STAT5 Confers Resistance to Intestinal Injury by Increasing Intestinal Stem Cell Proliferation and Regeneration

por Gilbert, Shila, Nivarthi, Harini, Mayhew, Christopher N., Lo, Yuan-Hung, Noah, Taeko K., Vallance, Jefferson, Rülicke, Thomas, Müller, Mathias, Jegga, Anil G., Tang, Wenjuan, Zhang, Dongsheng, Helmrath, Michael, Shroyer, Noah, Moriggl, Richard, Han, Xiaonan
Publicado 2015

In vitro generation of human pluripotent stem cell derived lung organoids

por Dye, Briana R, Hill, David R, Ferguson, Michael AH, Tsai, Yu-Hwai, Nagy, Melinda S, Dyal, Rachel, Wells, James M, Mayhew, Christopher N, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R
Publicado 2015

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

por Li, Chao Zheng, Ogawa, Hiromi, Ng, Soon Seng, Chen, Xindi, Kishimoto, Eriko, Sakabe, Kokoro, Fukami, Aiko, Hu, Yueh-Chiang, Mayhew, Christopher N., Hellmann, Jennifer, Miethke, Alexander, Tasnova, Nahrin L., Blackford, Samuel J.I., Tang, Zu Ming, Syanda, Adam M., Ma, Liang, Xiao, Fang, Sambrotta, Melissa, Tavabie, Oliver, Soares, Filipa, Baker, Oliver, Danovi, Davide, Hayashi, Hisamitsu, Thompson, Richard J., Rashid, S. Tamir, Asai, Akihiro
Publicado 2022

Noncoding Deletions Expose a Novel Gene Critical for Intestinal Function

por Oz-Levi, Danit, Olender, Tsviya, Bar-Joseph, Ifat, Zhu, Yiwen, Marek-Yagel, Dina, Barozzi, Iros, Osterwalder, Marco, Alkelai, Anna, Ruzzo, Elizabeth K., Han, Yujun, Vos, Erica S. M., Reznik-Wolf, Haike, Hartman, Corina, Shamir, Raanan, Weiss, Batia, Shapiro, Rivka, Pode-Shakked, Ben, Tatarskyy, Pavlo, Milgrom, Roni, Schvimer, Michael, Barshack, Iris, Imai, Denise M., Coleman-Derr, Devin, Dickel, Diane E., Nord, Alex S., Afzal, Veena, van Bueren, Kelly Lammerts, Barnes, Ralston M., Black, Brian L., Mayhew, Christopher N., Kuhar, Matthew F., Pitstick, Amy, Tekman, Mehmet, Stanescu, Horia C., Wells, James M., Kleta, Robert, de Laat, Wouter, Goldstein, David B., Pras, Elon, Visel, Axel, Lancet, Doron, Anikster, Yair, Pennacchio, Len A.
Publicado 2019