The Role of Micronutrients in Graft-VS.-Host Disease: Immunomodulatory Effects of Vitamins A and D

por Chen, Xiao, Mayne, Christopher G.
Publicado 2018

Atomistic Models of General Anesthetics for Use in in Silico Biological Studies

por Arcario, Mark J., Mayne, Christopher G., Tajkhorshid, Emad
Publicado 2014

A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus ion channel

por Arcario, Mark J., Mayne, Christopher G., Tajkhorshid, Emad
Publicado 2017

All-Atom Molecular Dynamics of Virus Capsids as Drug Targets

por Perilla, Juan R., Hadden, Jodi A., Goh, Boon Chong, Mayne, Christopher G., Schulten, Klaus
Publicado 2016

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer

por Mayne, Christopher G., Toy, Weiyi, Carlson, Kathryn E., Bhatt, Trusha, Fanning, Sean W., Greene, Geoffrey L., Katzenellenbogen, Benita S., Chandarlapaty, Sarat, Katzenellenbogen, John A., Tajkhorshid, Emad
Publicado 2021

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

por Fanning, Sean W, Mayne, Christopher G, Dharmarajan, Venkatasubramanian, Carlson, Kathryn E, Martin, Teresa A, Novick, Scott J, Toy, Weiyi, Green, Bradley, Panchamukhi, Srinivas, Katzenellenbogen, Benita S, Tajkhorshid, Emad, Griffin, Patrick R, Shen, Yang, Chandarlapaty, Sarat, Katzenellenbogen, John A, Greene, Geoffrey L
Publicado 2016

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

por Fanning, Sean W, Jeselsohn, Rinath, Dharmarajan, Venkatasubramanian, Mayne, Christopher G, Karimi, Mostafa, Buchwalter, Gilles, Houtman, René, Toy, Weiyi, Fowler, Colin E, Han, Ross, Lainé, Muriel, Carlson, Kathryn E, Martin, Teresa A, Nowak, Jason, Nwachukwu, Jerome C, Hosfield, David J, Chandarlapaty, Sarat, Tajkhorshid, Emad, Nettles, Kendall W, Griffin, Patrick R, Shen, Yang, Katzenellenbogen, John A, Brown, Myles, Greene, Geoffrey L
Publicado 2018